Results 21 to 30 of about 2,337,583 (311)

Of Mice and Genome Sequence [PDF]

open access: yesCell, 2001
Availability of the mouse genome sequence will have a major impact on the study of vertebrate evolution, mammalian biology, and animal models of human disease. Resources to explore genome biology in mice will maximize the effect of this watershed event.
Hamilton, B A, Frankel, W N
openaire   +2 more sources

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle [PDF]

open access: yes, 2015
Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus.
Magee, DA   +54 more
core   +1 more source

GENESPACE tracks regions of interest and gene copy number variation across multiple genomes

open access: yeseLife, 2022
The development of multiple chromosome-scale reference genome sequences in many taxonomic groups has yielded a high-resolution view of the patterns and processes of molecular evolution.
John T Lovell   +8 more
doaj   +1 more source

Reassociation kinetics-based approach for partial genome sequencing of the cattle tick, Rhipicephalus (Boophilus) microplus [PDF]

open access: yes, 2010
Background: The size and repetitive nature of the Rhipicephalus microplus genome makes obtaining a full genome sequence fiscally and technically problematic. To selectively obtain gene-enriched regions of this tick's genome, Cot filtration was performed,
Matthew Bellgard   +21 more
core   +1 more source

Routine use of microbial whole genome sequencing in diagnostic and public health microbiology [PDF]

open access: yes, 2012
This work is partly supported by funding from the Medical Research Council, the European Developing Country Clinical Trials Partnership, the Global Alliance for TB Drug Development, and the European Union.Whole genome sequencing (WGS) promises to be ...
Holden, MTG   +43 more
core   +2 more sources

Four chromosome scale genomes and a pan-genome annotation to accelerate pecan tree breeding

open access: yesNature Communications, 2021
Pecan is an important specialty crop that has experienced extensive interspecific hybridization and nearly-obligate outcrossing. Here, the authors assemble diploid genomes of four outbred genotypes, identify interspecific introgressions through ...
John T. Lovell   +34 more
doaj   +1 more source

Application of massive parallel sequencing to whole genome SNP discovery in the porcine genome [PDF]

open access: yes, 2009
Background Although the Illumina 1 G Genome Analyzer generates billions of base pairs of sequence data, challenges arise in sequence selection due to the varying sequence quality.
Kerstens Hindrik HD   +24 more
core   +1 more source

Identifying predictive features of Clostridium difficile infection recurrence before, during, and after primary antibiotic treatment

open access: yesMicrobiome, 2017
Background Colonization by the pathogen Clostridium difficile often occurs in the background of a disrupted microbial community. Identifying specific organisms conferring resistance to invasion by C.
Sepideh Pakpour   +7 more
doaj   +1 more source

Hidden biases in germline structural variant detection

open access: yesGenome Biology, 2021
Background Genomic structural variations (SV) are important determinants of genotypic and phenotypic changes in many organisms. However, the detection of SV from next-generation sequencing data remains challenging.
Michael M. Khayat   +10 more
doaj   +1 more source

A Complete Mitochondrial Genome Sequence from a Mesolithic Wild Aurochs (Bos primigenius) [PDF]

open access: yes, 2010
Background The derivation of domestic cattle from the extinct wild aurochs (Bos primigenius) has been well-documented by archaeological and genetic studies.
Finlay Emma K.   +53 more
core   +1 more source

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