Results 1 to 10 of about 5,189,630 (339)

3D genome organization [PDF]

Scientific Reports, 2022
Our genomes are highly organized spatially in three-dimensions (3D). In interphase nuclei, the genome is anchored and regulated by various nuclear scaffolds and structures, including the nuclear lamina at the nuclear edge, and nucleoli located more ...
Asli Silahtaroglu, Joanna M. Bridger, Elissa P. Lei   +2 more
doaj   +6 more sources

Chromosome Architecture and Genome Organization. [PDF]

PLoS ONE, 2015
How the same DNA sequences can function in the three-dimensional architecture of interphase nucleus, fold in the very compact structure of metaphase chromosomes and go precisely back to the original interphase architecture in the following cell cycle ...
Giorgio Bernardi
doaj   +4 more sources

The mixed liver and kidney transcriptome dataset of Darevskia valentini rock lizard

BMC Research Notes, 2022
Objectives This study is performed in the frame of a bigger study dedicated to genomics and transcriptomics of parthenogenesis in vertebrates. Among vertebrates, obligate parthenogenesis was first described in the lizards of the genus Darevskia.
Sergei S. Ryakhovsky, Daria V. Zhernakova, Vitaly I. Korchagin, Andrey A. Vergun, Anastasiya E. Girnyk, Victoria A. Dikaya, Marine S. Arakelyan, Aleksey S. Komissarov, Alexey P. Ryskov   +8 more
doaj   +1 more source

Transposable elements that have recently been mobile in the human genome

BMC Genomics, 2021
Background Transposable elements (TE) comprise nearly half of the human genome and their insertions have profound effects to human genetic diversification and as well as disease.
Matias I. Autio, Talal Bin Amin, Arnaud Perrin, Jen Yi Wong, Roger S.-Y. Foo, Shyam Prabhakar   +5 more
doaj   +1 more source

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. [PDF]

, 2020
Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Acevedo, David, Beliveau, Brian, Cavalli, Giacomo, KARPEN, Gary H., Lee, Yuh, Martins, Nuno, Ogiyama, Yuki, Wu, C-Ting   +7 more
core   +3 more sources

Origin, clonal diversity, and evolution of the parthenogenetic lizard Darevskia unisexualis

BMC Genomics, 2020
Background The hybridization of female D. raddei and male D. valentini gave rise to the parthenogenetic Caucasian rock lizard Darevskia unisexualis. A previously identified genetic polymorphism in the species consisted of one common and two allozyme ...
Andrey A. Vergun, Anastasiya E. Girnyk, Vitaly I. Korchagin, Seraphima K. Semyenova, Marine S. Arakelyan, Felix D. Danielyan, Robert W. Murphy, Alexey P. Ryskov   +7 more
doaj   +1 more source

Genome tectonics: linking dynamic genome organization with cellular nutrient

Lifestyle Genomics, 2022
Background: Our daily intake of food provides nutrients for the maintenance of health, growth and development. The field of nutrigenomics aims to link dietary intake/nutrients to changes in epigenetic status and gene expression.
Morgan Fleming, Fina Nelson, Iain Wallace, Christopher H. Eskiw   +3 more
doaj   +1 more source

Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer’s disease risk

Translational Psychiatry, 2021
Alzheimer’s disease (AD) has no cure, but early detection and risk prediction could allow earlier intervention. Genetic risk factors may differ between ethnic populations.
Daichi Shigemizu, Risa Mitsumori, Shintaro Akiyama, Akinori Miyashita, Takashi Morizono, Sayuri Higaki, Yuya Asanomi, Norikazu Hara, Gen Tamiya, Kengo Kinoshita, Takeshi Ikeuchi, Shumpei Niida, Kouichi Ozaki   +12 more
doaj   +1 more source

Plant genetic reseources: effective utilization [PDF]

, 2010
Characterizing better understanding the genome organization and differentiating identity of genotypes based on their morphology and genome characteristics are vital determinants in their commercialization, management of germplasm repositories, and ...
Budak, Hikmet
core   +1 more source

Multiple interspecific hybridization and microsatellite mutations provide clonal diversity in the parthenogenetic rock lizard Darevskia armeniaca

BMC Genomics, 2018
Background The parthenogenetic Caucasian rock lizard Darevskia armeniaca, like most other parthenogenetic vertebrate species, originated through interspecific hybridization between the closely related sexual Darevskia mixta and Darevskia valentini ...
Anastasiya E. Girnyk, Andrey A. Vergun, Seraphima K. Semyenova, Andrei S. Guliaev, Marine S. Arakelyan, Felix D. Danielyan, Irena A. Martirosyan, Robert W. Murphy, Alexey P. Ryskov   +8 more
doaj   +1 more source