Results 31 to 40 of about 85,734 (198)

Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae

eLife, 2020
Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a Saccharomyces cerevisiae genetic system that generates gross chromosomal rearrangements (GCRs) mediated by foldback ...
Bin-zhong Li, Christopher D Putnam, Richard David Kolodner   +2 more
doaj   +1 more source

Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution [PDF]

, 2010
Chromosomal rearrangements and copy number variants (CNVs) play key roles in genome evolution and genetic disease; however, the molecular mechanisms underlying these types of structural genomic variation are not fully understood.
Skinner, Benjamin M., Bunzey, Sydney K., Ellegren, Hans, Völker, Martin, Backström, Niclas, Langley, Elizabeth J, Griffin, Darren K.   +6 more
core   +1 more source

An intelligent recognition method of chromosome rearrangement patterns based on information entropy

Scientific Reports, 2022
Chromosome rearrangements play an important role in the speciation of plants and animals, and the recognition of chromosome rearrangement patterns is helpful to elucidate the mechanism of species differentiation at the chromosome level.
Fushun Wang, Ruolan Zhang, Xiaohua Sun, Junhao Wang, Hongquan Liu, Kang Zhang, Chunyang Wang   +6 more
doaj   +1 more source

MCMC genome rearrangement [PDF]

Bioinformatics, 2003
Abstract Motivation: As more and more genomes have been sequenced, genomic data is rapidly accumulating. Genome-wide mutations are believed more neutral than local mutations such as substitutions, insertions and deletions, therefore phylogenetic investigations based on inversions, transpositions and inverted transpositions are less ...
openaire   +2 more sources

Core-genome scaffold comparison reveals the prevalence that inversion events are associated with pairs of inverted repeats

BMC Genomics, 2017
Background Genome rearrangement describes gross changes of chromosomal regions, plays an important role in evolutionary biology and has profound impacts on phenotype in organisms ranging from microbes to humans.
Dan Wang, Shuaicheng Li, Fei Guo, Kang Ning, Lusheng Wang   +4 more
doaj   +1 more source

Diploid-specific genome stability genes of S. cerevisiae: genomic screen reveals haploidization as an escape from persisting DNA rearrangement stress. [PDF]

, 2011
Maintaining a stable genome is one of the most important tasks of every living cell and the mechanisms ensuring it are similar in all of them. The events leading to changes in DNA sequence (mutations) in diploid cells occur one to two orders of magnitude
Skoneczna, Adrianna, Malgorzata Alabrudzinska, Marek Skoneczny, Alabrudzinska Malgorzata, Skoneczna Adrianna, Skoneczny Marek, Alabrudzinska, Malgorzata, Skoneczny, Marek, Adrianna Skoneczna   +8 more
core   +1 more source

Novel insights into chloroplast genome evolution in the green macroalgal genus Ulva (Ulvophyceae, Chlorophyta)

Frontiers in Plant Science, 2023
To understand the evolutionary driving forces of chloroplast (or plastid) genomes (plastomes) in the green macroalgal genus Ulva (Ulvophyceae, Chlorophyta), in this study, we sequenced and constructed seven complete chloroplast genomes from five Ulva ...
Feng Liu, Feng Liu, Feng Liu, Nansheng Chen, Nansheng Chen, Nansheng Chen, Hongshu Wang, Hongshu Wang, Hongshu Wang, Jiamin Li, Jiamin Li, Jiamin Li, Jing Wang, Jing Wang, Jing Wang, Fan Qu   +15 more
doaj   +1 more source

Ontology for genome comparison and genomic rearrangements

Comparative and Functional Genomics, 2004
AbstractWe present an ontology for describing genomes, genome comparisons, their evolution and biological function. This ontology will support the development of novel genome comparison algorithms and aid the community in discussing genomic evolution. It provides a framework for communication about comparative genomics, and a basis upon which further ...
Flanagan, K, Stevens, R, Pocock, M, Lee, P, Wipat, A   +4 more
openaire   +2 more sources

Recombination and population structure in salmonella enterica [PDF]

, 2011
Salmonella enterica is a bacterial pathogen that causes enteric fever and gastroenteritis in humans and animals. Although its population structure was long described as clonal, based on high linkage disequilibrium between loci typed by enzyme ...
Street, T, Bowden, R., Anjum, Muna F., Xavier Didelot, Falush Daniel, Donnelly Peter, Didelot, X., Anjum, MF, Donelly, P., McVean, G., Gil McVean, Vartul Sangal, Didelot, X, Bowden, Rory, Anjum Muna F., Donnelly, Peter, Anjum, Muna, Achtman, Mark, Sangal, V, Spencer, C., Falush, Daniel, Muna F. Anjum, Sangal, V., Tanya Golubchik, Anjum, M., Achtman, M., Daniel Falush, Peter Donnelly, McVean, G, Didelot, Xavier, Teresa Street, Mark Achtman, Bowden Rory, Spencer, Chris, Didelot Xavier, Sangal, Vartul, Street, T., Spencer Chris, McVean Gil, Spencer, C, Donelly, Peter, Chris Spencer, Donnelly, P, Street, Teresa, Street Teresa, Golubchik Tanya, Golubchik, T., Achtman Mark, Golubchik, Tanya, Falush, D, Rory Bowden, Bowden, R, McVean, Gilean, Sangal Vartul, McVean, Gil, Golubchik, T, Falush, D. ; https://orcid.org/, Muna F Anjum, Achtman, M   +58 more
core   +1 more source

Super short operations on both gene order and intergenic sizes

Algorithms for Molecular Biology, 2019
Background The evolutionary distance between two genomes can be estimated by computing a minimum length sequence of operations, called genome rearrangements, that transform one genome into another.
Andre R. Oliveira, Géraldine Jean, Guillaume Fertin, Ulisses Dias, Zanoni Dias   +4 more
doaj   +1 more source