Results 1 to 10 of about 1,112,525 (229)

The Deep Genome Project. [PDF]

Genome Biol, 2020
In vivo research is critical to the functional dissection of multi-organ systems and whole organism physiology, and the laboratory mouse remains a quintessential animal model for studying mammalian, especially human, pathobiology. Enabled by technological innovations in genome sequencing, mutagenesis and genome editing, phenotype analyses, and ...
Lloyd KCK, Adams DJ, Baynam G, Beaudet AL, Bosch F, Boycott KM, Braun RE, Caulfield M, Cohn R, Dickinson ME, Dobbie MS, Flenniken AM, Flicek P, Galande S, Gao X, Grobler A, Heaney JD, Herault Y, de Angelis MH, Lupski JR, Lyonnet S, Mallon AM, Mammano F, MacRae CA, McInnes R, McKerlie C, Meehan TF, Murray SA, Nutter LMJ, Obata Y, Parkinson H, Pepper MS, Sedlacek R, Seong JK, Shiroishi T, Smedley D, Tocchini-Valentini G, Valle D, Wang CL, Wells S, White J, Wurst W, Xu Y, Brown SDM.   +43 more
europepmc   +13 more sources

Initiation of the Primate Genome Project. [PDF]

Zool Res, 2022
This work was supported by the National Natural Science Foundation of China (31822048) and Strategic Priority Research Program of the Chinese Academy of Sciences (XDPB17)
Wu DD, Qi XG, Yu L, Li M, Liu ZJ, Yoder AD, Roos C, Hayakawa T, Rogers J, Marques-Bonet T, Su B, Yao YG, Zhang YP, Zhang G.   +13 more
europepmc   +9 more sources

100K Pathogen Genome Project. [PDF]

Genome Announc, 2017
The 100K Pathogen Genome Project is producing draft and closed genome sequences from diverse pathogens. This project expanded globally to include a snapshot of global bacterial genome diversity.
Weimer BC.
europepmc   +3 more sources

The Chlamydomonas genome project: A decade on [PDF]

Trends in Plant Science, 2014
The green alga Chlamydomonas reinhardtii is a popular unicellular organism for studying photosynthesis, cilia biogenesis, and micronutrient homeostasis.
Aksoy, M, Blaby, IK, Blaby-Haas, CE, Dutcher, S, Goodstein, D, Grimwood, J, Grossman, A, Harris, EH, Hom, EFY, King, S, Lopez, D, Merchant, SS, Porter, M, Prochnik, S, Schmutz, J, Stanke, M, Tourasse, N, Umen, J, Vallon, O, Witman, GB   +19 more
core   +9 more sources

The humane genome project [PDF]

Nature Genetics, 2000
Geoffrey D. Carr
openalex   +4 more sources

Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia

Journal of Genetic Engineering and Biotechnology, 2021
Background Fetal hemoglobin (HbF) induction has shown promise for the treatment of β-hemoglobinopathies. HbF induction in β-thalassemia could overcome ineffective hematopoiesis and thus terminate transfusion dependency for formerly transfusion dependant ...
Noha Hamdy Eltaweel, Ghada Youssef ElKamah, Rabab Khairat, Hanan Abd Elmawgoud Atia, Khalda S. Amr   +4 more
doaj   +1 more source

Characterization of tumor-associated reactive astrocytes in gliomas by single-cell and bulk tumor sequencing

Frontiers in Neurology, 2023
ObjectiveAstrocytes constitute approximately 30% of cells in gliomas and play important roles in synapse construction and survival. Recently, JAK/STAT pathway activation associated with a new type of astrocyte was reported.
Chuan-bao Zhang, Chuan-bao Zhang, Zhi-liang Wang, Zhi-liang Wang, Han-jie Liu, Han-jie Liu, Zheng Wang, Zheng Wang, Wang Jia, Wang Jia   +9 more
doaj   +1 more source

The Feline Genome Project [PDF]

Annual Review of Genetics, 2002
▪ Abstract  The compilation of a dense gene map and eventually a whole genome sequence (WGS) of the domestic cat holds considerable value for human genome annotation, for veterinary medicine, and for insight into the evolution of genome organization among mammals.
O'Brien, Stephen J., Menotti-Raymond, Marilyn, Murphy, William J., Yuhki, Naoya   +3 more
openaire   +3 more sources

Towards the Physical Map of the Trypanosoma cruzi Nuclear Genome: Construction of YAC and BAC Libraries of the Reference Clone T. cruzi CL-Brener [PDF]

Memorias do Instituto Oswaldo Cruz, 1997
Strategies to construct the physical map of the Trypanosoma cruzi nuclear genome have to capitalize on three main advantages of the parasite genome, namely (a) its small size, (b) the fact that all chromosomes can be defined, and many of them can be ...
I Ferrari, H Lorenzi, MR Santos, S Brandariz, JM Requena, A Schijman, M Vázquez, JF da Silveira, C Ben-Dov, C Medrano, S Ghío, P López Bergami, I Cano, B Zingales, TP Urmenyi, E Rondinelli, A González, A Cortes, MC Lopez, MC Thomas, C Alonso, JL Ramírez, MA Chiurrillo, R Rangel Aldao, A Brandão, W Degrave, V Perrot, M Saumier, A Billaut, D Cohen, D Le Paslier, MJ Levin   +31 more
doaj   +1 more source

Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines

Scientific Reports, 2021
Hepatitis B (HB) vaccines (Heptavax-II and Bimmugen) designed based on HBV genotypes A and C are mainly used for vaccination against HB in Japan. To determine whether there are differences in the genetic background associated with vaccine responsiveness,
Nao Nishida, Masaya Sugiyama, Jun Ohashi, Yosuke Kawai, Seik-Soon Khor, Sohji Nishina, Kazumi Yamasaki, Hirohisa Yazaki, Kaori Okudera, Akihiro Tamori, Yuichiro Eguchi, Aiko Sakai, Keisuke Kakisaka, Hiromi Sawai, Takayo Tsuchiura, Miyuki Ishikawa, Keisuke Hino, Ryo Sumazaki, Yasuhiro Takikawa, Tatsuo Kanda, Osamu Yokosuka, Hiroshi Yatsuhashi, Katsushi Tokunaga, Masashi Mizokami   +23 more
doaj   +1 more source