Results 31 to 40 of about 1,556,351 (302)

ForestQC: Quality control on genetic variants from next-generation sequencing data using random forest. [PDF]

, 2019
Next-generation sequencing technology (NGS) enables the discovery of nearly all genetic variants present in a genome. A subset of these variants, however, may have poor sequencing quality due to limitations in NGS or variant callers.
Coppola, Giovanni, Freimer, Nelson B, Hwang, Sungoo, Jew, Brandon, Li, Jiajin, Sul, Jae Hoon, Zhan, Lingyu   +6 more
core   +1 more source

Population genomics and climate adaptation of a C4 perennial grass, Panicum hallii (Poaceae)

BMC Genomics, 2018
Background Understanding how and why genetic variation is partitioned across geographic space is of fundamental importance to understanding the nature of biological species.
Billie A. Gould, Juan Diego Palacio-Mejia, Jerry Jenkins, Sujan Mamidi, Kerrie Barry, Jeremy Schmutz, Thomas E. Juenger, David B. Lowry   +7 more
doaj   +1 more source

Draft Genome of Pseudomonas sp. Strain 11/12A, Isolated from Lake Washington Sediment. [PDF]

, 2015
We announce here the genome sequencing of Pseudomonas sp. strain 11/12A from Lake Washington sediment. From the genome content, a versatile lifestyle is predicted but not one of bona fide methylotrophy.
Chistoserdova, Ludmila, McTaggart, Tami L, Shapiro, Nicole, Woyke, Tanja   +3 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Comparative genomics of the miniature wasp and pest control agent Trichogramma pretiosum

BMC Biology, 2018
Background Trichogrammatids are minute parasitoid wasps that develop within other insect eggs. They are less than half a millimeter long, smaller than some protozoans.
Amelia R. I. Lindsey, Yogeshwar D. Kelkar, Xin Wu, Dan Sun, Ellen O. Martinson, Zhichao Yan, Paul F. Rugman-Jones, Daniel S. T. Hughes, Shwetha C. Murali, Jiaxin Qu, Shannon Dugan, Sandra L. Lee, Hsu Chao, Huyen Dinh, Yi Han, Harsha Vardhan Doddapaneni, Kim C. Worley, Donna M. Muzny, Gongyin Ye, Richard A. Gibbs, Stephen Richards, Soojin V. Yi, Richard Stouthamer, John H. Werren   +23 more
doaj   +1 more source

SARS-CoV-2 surveillance in Italy through phylogenomic inferences based on Hamming distances derived from pan-SNPs, -MNPs and -InDels

BMC Genomics, 2021
Background Faced with the ongoing global pandemic of coronavirus disease, the ‘National Reference Centre for Whole Genome Sequencing of microbial pathogens: database and bioinformatic analysis’ (GENPAT) formally established at the ‘Istituto ...
Adriano Di Pasquale, Nicolas Radomski, Iolanda Mangone, Paolo Calistri, Alessio Lorusso, Cesare Cammà   +5 more
doaj   +1 more source

Sequencing the banana genome (W069) [PDF]

, 2011
Bananas (Musa) are the fourth most important crop in developing countries. They are important as an export crop but also play a major role in local food security. Crops of Musa are susceptible to an ever increasing range of diseases requiring massive use
D'Hont, Angélique, Wincker, Patrick
core  

Genome sequences: Genome sequence of a model prokaryote [PDF]

Current Biology, 1997
The complete Escherichia coli genome sequence is now known; it should greatly facilitate the analysis of other genomes, but a lot remains to be learnt about E. coli itself. About half the genes were previously uncharacterized, but expanding databases and improving analysis methods will help predict their functions.
openaire   +2 more sources

Harmonization of supervised machine learning practices for efficient source attribution of Listeria monocytogenes based on genomic data

BMC Genomics, 2023
Background Genomic data-based machine learning tools are promising for real-time surveillance activities performing source attribution of foodborne bacteria such as Listeria monocytogenes.
Pierluigi Castelli, Andrea De Ruvo, Andrea Bucciacchio, Nicola D’Alterio, Cesare Cammà, Adriano Di Pasquale, Nicolas Radomski   +6 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source