Results 21 to 30 of about 81,508 (252)
Genome rearrangements with duplications [PDF]
BMC Bioinformatics, 2010 Finding sequences of evolutionary operations that transform one genome into another is a classical problem in comparative genomics. While most of the genome rearrangement algorithms assume that there is exactly one copy of each gene in both genomes, this does not reflect the biological reality very well - most of the studied genomes contain duplicated ...
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Programmed genome rearrangements in ciliates [PDF]
Cellular and Molecular Life Sciences, 2020 AbstractCiliates are a highly divergent group of unicellular eukaryotes with separate somatic and germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly linked to extremely laborious developmentally regulated genome rearrangements in the development of a new somatic genome/nuclei following sex.
Iwona Rzeszutek +2 more
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Cell Reports, 2017 RNAi-mediated positive feedback loops are pivotal for the maintenance of heterochromatin, but how they are downregulated at heterochromatin-euchromatin borders is not well understood.
Jan H. Suhren +5 more
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eLife, 2020 Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a Saccharomyces cerevisiae genetic system that generates gross chromosomal rearrangements (GCRs) mediated by foldback ...
Bin-zhong Li +2 more
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Repeats of Unusual Size in Plant Mitochondrial Genomes: Identification, Incidence and Evolution
G3: Genes, Genomes, Genetics, 2019 Plant mitochondrial genomes have excessive size relative to coding capacity, a low mutation rate in genes and a high rearrangement rate. They also have abundant non-tandem repeats often including pairs of large repeats which cause isomerization of the ...
Emily L. Wynn, Alan C. Christensen
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Nature Communications, 2020 Heat stress can activate heterochromatin-associated transposon elements (TEs). Here, the authors show that heat stress leads to global rearrangement of 3D genome and TEs activation closely correlates with 3D chromatin organization rearrangement in ...
Linhua Sun +8 more
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MCMC genome rearrangement [PDF]
Bioinformatics, 2003 Abstract Motivation: As more and more genomes have been sequenced, genomic data is rapidly accumulating. Genome-wide mutations are believed more neutral than local mutations such as substitutions, insertions and deletions, therefore phylogenetic investigations based on inversions, transpositions and inverted transpositions are less ...
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BMC Genomics, 2017 Background Genome rearrangement describes gross changes of chromosomal regions, plays an important role in evolutionary biology and has profound impacts on phenotype in organisms ranging from microbes to humans.
Dan Wang +4 more
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An intelligent recognition method of chromosome rearrangement patterns based on information entropy
Scientific Reports, 2022 Chromosome rearrangements play an important role in the speciation of plants and animals, and the recognition of chromosome rearrangement patterns is helpful to elucidate the mechanism of species differentiation at the chromosome level.
Fushun Wang +6 more
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Dynamics of genome rearrangement in bacterial populations.
PLoS Genetics, 2008 Genome structure variation has profound impacts on phenotype in organisms ranging from microbes to humans, yet little is known about how natural selection acts on genome arrangement.
Aaron E Darling +2 more
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