Results 251 to 260 of about 1,743,586 (380)

Mining meiosis with genomic models [PDF]

Nature Reviews Genetics, 2006
Ranganath, R.M., Venkatachalaiah, G.
openaire   +1 more source

Mining Thermophile Genomes for New PETases with Exceptional Thermostabilities Using Sequence Similarity Networks

ChemBioChem, EarlyView.
Targeted genome mining identified thermostable enzymes (PETases) that hydrolyze the commonly used plastic polymer polyethylene terephthalate (PET). Thermostable enzymes are identified from thermophilic microbial sources. Experimental results reveal enzymatic activity on authentic PET films, highlighting potential for industrial application.
Zhenyu Hu, Kody Klupt, David L. Zechel, Zongchao Jia, Graeme Howe   +4 more
wiley   +1 more source

Genome mining and metabolite profiling illuminate the taxonomy status and the cytotoxic activity of a mangrove-derived Microbacterium alkaliflavum sp. nov. [PDF]

BMC Microbiol
Hu WJ, Deng LX, Huang YY, Wang XC, Qing JL, Zhu HJ, Zhou X, Zhou XY, Chu JM, Pan X.   +9 more
europepmc   +1 more source

Genome Mining for Radical SAM Protein Determinants Reveals Multiple Sactibiotic-Like Gene Clusters

, 2011
Kiera Murphy, Órla O’Sullivan, Mary C. Rea, Paul D. Cotter, R. Paul Ross, Colin Hill   +5 more
openalex   +2 more sources

Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria [PDF]

, 2014
Anne‐Catrin Letzel, Sacha J. Pidot, Christian Hertweck   +2 more
openalex   +1 more source

Clade III Synthases Add Cyclic And Linear Terpenoids To The Psilocybe Metabolome

ChemBioChem, Accepted Article.
Psilocybe “magic mushrooms” are best known for their indolethylamine psilocybin, yet they encode enzymes for a much more diverse arsenal of small and potentially bioactive molecules. Here, we report on four Psilocybe cubensis clade III sesquiterpene synthases, CubB‐CubE, whose genes are differently expressed in fruiting bodies compared to vegetative ...
Nick Zschoche, Sebastian Schober, Karl Walther, Andrew R. Chadeayne, Markus Gressler, Stefan Bartram, Sarah E. O'Connor, Dirk Hoffmeister   +7 more
wiley   +1 more source

PhyloMarker—A Tool for Mining Phylogenetic Markers Through Genome Comparison: Application of the Mouse Lemur (Genus Microcebus) Phylogeny

Evolutionary Bioinformatics, 2012
Guoqing Lu, Runhua Lei, Thaine W. Rowley, Mary C. Christman, George H. Perry, Edward E. Louis Jr, Lifeng Zhu, Carolyn A. Bailey, Shannon E. Engberg, Mindy L. Wood   +9 more
doaj  

Metabolic Blockade-Based Genome Mining of <i>Malbranchea circinata</i> SDU050: Discovery of Diverse Secondary Metabolites. [PDF]

Mar Drugs
Yang H, Luo X, Shang Z, Li K, Cai J, Chen Y, Xin L, Ju J.   +7 more
europepmc   +1 more source

Genome Sequence of Desulfosporosinus sp. OT, an Acidophilic Sulfate-Reducing Bacterium from Copper Mining Waste in Norilsk, Northern Siberia

, 2011
Helge K. Abicht, Stefano Mancini, Olga V. Karnachuk, Marc Solioz   +3 more
openalex   +1 more source

Biosynthesis of the fungal cyclic lipodepsipeptide pleosporacin, a new selective inhibitor of the phytopathogen Botrytis cinerea

ChemBioChem, Accepted Article.
Bioactivity‐guided isolation led to the identification of the cyclic lipodepsipeptide pleosporacin (1) from the mycelia extract of fungal strain Pleosporales sp. IBWF 020‐21, a potent selective inhibitor of the fungal phytopathogen Botrytis cinerea. The structure and stereochemistry of 1 were elucidated by NMR and Marfey analysis, respectively.
Carsten Wieder, Rainer Wiechert, Alexander Yemelin, Louis Pergaud Sandjo, Eckhard Thines, Till Opatz, Anja Schüffler   +6 more
wiley   +1 more source