Results 181 to 190 of about 1,743,586 (380)
GeneHuggers: database mining and application connectivity tools for subsequence analyses of the human genome [PDF]
, 2003 Jason S. Iacovoni
openalex +1 more source
From parasite genomes to one healthy world: Are we having fun yet? [PDF]
, 2009 In 1990, the Human Genome Sequencing Project was established. This laid the ground work for an explosion of sequence data that has since followed. As a result of this effort, the first complete genome of an animal, Caenorhabditis elegans was published in
Gasbarre, Louis C., Zarlenga, Dante
core +1 more source
The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction
Advanced Science, EarlyView.Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang +8 more
wiley +1 more source
GFINDer: Genome Function INtegrated Discoverer through dynamic annotation, statistical analysis, and mining [PDF]
, 2004 Marco Masseroli +2 more
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Advanced Science, EarlyView.This review explores how multi‐omics, visualization technologies, and AI drive CAR‐T therapy from the micro to the macro level, from preclinical studies to clinical applications. The convergence of these approaches provides deeper insight into CAR‐T cell mechanisms, aids in structural optimization, and significantly enhances treatment efficacy and ...
Yuting Gong +4 more
wiley +1 more source
Database Transposition for Constrained (Closed) Pattern Mining [PDF]
Knowledge Discovery in Inductive Databases, Third International
Workshop, KDID 2004, Pisa, Italy, Septembre 2004, Revised Selected and
Invited Papers, Bart Goethals, Arno Siebes (Ed.) (2004) 89-107, 2009 Recently, different works proposed a new way to mine patterns in databases with pathological size. For example, experiments in genome biology usually provide databases with thousands of attributes (genes) but only tens of objects (experiments). In this case, mining the "transposed" database runs through a smaller search space, and the Galois connection
arxiv
Advanced Science, EarlyView.The presence of a micropapillary (MPP) component is critical for lung adenocarcinoma (LUAD) surgery, yet reliable blood biomarkers remain lacking. This study integrates proteomics for biomarker identification, a nanomixing‐enhanced surface‐enhanced Raman spectroscopy (SERS) platform for sensitive detection, and machine learning for accurate ...
Dechun Zhang +4 more
wiley +1 more source
Angewandte Chemie, EarlyView.Gromomycins represent a novel class of pentacyclic triterpene antibiotics with a unique biosynthetic pathway independent of the squalene route. These compounds exhibit potent activity against drug‐resistant Gram‐positive pathogens, including MRSA, and their unprecedented cyclization mechanism provides new insight into bacterial triterpene biosynthesis.
Stepan Tistechok +11 more
wiley +2 more sources
Type III Polyketide Synthase β-Ketoacyl-ACP Starter Unit and Ethylmalonyl-CoA Extender Unit Selectivity Discovered by Streptomyces coelicolor Genome Mining [PDF]
, 2006 Lijiang Song +8 more
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A Comparative Analysis of Ensemble Classifiers: Case Studies in Genomics [PDF]
arXiv, 2013 The combination of multiple classifiers using ensemble methods is increasingly important for making progress in a variety of difficult prediction problems. We present a comparative analysis of several ensemble methods through two case studies in genomics, namely the prediction of genetic interactions and protein functions, to demonstrate their efficacy
arxiv