Results 211 to 220 of about 176,908 (324)

Genome Mining and Marine Microbial Natural Products

, 2020
Dobson, Alan, Zhang, Changsheng, Hong, Kui   +2 more
openalex   +1 more source

Prioritising research on endocrine disruption in the marine environment: a global perspective

Biological Reviews, EarlyView.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto, Angelica Miglioli, Carlie A. LaLone, Lisa Baumann, Alice Baynes, Mélanie Blanc‐Legendre, Ibon Cancio, Xavier Cousin, ZhiChao Dang, Rémi Dumollard, Alex T. Ford, Christopher Green, Taisen Iguchi, Philippa Kearney, Thomas Knigge, Christophe Minier, Tiphaine Monsinjon, Marta S. Monteiro, Joachim Sturve, Haruna Watanabe, Hiroshi Yamamoto, Gerald Ankley, Deborah M. Power, Ioanna Katsiadaki   +23 more
wiley   +1 more source

Exploring the potential of Bacillus spp. for secondary metabolite production through genome mining approaches. [PDF]

J Genet Eng Biotechnol
Naser SR, Chowdhury SF, Sarkar MMH, Habib MA, Akter S, Banu TA, Goswami B, Khan MS.   +7 more
europepmc   +1 more source

Results of mining G. polyisoprenivorans, G. rubripertincta, and G. terrae genomes by the antiSMASH tool

, 2022
Jeysson Sánchez-Suárez
openalex   +2 more sources

Identification and Phylogenetic Characterisation of Novel Adeno‐Associated Virus Capsids in Non‐Human Primate Tissues

Cell Proliferation, EarlyView.
AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu, Kai Xu, Yali Ding, Kailun Liu, Jing Liu, Zongren Hou, Rui Niu, Ning Yang, Hualing Qin, Baoyang Hu, Ying Zhang, Wei Li   +11 more
wiley   +1 more source

RECC: A Red/ET-CRISPR/Cas9-based system enabling genome mining of marine <i>Pseudoalteromonas</i> for novel natural products. [PDF]

Synth Syst Biotechnol
Wang ZJ, Zhou H, Zhang Y, Yan F, Huo L, Wang X.   +5 more
europepmc   +1 more source

Integrated genome and metabolome mining unveiled structure and biosynthesis of novel lipopeptides from a deep‐sea Rhodococcus

Costanza Ragozzino, Fortunato Palma Esposito, Carmine Buonocore, Pietro Tedesco, Daniela Coppola, Davide Paccagnella, Nadine Ziemert, Gerardo Della Sala, Donatella de Pascale   +8 more
openalex   +1 more source

Evaluation of niche adaptation features by genome data mining approach of Escherichia coli urinary and gastrointestinal strains

, 2019
Thiago GS Paim, Gustavo Enck Sambrano, Keli Cristine Reiter, Fernando Hayashi Sant’Anna, Renata Oliveira Soares, Mariana Preussler Mott, Samuel Paulo Cibulski, Pedro Alves d’Azevedo   +7 more
openalex   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Toward the Bioremediation of Nylon Waste Materials: Genome Mining Leads to the Identification of a Thermostable Laurolactamase From Thermopolyspora flexuosa. [PDF]

ChemSusChem
Cleveland ME, Bunyat-Zada AR, Hoffman ER, Howe GW.   +3 more
europepmc   +1 more source