Results 1 to 10 of about 549,745 (292)
Data Management for High-Throughput Genomics [PDF]
arXiv, 2009 Today's sequencing technology allows sequencing an individual genome within a few weeks for a fraction of the costs of the original Human Genome project. Genomics labs are faced with dozens of TB of data per week that have to be automatically processed and made available to scientists for further analysis.
arxiv
Haematologica, 2015 Prognostic stratification is critical for making therapeutic decisions and maximizing survival of patients with acute myeloid leukemia. Advances in the genomics of acute myeloid leukemia have identified several recurrent gene mutations whose prognostic ...
Niccolò Bolli +17 more
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Genome project faces commercialization test [PDF]
, 1992 Christopher Anderson, Peter Aldhous
openalex +1 more source
Revisiting olfactory receptors as putative drivers of cancer [version 1; referees: 2 approved]
Wellcome Open Research, 2017 BACKGROUND: Olfactory receptors (ORs) recognize odorant molecules and activate a signal transduction pathway that ultimately leads to the perception of smell.
Marco Ranzani +6 more
doaj +1 more source
Analysis of Metagenome Composition by the Method of Random Primers [PDF]
arXiv, 2016 Metagenome, a mixture of different genomes (as a rule, bacterial), represents a pattern, and the analysis of its composition is, currently, one of the challenging problems of bioinformatics. In the present study, the possibility of evaluating metagenome composition by DNA-marker methods is investigated.
arxiv
Inference of gene loss rates after whole genome duplications at early vertebrates through ancient genome reconstructions [PDF]
arXiv, 2018 The famous 2R hypothesis was first proposed by Susumu Ohno in 1970. It states that the two whole genome duplications had shaped the genome of early vertebrates. The most convincing evidence for 2R hypothesis comes from the 4:1 ratio chromosomal regions that have preserved both gene content and order in vertebrates compared with closely related. However,
arxiv
Survival-supervised latent Dirichlet allocation models for genomic analysis of time-to-event outcomes [PDF]
arXiv, 2012 Two challenging problems in the clinical study of cancer are the characterization of cancer subtypes and the classification of individual patients according to those subtypes. Statistical approaches addressing these problems are hampered by population heterogeneity and challenges inherent in data integration across high-dimensional, diverse covariates.
arxiv
Scientific ReportsThe neocortical development process includes cell proliferation, differentiation, migration, and maturation, supported by precise genetic regulation. To understand these processes at the cellular and molecular levels, it is necessary to characterize the ...
Yuichiro Hara +6 more
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