Results 71 to 80 of about 85,734 (198)
A model for rearrangements in RNA genomes
Nucleic Acids Research, 1995 Engineered mutants of Theiler's murine encephalomyelitis virus (TMEV) and poliovirus having altered spacing between the oligopyrimidine and AUG moieties of a translational control element are known to generate pseudorevertants with deletions or insertions that tend to restore the wild-type structure of this element.
E V, Pilipenko, A P, Gmyl, V I, Agol
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Large genomic rearrangements in MECP2 [PDF]
Human Mutation, 2005 In 1999, mutations in the X-linked gene methyl-CpG-binding protein 2 (MECP2) were first reported in patients with Rett syndrome (RTT). The MECP2 gene is located at Xq28 and consists of 4 exons. About 80-90 % of the classic RTT patients harbor mutations in the coding region of MECP2, while the molecular cause is unknown in the remaining 10-20%.
Kirstine, Ravn +5 more
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BMC Genomics, 2010 Background Bacterial phenotype may be profoundly affected by the physical arrangement of their genes in the genome. The Gram-negative species Aggregatibacter actinomycetemcomitans is a major etiologic agent of human periodontitis. Individual clonal types
Kittichotirat Weerayuth +2 more
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Royal Society Open ScienceInsects harbour diverse maternally inherited bacteria and viruses, some of which have evolved to kill the male progeny of their hosts (male killing: MK). The fly species Drosophila biauraria carries a maternally transmitted MK-inducing partiti-like virus,
Hiroshi Arai +2 more
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, 2019 Whole-genome sequencing using massively parallel sequencing technologies enables accurate detection of somatic rearrangements in cancer. Pinpointing large numbers of rearrangement breakpoints to base-pair resolution allows analysis of rearrangement ...
Meyerson, Matthew +8 more
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BMC Biology, 2022 Background A single circular mitochondrial (mt) genome is a common feature across most metazoans. The mt-genome includes protein-coding genes involved in oxidative phosphorylation, as well as RNAs necessary for translation of mt-RNAs, whose order and ...
Shiqian Feng +7 more
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Genome rearrangement with gene families [PDF]
Bioinformatics, 1999 Abstract Motivation: The theory and practice of genome rearrangement analysis breaks down in the biologically widespread contexts where each gene may be present in a number of copies, not necessarily contiguous. In some of these contexts it is, however, appropriate to ask which members of each gene family in two genomes G and H, lengths ...
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DCJ-RNA - double cut and join for RNA secondary structures
BMC Bioinformatics, 2017 Background Genome rearrangements are essential processes for evolution and are responsible for existing varieties of genome architectures. Many studies have been conducted to obtain an algorithm that identifies the minimum number of inversions that are ...
Ghada H. Badr, Haifa A. Al-aqel
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Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability [PDF]
, 2012 Whole-genome sequencing using massively parallel sequencing technologies enables accurate detection of somatic rearrangements in cancer. Pinpointing large numbers of rearrangement breakpoints to base-pair resolution allows analysis of rearrangement ...
Lander, Eric Steven +8 more
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BMC Genomics, 2006 Background Because amphibians arise from a branch of the vertebrate evolutionary tree that is juxtaposed between fishes and amniotes, they provide important comparative perspective for reconstructing character changes that have occurred during vertebrate
Voss S Randal, Smith Jeramiah J
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