Results 71 to 80 of about 105,282 (228)

A large scale prediction of bacteriocin gene blocks suggests a wide functional spectrum for bacteriocins

open access: yes, 2015
Bacteriocins are peptide-derived molecules produced by bacteria, whose recently-discovered functions include virulence factors and signalling molecules as well as their better known roles as antibiotics.
Freed, Stefan D   +3 more
core   +1 more source

Overview of Random Forest Methodology and Practical Guidance with Emphasis on Computational Biology and Bioinformatics [PDF]

open access: yes, 2012
The Random Forest (RF) algorithm by Leo Breiman has become a standard data analysis tool in bioinformatics. It has shown excellent performance in settings where the number of variables is much larger than the number of observations, can cope with ...
Boulesteix, Anne-Laure   +3 more
core   +1 more source

Genome mining shows that retroviruses are pervasively invading vertebrate genomes

open access: yesNature Communications, 2023
AbstractEndogenous retroviruses (ERVs) record past retroviral infections, providing molecular archives for interrogating the evolution of retroviruses and retrovirus-host interaction. However, the vast majority of ERVs are not active anymore due to various disruptive mutations, and ongoing retroviral invasion of vertebrate genomes has been rarely ...
Jianhua Wang, Guan-Zhu Han
openaire   +3 more sources

U‐Shaped Response of Flowering Time to Low and High Nitrogen via a Transcription Feedback Loop in Rice

open access: yesAdvanced Science, EarlyView.
The “seesaw effect” of Nhd1‐Ghd7 module in regulating flowering time (days to heading in rice) responses to nitrogen (N) via Hd3a/RFT1: deficient‐N (DN) delays flowering via Ghd7‐mediated suppression of Nhd1; moderate‐N (MN) impairs this suppression, enhancing Nhd1 to promote flowering; whereas superior‐N (SN) delays flowering by Nhd1‐activated ...
Shunan Zhang   +12 more
wiley   +1 more source

Genomic and Transcriptomic Approaches Provide a Predictive Framework for Sesquiterpenes Biosynthesis in Desarmillaria tabescens CPCC 401429

open access: yesJournal of Fungi, 2023
Terpenoids constitute a structurally diverse class of secondary metabolites with wide applications in the pharmaceutical, fragrance and flavor industries.
Tao Zhang   +10 more
doaj   +1 more source

De Novo Assembly of Nucleotide Sequences in a Compressed Feature Space [PDF]

open access: yes, 2017
Sequencing technologies allow for an in-depth analysis of biological species but the size of the generated datasets introduce a number of analytical challenges.
Robertson, David L., Tapinos, Avraam
core   +1 more source

Mining the chicken genome [PDF]

open access: yesGenome Biology, 2002
The chicken EST repository gives access to a BLAST server dedicated to mining recently released sequence information from the chick large-scale expressed sequence tag (EST ...
openaire   +1 more source

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

open access: yesAdvanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang   +13 more
wiley   +1 more source

Genomic and Physiological Characterization of Bacilli Isolated From Salt-Pans With Plant Growth Promoting Features

open access: yesFrontiers in Microbiology, 2021
Massive application of chemical fertilizers and pesticides has been the main strategy used to cope with the rising crop demands in the last decades. The indiscriminate use of chemicals while providing a temporary solution to food demand has led to a ...
Claudia Petrillo   +11 more
doaj   +1 more source

Extraction of Transcript Diversity from Scientific Literature [PDF]

open access: yes, 2005
Transcript diversity generated by alternative splicing and associated mechanisms contributes heavily to the functional complexity of biological systems.
Lars J Jensen   +4 more
core   +6 more sources

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