Results 111 to 120 of about 1,743,586 (380)

Antimicrobial antagonists against food pathogens; a bacteriocin perspective [PDF]

, 2015
peer-reviewedEfforts are continuing to find novel bacteriocins with enhanced specificity and potency. Traditional plating techniques are still being used for bacteriocin screening studies, however, the availability of ever more bacterial genome sequences
Cotter, Paul D., Hill, Colin, O'Connor, Paula M., Ross, R Paul   +3 more
core   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Complete Genome Sequence of Two Deep-Sea Streptomyces Isolates from Madeira Archipelago and Evaluation of Their Biosynthetic Potential

Marine Drugs, 2021
The deep-sea constitutes a true unexplored frontier and a potential source of innovative drug scaffolds. Here, we present the genome sequence of two novel marine actinobacterial strains, MA3_2.13 and S07_1.15, isolated from deep-sea samples (sediments ...
Pedro Albuquerque, Inês Ribeiro, Sofia Correia, Ana Paula Mucha, Paula Tamagnini, Andreia Braga-Henriques, Maria de Fátima Carvalho, Marta V. Mendes   +7 more
doaj   +1 more source

Infectious Disease Ontology [PDF]

, 2009
Technological developments have resulted in tremendous increases in the volume and diversity of the data and information that must be processed in the course of biomedical and clinical research and practice.
A Bresell, A Djebbari, A Doms, A Ruttenberg, A Valouev, AC Yu, B Grinde, B Smith, B Smith, B Smith, B Smith, B Zhang, BR Zeeberg, C Medigue, C Rosse, C Schonbach, C Wolting, CA Schurink, CH Kim, D Huang, D Pisanelli, DA Natale, DL Buckeridge, DL Buckeridge, DL Rubin, DL Rubin, DP Hill, E Camon, F Baader, G Grumbling, H Tveit, HM Muller, I Spasic, J Bard, J Chabalier, J Kohler, JA Blake, JA Lee, JD Osborne, JM Cherry, K Thursky, KL Rickard, KM Coonan, LT Detwiler, M Brameier, M Coleman, M Rajapakse, MF Ochs, N Guarino, N Tiffin, NC Ide, O Bodenreider, O Bodenreider, PL Whetzel, R Cornet, SA Racunas, SE Baranzini, SL Pestotnik, TG Veenema, V Sintchenko, W Ceusters, W Ceusters, W Ceusters   +62 more
core   +3 more sources

Transporter Protein-Guided Genome Mining for Head-to-Tail Cyclized Bacteriocins

Molecules, 2021
Head-to-tail cyclized bacteriocins are ribosomally synthesized antimicrobial peptides that are defined by peptide backbone cyclization involving the N- and C- terminal amino acids.
D. Major, Lara Flanzbaum, Leah Lussier, C. Davies, K. M. Caldo, J. Acedo   +5 more
semanticscholar   +1 more source

Machine Learning in Polymer Research

Advanced Materials, Volume 37, Issue 11, March 19, 2025.
Artificial intelligence (AI) has permeated every aspect of science, including polymer research. Researchers from both fields need to collaborate to understand the challenges and opportunities of each domain. This review is therefore written by mathematicians and polymer chemists to highlight the key research questions polymer chemists aim to address ...
Wei Ge, Ramindu De Silva, Yanan Fan, Scott A. Sisson, Martina H. Stenzel   +4 more
wiley   +1 more source

Molecular Mapping of Reduced Plant Height Gene Rht24 in Bread Wheat

Frontiers in Plant Science, 2017
Height is an important trait related to plant architecture and yield potential in bread wheat (Triticum aestivum L.). We previously identified a major quantitative trait locus QPH.caas-6A flanked by simple sequence repeat markers Xbarc103 and Xwmc256 ...
Xiuling Tian, Xiuling Tian, Weie Wen, Weie Wen, Li Xie, Luping Fu, Dengan Xu, Chao Fu, Desen Wang, Xinmin Chen, Xianchun Xia, Xianchun Xia, Quanjia Chen, Zhonghu He, Zhonghu He, Shuanghe Cao   +15 more
doaj   +1 more source

Genome Mining of Pseudomonas Species: Diversity and Evolution of Metabolic and Biosynthetic Potential

Molecules, 2021
Microbial genome sequencing has uncovered a myriad of natural products (NPs) that have yet to be explored. Bacteria in the genus Pseudomonas serve as pathogens, plant growth promoters, and therapeutically, industrially, and environmentally important ...
Khorshed Alam, Md. Mahmudul Islam, Caiyun Li, Sharmin Sultana, Lin Zhong, Qiyao Shen, Guangle Yu, Jinfang Hao, Youming Zhang, Ruijuan Li, Aiying Li   +10 more
doaj   +1 more source

ACSL1 Aggravates Thromboinflammation by LPC/LPA Metabolic Axis in Hyperlipidemia Associated Myocardial Ischemia‐Reperfusion Injury

Advanced Science, Volume 12, Issue 11, March 20, 2025.
In hyperlipidemic states, Long‐chain fatty acyl‐CoA synthetase 1 (ACSL1) is consistently induced, which then reprogrammes the lipid metabolism in monocytes. The accumulation of monocyte‐secreted lysophosphatidylcholine (LPC)/lysophosphatidic acid (LPA) enhances the thrombotic and inflammatory processes Then LPC/LPA axis promots activation and NETosis ...
Shuai Jiang, Xueguang Lin, Bo Chen, Gang Chen, Kristine J.S. Kwan, Jing Liu, Qi Sun, Jie Wang, Yijie Lu, Jindong Tong, Ying Deng, Bo Yu, Jingdong Tang   +12 more
wiley   +1 more source

Marine-Derived Streptomyces sennicomposti GMY01 with Anti-Plasmodial and Anticancer Activities: Genome Analysis, In Vitro Bioassay, Metabolite Profiling, and Molecular Docking

Microorganisms, 2023
To discover novel antimalarial and anticancer compounds, we carried out a genome analysis, bioassay, metabolite profiling, and molecular docking of marine sediment actinobacteria strain GMY01. The whole-genome sequence analysis revealed that Streptomyces
Jaka Widada, Ema Damayanti, Mustofa Mustofa, Achmad Dinoto, Rifki Febriansah, Triana Hertiani   +5 more
doaj   +1 more source