Results 121 to 130 of about 5,201,388 (369)

Genome sequence and analysis of the tuber crop potato

Nature, 2011
Potato (Solanum tuberosum L.) is the world’s most important non-grain food crop and is central to global food security. It is clonally propagated, highly heterozygous, autotetraploid, and suffers acute inbreeding depression.
Xun Xu, S. Pan, Shifeng Cheng, Bo Zhang, Desheng Mu, Peixiang Ni, Gengyun Zhang, Shuang Yang, Ruiqiang Li, Jun Wang, G. Orjeda, Frank Guzman, M. Torres, R. Lozano, Olga Ponce, D. Martínez, Germán De la Cruz, S. Chakrabarti, V. U. Patil, K. Skryabin, B. Kuznetsov, N. Ravin, T. Kolganova, A. Beletsky, A. V. Mardanov, A. Di Genova, D. Bolser, David M. A. Martin, Guangcun Li, Yu Yang, H. Kuang, Qun Hu, Xingyao Xiong, G. Bishop, B. Sagredo, N. Mejía, W. Zagórski, R. Gromadka, J. Gawor, Paweł Szczęsny, Sanwen Huang, Zhonghua Zhang, Chunbo Liang, Jun He, Ying Li, Ying He, Jianfei Xu, Youjun Zhang, Binyan Xie, Yong-chen Du, D. Qu, M. Bonierbale, M. Ghislain, M. D. R. Herrera, G. Giuliano, M. Pietrella, G. Perrotta, Paolo Facella, Kimberly O'Brien, S. Feingold, Leandro E Barreiro, G. Massa, Luis Diambra, Brett Whitty, Brieanne Vaillancourt, Haining Lin, A. Massa, M. Geoffroy, Steven Lundback, D. DellaPenna, C. R. Buell, S. Sharma, D. Marshall, R. Waugh, G. Bryan, M. Destefanis, I. Nagy, D. Milbourne, Susan J. Thomson, M. Fiers, J. Jacobs, K. Nielsen, Mads Sønderkær, M. Iovene, G. A. Torres, Jiming Jiang, R. Veilleux, C. Bachem, Jan M. de Boer, T. Borm, B. Kloosterman, H. V. van Eck, E. Datema, B. T. Hekkert, A. Goverse, R. V. Van Ham, R. Visser   +96 more
semanticscholar   +1 more source

Genome sequencing and cancer [PDF]

Current Opinion in Genetics & Development, 2012
New technologies for DNA sequencing, coupled with advanced analytical approaches, are now providing unprecedented speed and precision in decoding human genomes. This combination of technology and analysis, when applied to the study of cancer genomes, is revealing specific and novel information about the fundamental genetic mechanisms that underlie ...
openaire   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Complete genome sequence of Borrelia afzelii K78 and comparative genome analysis.

PLoS ONE, 2015
The main Borrelia species causing Lyme borreliosis in Europe and Asia are Borrelia afzelii, B. garinii, B. burgdorferi and B. bavariensis. This is in contrast to the United States, where infections are exclusively caused by B. burgdorferi.
Wolfgang Schüler, Ignas Bunikis, Jacqueline Weber-Lehman, Pär Comstedt, Sabrina Kutschan-Bunikis, Gerold Stanek, Jutta Huber, Andreas Meinke, Sven Bergström, Urban Lundberg   +9 more
doaj   +1 more source

A Hybrid Approach for de novo Human Genome Sequence Assembly and Phasing

Nature Methods, 2016
Despite tremendous progress in genome sequencing, the basic goal of producing a phased (haplotype-resolved) genome sequence with end-to-end contiguity for each chromosome at reasonable cost and effort is still unrealized.
Y. Mostovoy, Michal Levy-Sakin, Jessica C Lam, E. Lam, A. Hastie, Patrick J. Marks, Joyce Lee, Catherine J. Chu, C. Lin, Ž. Džakula, H. Cao, S. A. Schlebusch, Kristina M. Giorda, Michael Schnall-Levin, J. Wall, P. Kwok   +15 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

The Norway spruce genome sequence and conifer genome evolution

Nature, 2013
Conifers have dominated forests for more than 200 million years and are of huge ecological and economic importance. Here we present the draft assembly of the 20-gigabase genome of Norway spruce (Picea abies), the first available for any gymnosperm.
Björn Nystedt, N. Street, Anna Wetterbom, A. Zuccolo, Yao-cheng Lin, Douglas G. Scofield, F. Vezzi, Nicolas Delhomme, Stefania Giacomello, A. Alexeyenko, Riccardo Vicedomini, Kristoffer Sahlin, Ellen Sherwood, M. Elfstrand, Lydia Gramzow, Kristina Holmberg, J. Hällman, O. Keech, Lisa Klasson, M. Koriabine, Melis Kucukoglu, M. Käller, J. Luthman, Fredrik Lysholm, Totte Niittylä, Å. Olson, Nemanja Rilakovic, C. Ritland, J. Rosselló, J. Sena, T. Svensson, Carlos Talavera-López, G. Theißen, H. Tuominen, K. Vanneste, Zhide Wu, Bo Zhang, P. Zerbe, Lars Arvestad, R. Bhalerao, J. Bohlmann, J. Bousquet, R. Gil, T. R. Hvidsten, P. Jong, J. MacKay, M. Morgante, K. Ritland, B. Sundberg, S. L. Thompson, Y. Peer, B. Andersson, O. Nilsson, P. Ingvarsson, J. Lundeberg, S. Jansson   +55 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Complete Genome Sequence of Pseudoxanthomonas taiwanensis AL17 and its Potential Genes

Journal of Pure and Applied Microbiology
Several reports on genome sequencing using Next Generation Sequencing (NGS) to identify the total genome were extensively carried out; however, genome identification on thermophilic microorganisms is still limited.
Deviyanthi Nur Afifah, Leyla Novita Brigiyanti, Made Puspasari Widhiastuty, Elvi Restiawaty, Akhmaloka   +4 more
doaj   +1 more source

Genome sequencing and annotation of Proteus sp. SAS71

Genomics Data, 2015
We report draft genome sequence of Proteus sp. strain SAS71, isolated from water spring in Aljouf region, Saudi Arabia. The draft genome size is 3,037,704 bp with a G + C content of 39.3% and contains 6 rRNA sequence (single copies of 5S, 16S & 23S rRNA).
Samy Selim, Sherif Hassan, Nashwa Hagagy
doaj   +1 more source