Results 31 to 40 of about 2,337,583 (311)

The South Asian Genome [PDF]

open access: yes, 2014
The genetic sequence variation of people from the Indian subcontinent who comprise one-quarter of the world's population, is not well described. We carried out whole genome sequencing of 168 South Asians, along with whole-exome sequencing of 147 South ...
Li Yingrui   +200 more
core   +1 more source

Multi-Platform Next-Generation Sequencing of the Domestic Turkey (Meleagris gallopavo): Genome Assembly and Analysis [PDF]

open access: yes, 2010
A synergistic combination of two next-generation sequencing platforms with a detailed comparative BAC physical contig map provided a cost-effective assembly of the genome sequence of the domestic turkey (Meleagris gallopavo).
Kent M Reed   +405 more
core   +1 more source

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts. [PDF]

open access: yes, 2014
Plasmodium falciparum causes most human malaria deaths, having prehistorically evolved from parasites of African Great Apes. Here we explore the genomic basis of P.
Conway, David J   +30 more
core   +1 more source

Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy [PDF]

open access: yes, 2014
Whole-genome sequencing of the four isolates used in this study was supported by Wellcome Trust grant 098051, awarded to the Wellcome Trust Sanger Institute.
Theobald, V   +38 more
core   +1 more source

Pre-sequencing assessment of RNA-Seq library quality using real-time qPCR

open access: yesBioTechniques
RNA sequencing (RNA-Seq) is an essential assay for studying transcriptome profiling. Ribosomal RNA (rRNA) comprises more than 80–90% of total cellular RNA; efficient removal is essential for accurately capturing transcriptomes, particularly to sequence ...
Kavya Kottapalli   +13 more
doaj   +1 more source

Structural variation in the chicken genome identified by paired-end next-generation DNA sequencing of reduced representation libraries [PDF]

open access: yes, 2011
Background Variation within individual genomes ranges from single nucleotide polymorphisms (SNPs) to kilobase, and even megabase, sized structural variants (SVs), such as deletions, insertions, inversions, and more complex rearrangements.
Kerstens Hindrik HD   +17 more
core   +2 more sources

Genomic sequencing in cancer [PDF]

open access: yesCancer Letters, 2013
Genomic sequencing has provided critical insights into the etiology of both simple and complex diseases. The enormous reductions in cost for whole genome sequencing have allowed this technology to gain increasing use. Whole genome analysis has impacted research of complex diseases including cancer by allowing the systematic analysis of entire genomes ...
Musaffe, Tuna, Christopher I, Amos
openaire   +2 more sources

Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus)

open access: yesBMC Biology, 2017
Background The de novo assembly of repeat-rich mammalian genomes using only high-throughput short read sequencing data typically results in highly fragmented genome assemblies that limit downstream applications.
Peter A. Larsen   +19 more
doaj   +1 more source

Population genomics and climate adaptation of a C4 perennial grass, Panicum hallii (Poaceae)

open access: yesBMC Genomics, 2018
Background Understanding how and why genetic variation is partitioned across geographic space is of fundamental importance to understanding the nature of biological species.
Billie A. Gould   +7 more
doaj   +1 more source

Harmonization of supervised machine learning practices for efficient source attribution of Listeria monocytogenes based on genomic data

open access: yesBMC Genomics, 2023
Background Genomic data-based machine learning tools are promising for real-time surveillance activities performing source attribution of foodborne bacteria such as Listeria monocytogenes.
Pierluigi Castelli   +6 more
doaj   +1 more source

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