Results 101 to 110 of about 3,499,703 (265)

Aspergillus flavus NRRL 3357 wt AflW60-3 Resequencing genome sequencing

, 2016
Genome sequencing of Aspergillus flavus strain to assess the consequences of the elimination of the NHEJ DNA repair mechanisms on the genome stability and fungal ...
DOE Joint Genome Institute (17854997)
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Aspergillus flavus NRRL 3357 wt AflW60-8 Resequencing genome sequencing

, 2016
Genome sequencing of Aspergillus flavus strain to assess the consequences of the elimination of the NHEJ DNA repair mechanisms on the genome stability and fungal ...
DOE Joint Genome Institute (17854997)
core  

MAP3K13-232aa encoded by circMAP3K13 enhances cisplatin-induced pyroptosis by directly binding to IKKα in gastric adenocarcinoma

Cell Death and Disease
Gastric cancer (GC) is one of the most common and lethal malignancies in developing countries, with particularly high prevalence in China. Circular RNAs (circRNAs) have garnered increasing attention for their roles in disease pathogenesis. While circRNAs
Kaining Du, Xiaojing Zhang, Ying Qin, Huizhen Ma, Chuhan Bing, Shiqi Deng, Yang Chen, Jiequan Qin, Shanshan Chang, Siyu Xiao, Lehua Peng, Xiaoya Xie, Xianling Feng, Xianli Fu, Yanjie Wei, Xinmin Fan, Hassan Ashktorab, Duane Smoot, Zhe Jin, Yin Peng   +19 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Aspergillus flavus NRRL 3357 wt AflW60-6 Resequencing genome sequencing

, 2016
Genome sequencing of Aspergillus flavus strain to assess the consequences of the elimination of the NHEJ DNA repair mechanisms on the genome stability and fungal ...
DOE Joint Genome Institute (17854997)
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Aspergillus flavus NRRL 3357 wt AflW60-5 Resequencing genome sequencing

, 2016
Genome sequencing of Aspergillus flavus strain to assess the consequences of the elimination of the NHEJ DNA repair mechanisms on the genome stability and fungal ...
DOE Joint Genome Institute (17854997)
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Aspergillus flavus NRRL 3357 wt AflW60-4 Resequencing genome sequencing

, 2016
Genome sequencing of Aspergillus flavus strain to assess the consequences of the elimination of the NHEJ DNA repair mechanisms on the genome stability and fungal ...
DOE Joint Genome Institute (17854997)
core