Results 271 to 280 of about 1,118,249 (314)
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2016
Genome sequencing is an important step toward correlating genotypes with phenotypic characters. Sequencing technologies are important in many fields in the life sciences, including functional genomics, transcriptomics, oncology, evolutionary biology, forensic sciences, and many more. The era of sequencing has been divided into three generations.
Mansi, Verma +2 more
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Genome sequencing is an important step toward correlating genotypes with phenotypic characters. Sequencing technologies are important in many fields in the life sciences, including functional genomics, transcriptomics, oncology, evolutionary biology, forensic sciences, and many more. The era of sequencing has been divided into three generations.
Mansi, Verma +2 more
openaire +2 more sources
2018
Strategies for sequencing fungal genomes on next-generation sequencing (NGS) platforms depend on the characteristics of the genome of the targeted species, quantity and quality of the genomic DNA, and cost considerations. Massively parallel sequencing with sequencing by synthesis (SBS) approach by Illumina produces terabases of short read sequences (i ...
Yuko, Yoshinaga +3 more
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Strategies for sequencing fungal genomes on next-generation sequencing (NGS) platforms depend on the characteristics of the genome of the targeted species, quantity and quality of the genomic DNA, and cost considerations. Massively parallel sequencing with sequencing by synthesis (SBS) approach by Illumina produces terabases of short read sequences (i ...
Yuko, Yoshinaga +3 more
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Genome Sequencing and Genomics
2014This chapter explores issues related to Legionella genomics. A critical breakthrough in this area recently occurred with the determination of the genome sequences of three clinical, serogroup 1 isolates of Legionella pneumophila subsp. pneumophila. The three strains are L. pneumophila Paris, Lens and Philadelphia-1.
Carmen Buchrieser +3 more
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Science, 1996
I have learned that the U.S. National Institutes of Health (NIH) is to support a program to sequence the genome of Microbacterium tuberculosis . While this information is desperately needed to advance studies that could provide essential clues to the pathogenesis and effective treatment of tuberculosis, I am dismayed and disappointed by the decision ...
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I have learned that the U.S. National Institutes of Health (NIH) is to support a program to sequence the genome of Microbacterium tuberculosis . While this information is desperately needed to advance studies that could provide essential clues to the pathogenesis and effective treatment of tuberculosis, I am dismayed and disappointed by the decision ...
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Current Opinion in Plant Biology, 2004
Sequencing of complex genomes can be accomplished by enriching shotgun libraries for genes. In maize, gene-enrichment by copy-number normalization (high C(0)t) and methylation filtration (MF) have been used to generate up to two-fold coverage of the gene-space with less than 1 million sequencing reads.
Robert A, Martienssen +3 more
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Sequencing of complex genomes can be accomplished by enriching shotgun libraries for genes. In maize, gene-enrichment by copy-number normalization (high C(0)t) and methylation filtration (MF) have been used to generate up to two-fold coverage of the gene-space with less than 1 million sequencing reads.
Robert A, Martienssen +3 more
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Genome Sequencing and Annotation
2003The availability of complete microbial genome sequences enormously facilitates experimental molecular investigations of the respective organisms by providing complete lists of genes, their genetic contexts, and their predicted functions. This can be used in a number of ways to focus studies on bacterial pathogenesis and also vaccine development (1,2 ...
A C, Jeffries, N J, Saunders, D W, Hood
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2010
Whole genome sequencing provides the most comprehensive collection of an individual's genetic variation. With the falling costs of sequencing technology, we envision paradigm shift from microarray-based genotyping studies to whole genome sequencing. We review methodologies for whole genome sequencing.
Pauline C, Ng, Ewen F, Kirkness
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Whole genome sequencing provides the most comprehensive collection of an individual's genetic variation. With the falling costs of sequencing technology, we envision paradigm shift from microarray-based genotyping studies to whole genome sequencing. We review methodologies for whole genome sequencing.
Pauline C, Ng, Ewen F, Kirkness
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Nature Reviews Genetics, 2001
Genome sequencing projects have been undertaken in one of three ways: in a purpose-built and professionally staffed genome centre, by a small number of traditional research laboratories or by an extensive network of traditional research laboratories that are linked by the Internet.
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Genome sequencing projects have been undertaken in one of three ways: in a purpose-built and professionally staffed genome centre, by a small number of traditional research laboratories or by an extensive network of traditional research laboratories that are linked by the Internet.
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Genome Sequencing and Assembly
2011Decoding the genome sequence is becoming a fundamental tool for molecular, genetic, and genomic studies. This chapter reviews the history of DNA sequencing and technical principles of different sequencing platforms, and compares the strengths and weaknesses of different techniques for high-throughput genome sequencing applications are compared. It also
Manfred G, Grabherr +2 more
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Whole-Exome/Genome Sequencing and Genomics
Pediatrics, 2013As medical genetics has progressed from a descriptive entity to one focused on the functional relationship between genes and clinical disorders, emphasis has been placed on genomics. Genomics, a subelement of genetics, is the study of the genome, the sum total of all the genes of an organism.
Wayne W, Grody +2 more
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