Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Chloroplast genome sequence of Solanum demissum, a wild tuber-bearing species was completed
Solanum demissum is a wild tuber-bearing species belonging to Solanaceae family. The complete chloroplast genome of S. demissum was constituted by de novo assembly using a small amount of whole genome sequencing data.
Kwang-Soo Cho+3 more
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
The complete chloroplast genome of Solanum berthaultii, one of the potato wild relative species
Solanum berthaultii is a wild species belonging to Solanaceae family. The complete chloroplast genome of S. berthaultii was constituted by de novo assembly using a small amount of whole genome sequencing data. The chloroplast genome of S. berthaultii was
Tae-Ho Park
doaj +1 more source
A Gapless, Unambiguous Genome Sequence of the Enterohemorrhagic Escherichia coli O157:H7 Strain EDL933. [PDF]
Escherichia coli EDL933 is the prototypic strain for enterohemorrhagic E. coli serotype O157:H7, associated with deadly food-borne outbreaks. Because the publicly available sequence of the EDL933 genome has gaps and >6,000 ambiguous base calls, we ...
Aziz, Ramy K+4 more
core +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Chloroplast genome sequence of the wild tetraploid potato relative Solanum stoloniferum
Solanum stoloniferum is a wild tuber-bearing species belonging to Solanaceae family. The complete chloroplast genome of S. stoloniferum was constituted by de novo assembly using a small amount of whole genome sequencing data. The chloroplast genome of S.
Tae-Ho Park
doaj +1 more source
A new and improved genome sequence of Cannabis sativa
Cannabis is a diploid species (2n = 20), the estimated haploid genome sizes of the female and male plants using flow cytometry are 818 and 843 Mb respectively.
Shivraj Braich +3 more
doaj +1 more source
Evaluation of genome sequencing quality in selected plant species using expressed sequence tags. [PDF]
BACKGROUND: With the completion of genome sequencing projects for more than 30 plant species, large volumes of genome sequences have been produced and stored in online databases.
Lingfei Shangguan+7 more
doaj +1 more source
Genome sequence of Christensenella minuta DSM 22607T [PDF]
Obesity influences and is influenced by the human gut microbiome. Here, we present the genome of Christensenella minuta, a highly heritable bacterial species which has been found to be strongly associated with obesity through an unknown biological ...
Hallsworth-Pepin, Kymberlie+4 more
core +2 more sources