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Direct whole-genome sequencing of Coxiella burnetii from environmental samples using a two-step selective enrichment approach. [PDF]

open access: yesPLoS Negl Trop Dis
Bezruchko M   +11 more
europepmc   +1 more source
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The Sequence of the Human Genome

Science, 2001
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months from 27,271,853 high-quality sequence reads (5.11-fold coverage of the genome) from both ends of plasmid clones made from the DNA of ...
Venter, J. Craig   +205 more
openaire   +3 more sources

Sequencing the Human Genome

Science, 1997
The human genome project is at the halfway point. The genomes of 11 microbes, Escherichia coli , and yeast are finished, yet the human genome is only 2 percent finished. The scale-up to finish by 2005 presents a significant challenge.
L, Rowen, G, Mahairas, L, Hood
openaire   +4 more sources

Genome Sequencing

2016
Genome sequencing is an important step toward correlating genotypes with phenotypic characters. Sequencing technologies are important in many fields in the life sciences, including functional genomics, transcriptomics, oncology, evolutionary biology, forensic sciences, and many more. The era of sequencing has been divided into three generations.
Mansi, Verma   +2 more
openaire   +2 more sources

Genome Sequencing

2018
Strategies for sequencing fungal genomes on next-generation sequencing (NGS) platforms depend on the characteristics of the genome of the targeted species, quantity and quality of the genomic DNA, and cost considerations. Massively parallel sequencing with sequencing by synthesis (SBS) approach by Illumina produces terabases of short read sequences (i ...
Yuko, Yoshinaga   +3 more
openaire   +2 more sources

Genome Sequencing and Genomics

2014
This chapter explores issues related to Legionella genomics. A critical breakthrough in this area recently occurred with the determination of the genome sequences of three clinical, serogroup 1 isolates of Legionella pneumophila subsp. pneumophila. The three strains are L. pneumophila Paris, Lens and Philadelphia-1.
Carmen Buchrieser   +3 more
openaire   +1 more source

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