Results 271 to 280 of about 1,743,586 (380)

Discovering new hub genes of dilated cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified. The present study aimed to explore new hub genes of DCM by mining the human DCM databases and further by experimental validation.
Jun‐Yan Zhu, Yu Han, Jing‐Yu Yang, De‐Ping Wang, Li‐Juan Gao, Teng Sun, Yan‐Lin Feng, Zhong‐Mei He, Bin Zhou, Ji‐Min Cao   +9 more
wiley   +1 more source

Genome mining shows that retroviruses are pervasively invading vertebrate genomes. [PDF]

Nat Commun, 2023
Wang J, Han GZ.
europepmc   +1 more source

Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae

, 2012
Christiane Wallwey, Christoph Heddergott, Xiulan Xie, Axel A. Brakhage, Shu‐Ming Li   +4 more
openalex   +1 more source

Genome mining strategies for ribosomally synthesised and post-translationally modified peptides

Computational and Structural Biotechnology Journal, 2020
Alicia H. Russell, A. Truman
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Fragment-Guided Genome Mining of Octacyclic Cyclophane Alkaloids from Fungi. [PDF]

J Am Chem Soc
Zhang Y, Wu L, Kerr TA, Garg NK, Tang Y.
europepmc   +1 more source

Genome mining conformance to metabolite profile of Bacillus strains to control potato pathogens. [PDF]

Sci Rep, 2023
Lagzian A, Riseh RS, Sarikhan S, Ghorbani A, Khodaygan P, Borriss R, Guzzi PH, Veltri P.   +7 more
europepmc   +1 more source

Computational Mining and Genome Wide Distribution of Microsatellite in Fusarium oxysporum f. sp. lycopersici

, 2012
Sudheer Kumar, Deepak Kumar Maurya, Shalini Rai, Prem Lal Kashyap, Alok Kumar Srivastava   +4 more
openalex   +2 more sources

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Genome Mining of <i>Pseudarthrobacter</i> sp. So.54, a Rhizospheric Bacteria from <i>Colobanthus quitensis</i> Antarctic Plant. [PDF]

Biomolecules
González D, Bruna P, Contreras MJ, Leal K, Urrutia CV, Núñez-Montero K, Barrientos L.   +6 more
europepmc   +1 more source