Results 71 to 80 of about 1,799,072 (348)

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

The Genome Sequence DataBase [PDF]

open access: yesNucleic Acids Research, 2000
The Genome Sequence DataBase (GSDB) is a database of publicly available nucleotide sequences and their associated biological and bibliographic information. Several notable changes have occurred in the past year: GSDB stopped accepting data submissions from researchers; ownership of data submitted to GSDB was transferred to GenBank; sequence analysis ...
M. P. Skupski   +8 more
openaire   +3 more sources

Chloroplast genome sequence of Solanum demissum, a wild tuber-bearing species was completed

open access: yesMitochondrial DNA. Part B. Resources, 2019
Solanum demissum is a wild tuber-bearing species belonging to Solanaceae family. The complete chloroplast genome of S. demissum was constituted by de novo assembly using a small amount of whole genome sequencing data.
Kwang-Soo Cho   +3 more
doaj   +1 more source

Whole Genome Mapping with Feature Sets from High-Throughput Sequencing Data. [PDF]

open access: yesPLoS ONE, 2016
A good physical map is essential to guide sequence assembly in de novo whole genome sequencing, especially when sequences are produced by high-throughput sequencing such as next-generation-sequencing (NGS) technology.
Yonglong Pan   +4 more
doaj   +1 more source

The CACTA transposon Bot1 played a major role in Brassica genome divergence and gene proliferation [PDF]

open access: yes, 2008
We isolated and characterized a Brassica C genome-specific CACTA element, which was designated Bot1 (Brassica oleracea transposon 1). After analysing phylogenetic relationships, copy numbers and sequence similarity of Bot1 and Bot1 analogues in B ...
AGI, Arabidopsis Genome Initiative   +80 more
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The Coffee Genome Hub : [W185] [PDF]

open access: yes, 2014
The whole genome sequence of Coffea canephora, the perennial diploid species known as Robusta, has been recently obtained and portends to be published and released in the coming months.
Bocs, Stéphanie   +7 more
core  

A time series model of CDS sequences in complete genome [PDF]

open access: yes, 2000
A time series model of CDS sequences in complete genome is proposed. A map of DNA sequence to integer sequence is given. The correlation dimensions and Hurst exponents of CDS sequences in complete genome of bacteria are calculated. Using the average of
Wang, Bin, Yu, Zu-Guo
core   +2 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Genome-Tools: A Flexible Package for Genome Sequence Analysis

open access: yesBioTechniques, 2002
Genome-tools is a Perl module, a set of programs, and a user interface that facilitates access to genome sequence information. The package is flexible, extensible, and designed to be accessible and useful to both nonprogrammers and programmers.
William Lee, Swaine L. Chen
doaj   +1 more source

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