Results 101 to 110 of about 1,940,445 (217)

Overexpression of Global Regulator PbrlaeA Leads to the Discovery of New Polyketide in Fungus Penicillium Brocae HDN-12-143

open access: yesFrontiers in Chemistry, 2020
Overexpression of the PbrlaeA gene of the fungus Penicillium brocae HDN-12-143 resulted in the isolation of four compounds including fumigatin chlorohydrin (1), whose configuration has not been reported before, and one new compound iso-fumigatin ...
Lu Wang   +9 more
doaj   +1 more source

Ontology-based knowledge representation of experiment metadata in biological data mining [PDF]

open access: yes, 2009
According to the PubMed resource from the U.S. National Library of Medicine, over 750,000 scientific articles have been published in the ~5000 biomedical journals worldwide in the year 2007 alone.
Burke, Squires   +12 more
core   +1 more source

Identification, Cloning and Heterologous Expression of the Gene Cluster Directing RES-701-3, -4 Lasso Peptides Biosynthesis from a Marine Streptomyces Strain

open access: yesMarine Drugs, 2020
RES-701-3 and RES-701-4 are two class II lasso peptides originally identified in the fermentation broth of Streptomyces sp. RE-896, which have been described as selective endothelin type B receptor antagonists. These two lasso peptides only differ in the
Daniel Oves-Costales   +3 more
doaj   +1 more source

Cis-regulatory module detection using constraint programming [PDF]

open access: yes, 2010
We propose a method for finding CRMs in a set of co-regulated genes. Each CRM consists of a set of binding sites of transcription factors. We wish to find CRMs involving the same transcription factors in multiple sequences.
Guns, Tias   +3 more
core   +1 more source

Genomic Mining for Aspergillus Natural Products

open access: yesChemistry & Biology, 2006
The genus Aspergillus is renowned for its ability to produce a myriad of bioactive secondary metabolites. Although the propensity of biosynthetic genes to form contiguous clusters greatly facilitates assignment of putative secondary metabolite genes in the completed Aspergillus genomes, such analysis cannot predict gene expression and, ultimately ...
Bok, Jin Woo   +5 more
openaire   +2 more sources

Genome Mining Reveals Two Missing CrtP and AldH Enzymes in the C30 Carotenoid Biosynthesis Pathway in Planococcus faecalis AJ003T

open access: yesMolecules, 2020
Planococcus faecalis AJ003T produces glycosyl-4,4′-diaponeurosporen-4′-ol-4-oic acid as its main carotenoid. Five carotenoid pathway genes were presumed to be present in the genome of P.
Jun Ho Lee, Jin Won Kim, Pyung Cheon Lee
doaj   +1 more source

MINTbase v2.0: a comprehensive database for tRNA-derived fragments that includes nuclear and mitochondrial fragments from all The Cancer Genome Atlas projects. [PDF]

open access: yes, 2018
MINTbase is a repository that comprises nuclear and mitochondrial tRNA-derived fragments (\u27tRFs\u27) found in multiple human tissues. The original version of MINTbase comprised tRFs obtained from 768 transcriptomic datasets.
Kirino, Yohei   +7 more
core   +1 more source

AGILE: an assembled genome mining pipeline

open access: yesBioinformatics, 2018
Abstract Summary A number of limiting factors mean that traditional genome annotation tools either fail or perform sub-optimally when trying to detect coding sequences in poor quality genome assemblies/genome reports.
Graham M Hughes, Emma C Teeling
openaire   +3 more sources

A large scale prediction of bacteriocin gene blocks suggests a wide functional spectrum for bacteriocins

open access: yes, 2015
Bacteriocins are peptide-derived molecules produced by bacteria, whose recently-discovered functions include virulence factors and signalling molecules as well as their better known roles as antibiotics.
Freed, Stefan D   +3 more
core   +1 more source

Android Malware Clustering through Malicious Payload Mining

open access: yes, 2017
Clustering has been well studied for desktop malware analysis as an effective triage method. Conventional similarity-based clustering techniques, however, cannot be immediately applied to Android malware analysis due to the excessive use of third-party ...
I Santos   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy