Results 81 to 90 of about 5,201,388 (369)

Genome-Tools: A Flexible Package for Genome Sequence Analysis

BioTechniques, 2002
Genome-tools is a Perl module, a set of programs, and a user interface that facilitates access to genome sequence information. The package is flexible, extensible, and designed to be accessible and useful to both nonprogrammers and programmers.
William Lee, Swaine L. Chen
doaj   +1 more source

Whole Genome Mapping with Feature Sets from High-Throughput Sequencing Data. [PDF]

PLoS ONE, 2016
A good physical map is essential to guide sequence assembly in de novo whole genome sequencing, especially when sequences are produced by high-throughput sequencing such as next-generation-sequencing (NGS) technology.
Yonglong Pan, Xiaoming Wang, Lin Liu, Hao Wang, Meizhong Luo   +4 more
doaj   +1 more source

In silico Gene Characterization and biological annotation of Aspergillus niger CBS 513.88 [PDF]

, 2011
Genome annotation is the process of estimation of biological features from genomic data. The target of a genome annotation is to identify the key features of the genome sequence particularly, the genes and gene products.
Anuraj Nayarisseri, Anuraj Nayarisseri, Mayura Maynal, Mukesh Yadav, Rajesh Patidar, Vini Lokhande   +5 more
core   +2 more sources

Linking the International Wheat Genome Sequencing Consortium bread wheat reference genome sequence to wheat genetic and phenomic data

Genome Biology, 2018
The Wheat@URGI portal has been developed to provide the international community of researchers and breeders with access to the bread wheat reference genome sequence produced by the International Wheat Genome Sequencing Consortium. Genome browsers, BLAST,
M. Alaux, J. Rogers, T. Letellier, Raphael Flores, Françoise Alfama, C. Pommier, N. Mohellibi, Sophie Durand, Erik Kimmel, Célia Michotey, Claire Guerche, M. Loaec, Mathilde Lainé, Delphine Steinbach, F. Choulet, Hélène Rimbert, P. Leroy, N. Guilhot, J. Salse, C. Feuillet, E. Paux, K. Eversole, A. Adam-Blondon, H. Quesneville   +23 more
semanticscholar   +1 more source

The Genome Sequence DataBase [PDF]

Nucleic Acids Research, 2000
The Genome Sequence DataBase (GSDB) is a database of publicly available nucleotide sequences and their associated biological and bibliographic information. Several notable changes have occurred in the past year: GSDB stopped accepting data submissions from researchers; ownership of data submitted to GSDB was transferred to GenBank; sequence analysis ...
M. P. Skupski, Carol Harger, Wen Huang, Andrew Farmer, Jeff T. Inman, Jennifer W. Weller, Faye D. Schilkey, Donald Kiphart, Guanghong Chen   +8 more
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

The complete genome sequence of a Neandertal from the Altai Mountains

Nature, 2013
We present a high-quality genome sequence of a Neanderthal woman from Siberia. We show that her parents were related at the level of half-siblings and that mating among close relatives was common among her recent ancestors.
Kay Prüfer, F. Racimo, N. Patterson, F. Jay, S. Sankararaman, S. Sawyer, Anja Heinze, Gabriel Renaud, Peter H. Sudmant, C. D. Filippo, Heng Li, Swapan Mallick, M. Dannemann, Qiaomei Fu, Martin Kircher, Martin Kuhlwilm, M. Lachmann, M. Meyer, M. Ongyerth, Michael F. Siebauer, Christoph Theunert, Arti Tandon, Priya Moorjani, Joseph K. Pickrell, J. Mullikin, Samuel H. Vohr, R. Green, Ines Hellmann, Philip L. F. Johnson, H. Blanché, H. Cann, J. Kitzman, J. Shendure, E. Eichler, E. Lein, Trygve E Bakken, L. Golovanova, V. Doronichev, M. Shunkov, A. Derevianko, B. Viola, M. Slatkin, D. Reich, J. Kelso, S. Pääbo   +44 more
semanticscholar   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Complete genome sequence of Kribbella flavida type strain (IFO 14399). [PDF]

, 2010
The genus Kribbella consists of 15 species, with Kribbella flavida (Park et al. 1999) as the type species. The name Kribbella was formed from the acronym of the Korea Research Institute of Bioscience and Biotechnology, KRIBB.
Brettin, Thomas, Bristow, Jim, Bruce, David, Chain, Patrick, Chang, Yun-Juan, Chen, Amy, Chen, Feng, Cheng, Jan-Fang, Copeland, Alex, Eisen, Jonathan A, Glavina Del Rio, Tijana, Goodwin, Lynne, Göker, Markus, Hauser, Loren, Hugenholtz, Philip, Ivanova, Natalia, Jeffries, Cynthia D, Klenk, Hans-Peter, Kyrpides, Nikos C, Labutti, Kurt, Land, Miriam, Lapidus, Alla, Lucas, Susan, Markowitz, Victor, Mavromatis, Konstantinos, Mikhailova, Natalia, Nolan, Matt, Palaniappan, Krishna, Pati, Amrita, Pitluck, Sam, Pukall, Rüdiger, Rohde, Manfred, Tice, Hope   +32 more
core   +1 more source

ntEdit: scalable genome sequence polishing

bioRxiv, 2019
In the modern genomics era, genome sequence assemblies are routine practice. However, depending on the methodology, resulting drafts may contain considerable base errors.
R. Warren, Lauren Coombe, H. Mohamadi, Jessica Zhang, B. Jaquish, N. Isabel, Steven J. M. Jones, J. Bousquet, J. Bohlmann, I. Birol   +9 more
semanticscholar   +1 more source