Results 211 to 220 of about 1,743,586 (380)

Prospecting for natural products by genome mining and microcrystal electron diffraction

Nature Chemical Biology, 2021
Lee Joon Kim, M. Ohashi, Zhuan Zhang, D. Tan, M. Asay, D. Cascio, José A. Rodríguez, Yi Tang, H. Nelson   +8 more
semanticscholar   +1 more source

Data mining and the human genome

, 2000
Abstract : As genomics research moves from an era of data acquisition to one of both acquisition and interpretation, new methods are required for organizing and prioritizing the data. These methods would allow an initial level of data analysis to be carried out before committing resources to a particular genetic locus.
Steven Koonin, Freeman Dyson, Terence Hwa, Oscar Rothaus, Roy Schwitters, Christopher W. Stubbs, William Dally, Curtis G. Callan, Henry D. I. Abarbanel, Peter J. Weinberger, Herbert Levine   +10 more
openaire   +3 more sources

JCoast – A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes [PDF]

, 2008
Michael Richter, Thierry Lombardot, Ivaylo Kostadinov, Renzo Kottmann, Melissa B. Duhaime, Jörg Peplies, Frank Oliver Glöckner   +6 more
openalex   +1 more source

Starter unit specificity directs genome mining of polyketide synthase pathways in fungi [PDF]

, 2008
Jason M. Crawford, Anna L. Vagstad, Kenneth C. Ehrlich, Craig A. Townsend   +3 more
openalex   +1 more source

Editorial: The discovery of bioactive natural products: the isolation and structural elucidation, genome mining, OSMAC strategy, and biotransformation

Frontiers in Microbiology, 2023
Dewu Zhang, Kalindi Morgan, Ling Liu
doaj   +1 more source

Systematic Association of Genes to Phenotypes by Genome and Literature Mining

, 2005
Jan O. Korbel, Tobias Doerks, Lars Juhl Jensen, Carolina Perez‐Iratxeta, Szymon Kaczanowski, Sean Hooper, Miguel A. Andrade‐Navarro, Peer Bork   +7 more
openalex   +2 more sources

Genome Mining in Streptomyces. Discovery of an Unprecedented P450-Catalyzed Oxidative Rearrangement That Is the Final Step in the Biosynthesis of Pentalenolactone [PDF]

, 2011
Dongqing Zhu, Myung‐Ji Seo, Haruo Ikeda, David E. Cane   +3 more
openalex   +1 more source

Editorial: Trends in applications and improved production of biologically active metabolites using microbial fermentations

Frontiers in Microbiology, 2022
Niranjan Koirala, Ameer Khusro, Sailesh Malla   +2 more
doaj   +1 more source

The Comprehensive Phytopathogen Genomics Resource: a web-based resource for data-mining plant pathogen genomes [PDF]

, 2011
John P. Hamilton, Eric C Neeno-Eckwall, Bishwo N. Adhikari, Nicole T. Perna, Ned Tisserat, Jan E. Leach, C. André Lévesque, C. Robin Buell   +7 more
openalex   +1 more source

DBgDel: Database-Enhanced Gene Deletion Framework for Growth-Coupled Production in Genome-Scale Metabolic Models [PDF]

arXiv
When simulating metabolite productions with genome-scale constraint-based metabolic models, gene deletion strategies are necessary to achieve growth-coupled production, which means cell growth and target metabolite production occur simultaneously.
arxiv