Results 131 to 140 of about 5,337,258 (380)

Genome sequencing and annotation of Proteus sp. SAS71

Genomics Data, 2015
We report draft genome sequence of Proteus sp. strain SAS71, isolated from water spring in Aljouf region, Saudi Arabia. The draft genome size is 3,037,704 bp with a G + C content of 39.3% and contains 6 rRNA sequence (single copies of 5S, 16S & 23S rRNA).
Samy Selim, Sherif Hassan, Nashwa Hagagy
doaj   +1 more source

Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement

PLoS ONE, 2014
Advances in modern sequencing technologies allow us to generate sufficient data to analyze hundreds of bacterial genomes from a single machine in a single day.
B. J. Walker, T. Abeel, Terrance Shea, M. Priest, Amr Abouelliel, Sharadha Sakthikumar, Christina A. Cuomo, Qiandong Zeng, J. Wortman, Sarah K. Young, A. Earl   +10 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Characteristics of the a sequence of the duck Plague virus genome and specific cleavage of the viral genome based on the a sequence

Veterinary Research
During the replication process, the herpesvirus genome forms the head-to-tail linked concatemeric genome, which is then cleaved and packaged into the capsid.
Qiao Yang, Yaya Feng, Yuanxin Zhang, Mingshu Wang, Renyong Jia, Dekang Zhu, Shun Chen, Mafeng Liu, Xinxin Zhao, Ying Wu, Shaqiu Zhang, Bin Tian, Xumin Ou, Sai Mao, Juan Huang, Qun Gao, Di Sun, Zhen Wu, Yu He, Ling Zhang, Yanling Yu, Anchun Cheng   +21 more
doaj   +1 more source

Complete genome sequence of Borrelia afzelii K78 and comparative genome analysis.

PLoS ONE, 2015
The main Borrelia species causing Lyme borreliosis in Europe and Asia are Borrelia afzelii, B. garinii, B. burgdorferi and B. bavariensis. This is in contrast to the United States, where infections are exclusively caused by B. burgdorferi.
Wolfgang Schüler, Ignas Bunikis, Jacqueline Weber-Lehman, Pär Comstedt, Sabrina Kutschan-Bunikis, Gerold Stanek, Jutta Huber, Andreas Meinke, Sven Bergström, Urban Lundberg   +9 more
doaj   +1 more source

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita [PDF]

, 2008
Pierre Abad, Jérôme Gouzy, Jean‐Marc Aury, Philippe Castagnone‐Sereno, Étienne Danchin, Emeline Deleury, Laetitia Perfus‐Barbeoch, Véronique Anthouard, François Artiguenave, Vivian Blok, Marie‐Cécile Caillaud, Pedro M. Coutinho, Corinne Da Silva, Francesca De Luca, Florence Deau, Magali Esquibet, Timothée Flutre, Jared V. Goldstone, Noureddine Hamamouch, Tarek Hewezi, Olivier Jaillon, Claire Jubin, Paola Leonetti, Marc Magliano, Tom Maier, Gabriel V. Markov, Paul McVeigh, Graziano Pesole, Julie Poulain, Marc Robinson‐Rechavi, Erika Sallet, Béatrice Segurens, Delphine Steinbach, Tom Tytgat, Edgardo Ugarte, Cyril Van Ghelder, Pasqua Veronico, Thomas J. Baum, Mark Blaxter, T. Bleve‐Zacheo, Eric Davis, Jonathan J. Ewbank, Bruno Favery, Éric Grenier, Bernard Henrissat, John T. Jones, Vincent Laudet, Aaron G. Maule, Hadi Quesneville, Marie-Noëlle Rosso, Thomas Schiex, Geert Smant, Jean Weissenbach, Patrick Wincker   +53 more
openalex   +1 more source

SyRI: finding genomic rearrangements and local sequence differences from whole-genome assemblies

Genome Biology, 2019
Genomic differences range from single nucleotide differences to complex structural variations. Current methods typically annotate sequence differences ranging from SNPs to large indels accurately but do not unravel the full complexity of structural ...
M. Goel, Hequan Sun, Wen-Biao Jiao, Korbinian Schneeberger   +3 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The Norway spruce genome sequence and conifer genome evolution

Nature, 2013
Conifers have dominated forests for more than 200 million years and are of huge ecological and economic importance. Here we present the draft assembly of the 20-gigabase genome of Norway spruce (Picea abies), the first available for any gymnosperm.
Björn Nystedt, N. Street, Anna Wetterbom, A. Zuccolo, Yao-cheng Lin, Douglas G. Scofield, F. Vezzi, Nicolas Delhomme, Stefania Giacomello, A. Alexeyenko, Riccardo Vicedomini, Kristoffer Sahlin, Ellen Sherwood, M. Elfstrand, Lydia Gramzow, Kristina Holmberg, J. Hällman, O. Keech, Lisa Klasson, M. Koriabine, Melis Kucukoglu, M. Käller, J. Luthman, Fredrik Lysholm, Totte Niittylä, Å. Olson, Nemanja Rilakovic, C. Ritland, J. Rosselló, J. Sena, T. Svensson, Carlos Talavera-López, G. Theißen, H. Tuominen, K. Vanneste, Zhide Wu, Bo Zhang, P. Zerbe, Lars Arvestad, R. Bhalerao, J. Bohlmann, J. Bousquet, R. Gil, T. R. Hvidsten, P. Jong, J. MacKay, M. Morgante, K. Ritland, B. Sundberg, S. L. Thompson, Y. Peer, B. Andersson, O. Nilsson, P. Ingvarsson, J. Lundeberg, S. Jansson   +55 more
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source