Results 1 to 10 of about 690,156 (316)

Genomic patterns of progression in smoldering multiple myeloma

Nature Communications, 2018
Smoldering MM (SMM) is a premalignant stage of multiple myeloma (MM). Here the authors perform whole genome sequencing of unique paired samples of SMM progressing to MM, and show that the genomic landscape at the SMM stage is very similar to MM, but ...
Niccolò Bolli, Francesco Maura, Stephane Minvielle, Dominik Gloznik, Raphael Szalat, Anthony Fullam, Inigo Martincorena, Kevin J. Dawson, Mehmet Kemal Samur, Jorge Zamora, Patrick Tarpey, Helen Davies, Mariateresa Fulciniti, Masood A. Shammas, Yu Tzu Tai, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth Anderson, Ludmil Alexandrov, David C. Wedge, Herve Avet-Loiseau, Peter Campbell, Nikhil Munshi   +23 more
doaj   +1 more source

Personal genomes in progress: from the Human Genome Project to the Personal Genome Project

Dialogues in Clinical Neuroscience, 2010
The cost of a diploid human genome sequence has dropped from about $70M to $2000 since 2007--even as the standards for redundancy have increased from 7x to 40x in order to improve call rates. Coupled with the low return on investment for common single-nucleotide polylmorphisms, this has caused a significant rise in interest in correlating genome ...
Lunshof, J., Bobe, J., Aach, J., Angrist, M., Thakuria, J., Vorhaus, D., Hoehe, M., Church, G.   +7 more
openaire   +5 more sources

LEGAL AND ETHICAL ASPECTS OF THE PARTICIPATION OF PERSONS WITH RESTRICTED ACTIVE LEGAL CAPACITY IN GENOME STUDIES [PDF]

Trames, 2004
Ülle Krikmann, Krista Kruuv, Marju Herodes, Tarmo Sild, Marika Žmenja, Tiina Talvik, Arvo Tikk   +6 more
doaj   +1 more source

Genome-wide association study of common side effects following COVID-19 booster vaccination in a cohort of corporate employees in Japan

Scientific Reports
Individual differences have been observed in side effects after vaccination for COVID-19, and host genetic factors have been suggested as a contributing factor.
Yosuke Omae, Seik-Soon Khor, Mihoko Shimada, Yosuke Kawai, Taihei Yamaguchi, Maiko Yagi, Masashi Ebisawa, Junko S. Takeuchi, Tetsuya Mizoue, Wataru Sugiura, Katsushi Tokunaga   +10 more
doaj   +1 more source

The Human Genome Organisation (HUGO) and a vision for Ecogenomics: the Ecological Genome Project. [PDF]

Hum Genomics, 2023
Capps B, Chadwick R, Lederman Z, Lysaght T, Mills C, Mulvihill JJ, Oetting WS, Winship I, HUGO Committee on Ethics, Law and Society.   +9 more
europepmc   +1 more source

The spatial transcriptome of the late-stage embryonic and postnatal mouse brain reveals spatiotemporal molecular markers

Scientific Reports
The neocortical development process includes cell proliferation, differentiation, migration, and maturation, supported by precise genetic regulation. To understand these processes at the cellular and molecular levels, it is necessary to characterize the ...
Yuichiro Hara, Takuma Kumamoto, Naoko Yoshizawa-Sugata, Kumiko Hirai, Xianghe Song, Hideya Kawaji, Chiaki Ohtaka-Maruyama   +6 more
doaj   +1 more source

Wilson disease (novel ATP7B variants) with concomitant FLNC-related cardiomyopathy

Human Genome Variation
We report a case of Wilson disease (WD) with dilated cardiomyopathy in which whole-genome sequencing (WGS) revealed the rare co-occurrence of two novel compound heterozygous ATP7B pathogenic variants (NM_001005918.3:c.2250del/p.N751Tfs*9 and c.3496C>T/p ...
Takeshi Imai, Satomi Mitsuhashi, Kenji Isahaya, Soichiro Shibata, Yosuke Kawai, Yosuke Omae, Katsushi Tokunaga, NCBN Controls WGS Consortium, Yoshihisa Yamano   +8 more
doaj   +1 more source

Harvesting the fruits of the first stage of the Primate Genome Project. [PDF]

Zool Res, 2023
Guo YT, Shao Y, Bi X, Zhang BL, Wu H, Zhou Y, Li ML, Yu L, Zhang G, Wu DD, Qi XG.   +10 more
europepmc   +1 more source

Russian genome project [PDF]

Nature, 1995
openaire   +2 more sources

Initiation of the Primate Genome Project. [PDF]

Zool Res, 2022
Wu DD, Qi XG, Yu L, Li M, Liu ZJ, Yoder AD, Roos C, Hayakawa T, Rogers J, Marques-Bonet T, Su B, Yao YG, Zhang YP, Zhang G.   +13 more
europepmc   +1 more source