Results 1 to 10 of about 1,458,308 (328)

Extensive co-binding and rapid redistribution of NANOG and GATA6 during emergence of divergent lineages

Nature Communications, 2022
The authors show that the transcription factors NANOG and GATA6 co-bind the same enhancers in common progenitors before divergent epiblast and primitive endoderm lineages emerge.
Joyce J. Thompson, Daniel J. Lee, Apratim Mitra, Sarah Frail, Ryan K. Dale, Pedro P. Rocha   +5 more
doaj   +1 more source

Non-negligible Occurrence of Errors in Gender Description in Public Data Sets [PDF]

Genomics & Informatics, 2016
Due to advances in omics technologies, numerous genome-wide studies on human samples have been published, and most of the omics data with the associated clinical information are available in public repositories, such as Gene Expression Omnibus and ...
Jong Hwan Kim, Jong-Luyl Park, Seon-Young Kim   +2 more
doaj   +1 more source

Magnetically accelerated thermal energy storage within Fe3O4‐anchored MXene‐based phase change materials

Aggregate, 2023
Inherent weak photon‐capturing ability is a long‐standing bottleneck for pristine phase change materials (PCMs) in photothermal conversion application.
Yan Gao, Zhaodi Tang, Xiao Chen, Jiamin Yan, Yu Jiang, Jianhang Xu, Zhang Tao, Lei Wang, Zhimeng Liu, Ge Wang   +9 more
doaj   +1 more source

Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors

Nature Communications, 2023
Cohesin regulates gene expression through context-specific chromatin folding mechanisms such as enhancer–promoter looping and topologically associating domain (TAD) formation by cooperating with factors such as cohesin loaders and the insulation factor ...
Ryuichiro Nakato, Toyonori Sakata, Jiankang Wang, Luis Augusto Eijy Nagai, Yuya Nagaoka, Gina Miku Oba, Masashige Bando, Katsuhiko Shirahige   +7 more
doaj   +1 more source

Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures

Cell Reports, 2020
Summary: To study the development of the human retina, we use single-cell RNA sequencing (RNA-seq) at key fetal stages and follow the development of the major cell types as well as populations of transitional cells.
Akshayalakshmi Sridhar, Akina Hoshino, Connor R. Finkbeiner, Alex Chitsazan, Li Dai, Alexandra K. Haugan, Kayla M. Eschenbacher, Dana L. Jackson, Cole Trapnell, Olivia Bermingham-McDonogh, Ian Glass, Thomas A. Reh   +11 more
doaj   +1 more source

Aromatic compounds‐mediated synthesis of anatase‐free hierarchical TS‐1 zeolite: Exploring design strategies via machine learning and enhanced catalytic performance

Aggregate, 2023
Simultaneous achievement of constructing mesopores and eliminating anatase is a long‐term pursuit for enhancing the catalytic performance of TS‐1. Here, we developed an aromatic compounds‐mediated synthesis method to prepare anatase‐free and hierarchical
Chang'an Wang, Guoqing An, Jing Lin, Xiaowei Zhang, Zhiyuan Liu, Yibin Luo, Siqi Liu, Zhixiang Cheng, Tingting Guo, Hongyi Gao, Ge Wang, Xingtian Shu   +11 more
doaj   +1 more source

Integrating multiple energy storage in 1D–2D bridged array carbon‐based phase change materials

SusMat, 2023
In response to global energy scarcity, frontiers in multifunctional composite phase change materials (PCMs) with photo‐/electro‐/magnetothermal triggers show great potential in multiple energy utilization. However, most available composite PCM candidates
Xiao Chen, Jianhang Xu, Yang Li, Yan Gao, Ge Wang   +4 more
doaj   +1 more source

NFATc1 regulates the transcription of DNA damage-induced apoptosis suppressor

Data in Brief, 2015
DNA damage induced apoptosis suppressor (DDIAS), or human Noxin (hNoxin), is strongly expressed in lung cancers. DDIAS knockdown induced apoptosis in non-small cell lung carcinoma A549 cells in response to DNA damage, indicating DDIAS as a potential ...
Joo-Young Im, Kang-Woo Lee, Kyoung-Jae Won, Bo-Kyung Kim, Hyun Seung Ban, Sung-Hoon Yoon, Young-Ju Lee, Young-Joo Kim, Kyung-Bin Song, Misun Won   +9 more
doaj   +1 more source

Immune Regulation in Time and Space: The Role of Local- and Long-Range Genomic Interactions in Regulating Immune Responses

Frontiers in Immunology, 2021
Mammals face and overcome an onslaught of endogenous and exogenous challenges in order to survive. Typical immune cells and barrier cells, such as epithelia, must respond rapidly and effectively to encountered pathogens and aberrant cells to prevent ...
Liam P. Devenish, Musa M. Mhlanga, Musa M. Mhlanga, Musa M. Mhlanga, Yutaka Negishi, Yutaka Negishi, Yutaka Negishi   +6 more
doaj   +1 more source

Alzheimer's disease and HIV associated dementia related genes: I. location and function. [PDF]

, 2008
Alzheimer's disease (AD), the most common cause of dementia, has few clinical similarities to HIV-1-associated dementia (HAD). However, genes were identified related among these dementias.
Chiappelli, Francesco, Kayathri, Rajarathinam, Levine, Andrew, Minagar, Alireza, Rodriguez, Hector E, Shapshak, Paul   +5 more
core   +3 more sources