Results 11 to 20 of about 81,508 (252)

Rearrangement Events on Circular Genomes

open access: yesBulletin of Mathematical Biology, 2023
AbstractEarly literature on genome rearrangement modelling views the problem of computing evolutionary distances as an inherently combinatorial one. In particular, attention is given to estimating distances using the minimum number of events required to transform one genome into another.
Joshua Stevenson   +2 more
openaire   +4 more sources

Finding local genome rearrangements [PDF]

open access: yesAlgorithms for Molecular Biology, 2018
The double cut and join (DCJ) model of genome rearrangement is well studied due to its mathematical simplicity and power to account for the many events that transform gene order. These studies have mostly been devoted to the understanding of minimum length scenarios transforming one genome into another. In this paper we search instead for rearrangement
Swenson, Krister, Simonaitis, Pijus
openaire   +6 more sources

Comparative genomics reveals insight into the evolutionary origin of massively scrambled genomes

open access: yeseLife, 2022
Ciliates are microbial eukaryotes that undergo extensive programmed genome rearrangement, a natural genome editing process that converts long germline chromosomes into smaller gene-rich somatic chromosomes.
Yi Feng   +6 more
doaj   +1 more source

Rearrangement of Noisy Genomes [PDF]

open access: yes, 2006
Measures of distance between genomic maps are inflated by high levels of noise due to incorrectly resolved paralogy and error at the mapping, sequencing and alignment levels. Comparison is also hampered by lack of information on gene orientation and lack gene order.
Chunfang Zheng, David Sankoff
openaire   +1 more source

progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement. [PDF]

open access: yesPLoS ONE, 2010
Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms.We describe a new method to ...
Aaron E Darling, Bob Mau, Nicole T Perna
doaj   +1 more source

Linkage Disequilibrium-Based Inference of Genome Homology and Chromosomal Rearrangements Between Species

open access: yesG3: Genes, Genomes, Genetics, 2020
The aim of this study was to analyze the genomic homology between cattle (Bos taurus) and buffaloes (Bubalus bubalis) and to propose a rearrangement of the buffalo genome through linkage disequilibrium analyses of buffalo SNP markers referenced in the ...
Daniel Jordan de Abreu Santos   +9 more
doaj   +1 more source

A New Algorithm for Identifying Genome Rearrangements in the Mammalian Evolution

open access: yesFrontiers in Genetics, 2019
Genome rearrangements are the evolutionary events on level of genomes. It is a global view on evolution research of species to analyze the genome rearrangements.
Juan Wang   +4 more
doaj   +1 more source

Combinatorics of Genome Rearrangements [PDF]

open access: yes, 2009
A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar.
Fertin, Guillaume   +4 more
openaire   +3 more sources

Genome dedoubling by DCJ and reversal

open access: yesBMC Bioinformatics, 2011
Background Segmental duplications in genomes have been studied for many years. Recently, several studies have highlighted a biological phenomenon called breakpoint-duplication that apparently associates a significant proportion of segmental duplications ...
Ouangraoua Aïda   +2 more
doaj   +1 more source

Sorting Permutations by λ-Operations [PDF]

open access: yesJournal of Universal Computer Science, 2019
For estimating the evolutionary distance between genomes of two different organisms, many sorting permutation problems have emerged. A well accepted way to do this is considering the smallest sequence of rearrangement events { mutations which affect ...
Guilherme Henrique Santos Miranda   +2 more
doaj   +3 more sources

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