Results 261 to 270 of about 1,556,351 (302)
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Interpreting Whole-Genome Sequencing
JAMA, 2014We believe that the report of the yield and interpretability of clinical whole-genome sequencing by Dr Dewey and colleagues1 is unduly pessimistic about the present and future efficacy of this molecular genetic technology in clinical medicine. Their experience of low coverage of key disease genes, poor nucleotide-calling reproducibility, low diagnostic
Wayne W, Grody +2 more
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Genome sequencing: Illuminating the sunflower genome
Nature Plants, 2017A high-quality sunflower genome provides insight into Asterid genome evolution. Moreover, integrative analyses based on quantitative genetics, expression and diversity data uncover the gene networks and candidate genes for oil metabolism and flowering time, two important agronomic traits for sunflowers.
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Toward nanoscale genome sequencing
Trends in Biotechnology, 2007This article reports on the state-of-the-art technologies that sequence DNA using miniaturized devices. The article considers the miniaturization of existing technologies for sequencing DNA and the opportunities for cost reduction that 'on-chip' devices can deliver.
Declan, Ryan +4 more
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2014
The current Lotus japonicus reference genome sequence is based on a hybrid assembly of Sanger TAC/BAC, Sanger shotgun and Illumina shotgun sequencing data generated from the Miyakojima-MG20 accession. It covers nearly all expressed L. japonicus genes and has been annotated mainly based on transcriptional evidence.
Sato, Shusei, Andersen, Stig Uggerhøj
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The current Lotus japonicus reference genome sequence is based on a hybrid assembly of Sanger TAC/BAC, Sanger shotgun and Illumina shotgun sequencing data generated from the Miyakojima-MG20 accession. It covers nearly all expressed L. japonicus genes and has been annotated mainly based on transcriptional evidence.
Sato, Shusei, Andersen, Stig Uggerhøj
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Science, 1997
The human genome project is at the halfway point. The genomes of 11 microbes, Escherichia coli , and yeast are finished, yet the human genome is only 2 percent finished. The scale-up to finish by 2005 presents a significant challenge.
L, Rowen, G, Mahairas, L, Hood
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The human genome project is at the halfway point. The genomes of 11 microbes, Escherichia coli , and yeast are finished, yet the human genome is only 2 percent finished. The scale-up to finish by 2005 presents a significant challenge.
L, Rowen, G, Mahairas, L, Hood
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Genome Sequencing and Assembly
2011Decoding the genome sequence is becoming a fundamental tool for molecular, genetic, and genomic studies. This chapter reviews the history of DNA sequencing and technical principles of different sequencing platforms, and compares the strengths and weaknesses of different techniques for high-throughput genome sequencing applications are compared. It also
Manfred G, Grabherr +2 more
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Malaria Genome Sequencing Project.
2000Abstract : The objectives of this 5-year Cooperative Agreement between TICR and the Malaria Program, NMPC, were to: Specific Aim 1, sequence 3.5 Mb of P. ralciparum genomic DNA; Specific Aim 2, annotate the sequence; Specific Aim 3, release the information to the scientific community.
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