Results 71 to 80 of about 4,549,742 (256)

Whole genome sequencing in pharmacogenomics [PDF]

Frontiers in Pharmacology, 2015
Pharmacogenomics aims to shed light on the role of genes and genomic variants in clinical treatment response. Although, several drug-gene relationships are characterized to date, many challenges still remain toward the application of pharmacogenomics in the clinic; clinical guidelines for pharmacogenomic testing are still in their infancy, whereas the ...
Theodora Katsila, George P. Patrinos
openaire   +4 more sources

Simple Sequence Repeat Marker Development and Mapping Targeted to Previously Unmapped Regions of the Strawberry Genome Sequence

The Plant Genome, 2011
The genome sequence of the woodland strawberry ( L.) is an important resource providing a reference for comparative genomics studies and future sequenced rosaceous species and has great utility as a model for the development of markers for mapping in the
Daniel J. Sargent, Paulina Kuchta, Elena Lopez Girona, Hailong Zhang, Thomas M. Davis, Jean-Marc Celton, Annalisa Marchese, Malgorzata Korbin, Kevin M. Folta, Vladimir Shulaev, David W. Simpson   +10 more
doaj   +1 more source

Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution

Nature Biotechnology, 2015
Gossypium hirsutum has proven difficult to sequence owing to its complex allotetraploid (AtDt) genome. Here we produce a draft genome using 181-fold paired-end sequences assisted by fivefold BAC-to-BAC sequences and a high-resolution genetic map.
Fuguang Li, Guangyi Fan, Cai-rui Lu, G. Xiao, Changsong Zou, R. Kohel, Zhiying Ma, Haihong Shang, Xiongfeng Ma, Jianyong Wu, Xinming Liang, Gai Huang, R. Percy, Kun Liu, Weihua Yang, Wenbin Chen, X. Du, Chengcheng Shi, You-lu Yuan, W. Ye, Xin Liu, Xueyang Zhang, Weiqing Liu, Hengling Wei, Shoujun Wei, Guodong Huang, Xianlong Zhang, Shuijin Zhu, He Zhang, F. Sun, Xingfen Wang, Jie Liang, Jiahao Wang, Qiang He, Leihuan Huang, Jun Wang, Jinjie Cui, G. Song, Kunbo Wang, Xun Xu, John Z. Yu, Yuxian Zhu, Shuxun Yu   +42 more
semanticscholar   +1 more source

Genome-wide sequence variations between wild and cultivated tomato species revisited by whole genome sequence mapping

BMC Genomics, 2017
Background Cultivated tomato (Solanum lycopersicum L.) is the second most important vegetable crop after potato and a member of thirteen interfertile species of Solanum genus.
Kamlesh Kumar Sahu, Debasis Chattopadhyay   +1 more
doaj   +1 more source

The channel catfish genome sequence provides insights into the evolution of scale formation in teleosts

Nature Communications, 2016
Catfish represent 12% of teleost or 6.3% of all vertebrate species, and are of enormous economic value. Here we report a high-quality reference genome sequence of channel catfish (Ictalurus punctatus), the major aquaculture species in the US.
Zhanjiang Liu, Shikai Liu, Jun Yao, Lisui Bao, Jiaren Zhang, Yun Li, Chen Jiang, Luyang Sun, Ruijia Wang, Yu Zhang, Tao Zhou, Qifan Zeng, Qiang Fu, Sen Gao, Ning Li, S. Koren, Yanliang Jiang, A. Zimin, Peng Xu, A. Phillippy, Xin Geng, Lin Song, Fanyue Sun, Chao Li, Xiaozhu Wang, Ailu Chen, Yulin Jin, Zihao Yuan, Yujia Yang, Suxu Tan, E. Peatman, Jianguo Lu, Zhenkui Qin, R. Dunham, Zhaoxia Li, T. Sonstegard, Jianbin Feng, R. Danzmann, Steven G. Schroeder, B. Scheffler, M. Duke, Linda Ballard, H. Kucuktas, L. Kaltenboeck, Haixia Liu, J. Armbruster, Yangjie Xie, M. L. Kirby, Yiying Tian, M. Flanagan, W. Mu, G. Waldbieser   +51 more
semanticscholar   +1 more source

Genome sequencing and annotation of Stenotrophomonas sp. SAM8

Genomics Data, 2015
We report draft genome sequence of Stenotrophomonas sp. strain SAM8, isolated from environmental water. The draft genome size is 3,665,538 bp with a G + C content of 67.2% and contains 6 rRNA sequence (single copies of 5S, 16S & 23S rRNA).
Samy Selim, Sherif Hassan, Nashwa Hagagy
doaj   +1 more source

Genome sequencing and cancer [PDF]

Current Opinion in Genetics & Development, 2012
New technologies for DNA sequencing, coupled with advanced analytical approaches, are now providing unprecedented speed and precision in decoding human genomes. This combination of technology and analysis, when applied to the study of cancer genomes, is revealing specific and novel information about the fundamental genetic mechanisms that underlie ...
openaire   +3 more sources

Deletion of all Cochliobolus heterostrophus Monofunctional Catalase-Encoding Genes Reveals a Role for One in Sensitivity to Oxidative Stress but None with a Role in Virulence

Molecular Plant-Microbe Interactions, 2003
The genome of the maize pathogen Cochliobolus heterostrophus encodes three unlinked monofunctional catalase-encoding (CAT) genes that singly or in combination could offer protection against the harmful effects of oxidative stress.
Barbara Robbertse, O. C. Yoder, Anita Nguyen, Conrad L. Schoch, B. Gillian Turgeon   +4 more
doaj   +1 more source

Complete Genome Sequence of Pseudoxanthomonas taiwanensis AL17 and its Potential Genes

Journal of Pure and Applied Microbiology
Several reports on genome sequencing using Next Generation Sequencing (NGS) to identify the total genome were extensively carried out; however, genome identification on thermophilic microorganisms is still limited.
Deviyanthi Nur Afifah, Leyla Novita Brigiyanti, Made Puspasari Widhiastuty, Elvi Restiawaty, Akhmaloka   +4 more
doaj   +1 more source

Genome-wide SNP identification by high-throughput sequencing and selective mapping allows sequence assembly positioning using a framework genetic linkage map

BMC Biology, 2010
Background Determining the position and order of contigs and scaffolds from a genome assembly within an organism's genome remains a technical challenge in a majority of sequencing projects. In order to exploit contemporary technologies for DNA sequencing,
Xu Xiangming, Sargent Daniel J, Christoffels Alan, Celton Jean-Marc, Rees D Jasper G   +4 more
doaj   +1 more source