Results 1 to 10 of about 1,131,441 (186)

100K Pathogen Genome Project. [PDF]

open access: yesGenome Announc, 2017
The 100K Pathogen Genome Project is producing draft and closed genome sequences from diverse pathogens. This project expanded globally to include a snapshot of global bacterial genome diversity.
Weimer BC.
europepmc   +3 more sources

The Helicobacter pylori Genome Project: insights into H. pylori population structure from analysis of a worldwide collection of complete genomes. [PDF]

open access: greenNat Commun, 2023
Thorell K   +10 more
europepmc   +2 more sources

Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background Fetal hemoglobin (HbF) induction has shown promise for the treatment of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective hematopoiesis and thus terminate transfusion dependency for formerly transfusion dependant ...
Noha Hamdy Eltaweel   +4 more
doaj   +1 more source

Characterization of tumor-associated reactive astrocytes in gliomas by single-cell and bulk tumor sequencing

open access: yesFrontiers in Neurology, 2023
ObjectiveAstrocytes constitute approximately 30% of cells in gliomas and play important roles in synapse construction and survival. Recently, JAK/STAT pathway activation associated with a new type of astrocyte was reported.
Chuan-bao Zhang   +9 more
doaj   +1 more source

Towards the Physical Map of the Trypanosoma cruzi Nuclear Genome: Construction of YAC and BAC Libraries of the Reference Clone T. cruzi CL-Brener [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 1997
Strategies to construct the physical map of the Trypanosoma cruzi nuclear genome have to capitalize on three main advantages of the parasite genome, namely (a) its small size, (b) the fact that all chromosomes can be defined, and many of them can be ...
I Ferrari   +31 more
doaj   +1 more source

Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines

open access: yesScientific Reports, 2021
Hepatitis B (HB) vaccines (Heptavax-II and Bimmugen) designed based on HBV genotypes A and C are mainly used for vaccination against HB in Japan. To determine whether there are differences in the genetic background associated with vaccine responsiveness,
Nao Nishida   +23 more
doaj   +1 more source

The Deep Genome Project [PDF]

open access: yesGenome Biology, 2020
K. C. Kent Lloyd   +43 more
doaj   +2 more sources

Genome-wide copy number variation analysis of hepatitis B infection in a Japanese population

open access: yesHuman Genome Variation, 2021
Hepatitis B: Gene copy numbers associated with risk of infection The risk of contracting the hepatitis B virus may be linked to the number of copies of certain genes in an individual’s genome.
Masataka Kikuchi   +7 more
doaj   +1 more source

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