Results 11 to 20 of about 1,118,249 (314)
Proceedings of the National Academy of Sciences, 1984 Unique DNA sequences can be determined directly from mouse genomic DNA. A denaturing gel separates by size mixtures of unlabeled DNA fragments from complete restriction and partial chemical cleavages of the entire genome. These lanes of DNA are transferred and UV-crosslinked to nylon membranes.
Church, George, Gilbert, Walter
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The Genome Sequence DataBase [PDF]
Nucleic Acids Research, 2000 The Genome Sequence DataBase (GSDB) is a database of publicly available nucleotide sequences and their associated biological and bibliographic information. Several notable changes have occurred in the past year: GSDB stopped accepting data submissions from researchers; ownership of data submitted to GSDB was transferred to GenBank; sequence analysis ...
Carol Harger +8 more
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Sequencing the human genome [PDF]
Nature, 1986 The title of the report by R. Myerowitz and N. Hogikyan on page 1646 of the issue of 27 June was incorrect. It should have been "Different mutations in Ashkenazi Jews and non-Jewish French Canadians with Tay-Sachs disease."
J B, Walsh, J, Marks
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Sequencing technologies and genome sequencing [PDF]
Journal of Applied Genetics, 2011 The high-throughput - next generation sequencing (HT-NGS) technologies are currently the hottest topic in the field of human and animals genomics researches, which can produce over 100 times more data compared to the most sophisticated capillary sequencers based on the Sanger method.
Pareek, Chandra Shekhar +2 more
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Practical Neurology, 2021 The costs of whole-genome sequencing have rapidly decreased, and it is being increasingly deployed in large-scale clinical research projects and introduced into routine clinical care. This will lead to rapid diagnoses for patients with genetic disease but also introduces uncertainty because of the diversity of human genomes and the potential ...
Huw R Morris, Henry Houlden, James Polke
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Pig genome sequence - analysis and publication strategy [PDF]
, 2010 Background The pig genome is being sequenced and characterised under the auspices of the Swine Genome Sequencing Consortium. The sequencing strategy followed a hybrid approach combining hierarchical shotgun sequencing of BAC clones and whole genome ...
Fredholm, M. +49 more
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The Sequence of the Human Genome [PDF]
Clinical Chemistry, 2015 A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months from 27,271,853 high-quality sequence reads (5.11-fold coverage of the genome) from both ends of plasmid clones made from the DNA of ...
J Craig, Venter +2 more
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Genome sequences: Genome sequence of a model prokaryote [PDF]
Current Biology, 1997 The complete Escherichia coli genome sequence is now known; it should greatly facilitate the analysis of other genomes, but a lot remains to be learnt about E. coli itself. About half the genes were previously uncharacterized, but expanding databases and improving analysis methods will help predict their functions.
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Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle [PDF]
, 2015 Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus.
Magee, DA +54 more
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GENESPACE tracks regions of interest and gene copy number variation across multiple genomes
eLife, 2022 The development of multiple chromosome-scale reference genome sequences in many taxonomic groups has yielded a high-resolution view of the patterns and processes of molecular evolution.
John T Lovell +8 more
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