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Genome Biology, 2020 In vivo research is critical to the functional dissection of multi-organ systems and whole organism physiology, and the laboratory mouse remains a quintessential animal model for studying mammalian, especially human, pathobiology. Enabled by technological innovations in genome sequencing, mutagenesis and genome editing, phenotype analyses, and ...
K. C. Kent Lloyd +43 more
doaj +14 more sources
The International Human Genome Project [PDF]
Human Molecular Genetics, 2021 The human genome project was conceived and executed as an international project, due to both pragmatic and principled reasons. This internationality has served the project well, with the resulting human genome being freely available for all researchers ...
Ewan Birney, Birney Ewan
exaly +3 more sources
The Helicobacter pylori Genome Project: insights into H. pylori population structure from analysis of a worldwide collection of complete genomes. [PDF]
Nat Commun, 2023 Helicobacter pylori, a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to the development of genetically distinct H.
Thorell K +10 more
europepmc +2 more sources
Beyond the Human Genome Project: The Age of Complete Human Genome Sequences and Pangenome References. [PDF]
Annu Rev Genomics Hum GenetThe Human Genome Project was an enormous accomplishment, providing a foundation for countless explorations into the genetics and genomics of the human species.
Taylor DJ +10 more
europepmc +2 more sources
The Human Genome Project changed everything. [PDF]
Nat Rev Genet, 2020 Thirty years on from the launch of the Human Genome Project, Richard Gibbs reflects on the promises that this voyage of discovery bore. Its success should be measured by how this project transformed the rules of research, the way of practising biological
Gibbs RA.
europepmc +2 more sources
Korean Genome Project: 1094 Korean personal genomes with clinical information. [PDF]
Sci Adv, 2020 The initial phase of the Korean Genome Project (Korea1K) releases 1094 whole genomes, along with data of 79 clinical traits. We present the initial phase of the Korean Genome Project (Korea1K), including 1094 whole genomes (sequenced at an average depth ...
Jeon S +28 more
europepmc +2 more sources
100K Pathogen Genome Project. [PDF]
Genome Announc, 2017 The 100K Pathogen Genome Project is producing draft and closed genome sequences from diverse pathogens. This project expanded globally to include a snapshot of global bacterial genome diversity.
Weimer BC.
europepmc +2 more sources
A 1000 Arab genome project to study the Emirati population. [PDF]
J Hum Genet, 2018 Discoveries from the human genome, HapMap, and 1000 genome projects have collectively contributed toward the creation of a catalog of human genetic variations that has improved our understanding of human diversity. Despite the collegial nature of many of
Al-Ali M, Osman W, Tay GK, AlSafar HS.
europepmc +2 more sources
The Chlamydomonas genome project: a decade on [PDF]
Trends in Plant Science, 2014 The green alga Chlamydomonas reinhardtii is a popular unicellular organism for studying photosynthesis, cilia biogenesis, and micronutrient homeostasis. Ten years since its genome project was initiated an iterative process of improvements to the genome and gene predictions has propelled this organism to the forefront of the omics era.
Blaby, IK +19 more
openaire +7 more sources
The rice genome annotation project: an updated database for mining the rice genome
Nucleic Acids ResearchRice (Oryza sativa L.) is a major cereal crop that provides calories across the world. With a small genome, rice has been used extensively as a model for genetic and genomic studies in the Poaceae.
Chenxin Li +2 more
exaly +2 more sources