Results 251 to 260 of about 2,337,583 (311)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Whole-genome sequencing of adenovirus 41 directly from wastewater using nested overlapping PCR and MinION. [PDF]

Microbiol Spectr
Nusrat N, Meschke JS, Swanstrom R, Rodríguez RA.   +3 more
europepmc   +1 more source

Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

, 2004
CHIAROMONTE, FRANCESCA, International Chicken Genome Sequencing Consortium including, Hillier L   +2 more
core  

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Whole genome sequencing in oesophageal adenocarcinoma unmasks potential precision therapies. [PDF]

BMC Cancer
Sharma S, Wong HY, Johnston RL, Koufariotis LT, Wood S, Hollway G, Aoude LG, Davidson AL, Pearson JV, Lin FP, Barbour AP, Waddell N.   +11 more
europepmc   +1 more source

Mitochondrial Genome Sequencing and Phylogenetic Analysis of <i>Myotis pequinius</i> and <i>M. chinensis</i>. [PDF]

Ecol Evol
Wang X, Cao X, Guan H, Feng H, Liu S.
europepmc   +1 more source

Low-pass whole-genome sequencing reveals genomic diversity and ecotype-specific adaptation in indigenous Tigrayan chickens. [PDF]

Sci Rep
Gebru G, Belay G, Zegeye T, Dessie T, Birhanie M, Zenebe M, Salim B, Katrina M, Hanotte O, Vallejo-Trujillo A.   +9 more
europepmc   +1 more source

Genome sequencing identifies monogenic causes in adults with metabolic diseases. [PDF]

J Endocr Soc
Okur V, Marcus A, Falcone JN, Hurd MA, Stewart SL, Claudio K, Manohar J, Dealla F, Kumar S, Yeung M, Dakin G, Bellorin-Marin O, Afaneh C, Hudgins LC, Wei E, Gingras L, King A, Tung J, Rehman AU, Thomas-Wilson A, Guha S, Abhyankar A, Wilson AL, Khan SY, Srinivasa ST, Phadke S, Krithivasan P, Nava C, Chen S, Smith R, MacDonald TY, Ritter MJ, Alonso LC, Elemento O, Udler MS, Peña JM, Jobanputra V, Goncalves MD.   +37 more
europepmc   +1 more source

Accelerated long-read variant calling with Clair3 for whole-genome sequencing. [PDF]

Bioinformatics
Zheng Z, He M, Yu X, Li J, Chen L, Wong AOK, Zhang J, Zhou Y, Luo R.   +8 more
europepmc   +1 more source