Results 1 to 10 of about 14,332,059 (405)
HPV16 and HPV18 Genome Structure, Expression, and Post-Transcriptional Regulation
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high-risk HPVs, are responsible for ~70% of all HPV-related cervical cancers and head and ...
Lulu Yu, V. Majerciak, Zhi-Ming Zheng
semanticscholar +1 more source
MyoD is a 3D genome structure organizer for muscle cell identity
The genome exists as an organized, three-dimensional (3D) dynamic architecture, and each cell type has a unique 3D genome organization that determines its cell identity.
Rui-chen Wang+19 more
semanticscholar +1 more source
SARS-CoV-2: from its discovery to genome structure, transcription, and replication
SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits significant ...
Ayslan C Brant+4 more
semanticscholar +1 more source
The authors show that the transcription factors NANOG and GATA6 co-bind the same enhancers in common progenitors before divergent epiblast and primitive endoderm lineages emerge.
Joyce J. Thompson+5 more
doaj +1 more source
Epigenomic landscape and 3D genome structure in pediatric high-grade glioma
Distinct genomic structural variations are found in pediatric high-grade glioma, affecting tumor gene expression. Pediatric high-grade gliomas (pHGGs), including glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), are morbid brain ...
Juan Wang+7 more
semanticscholar +1 more source
Non-negligible Occurrence of Errors in Gender Description in Public Data Sets [PDF]
Due to advances in omics technologies, numerous genome-wide studies on human samples have been published, and most of the omics data with the associated clinical information are available in public repositories, such as Gene Expression Omnibus and ...
Jong Hwan Kim+2 more
doaj +1 more source
Generation of dynamic three-dimensional genome structure through phase separation of chromatin
Three-dimensional genome structure and dynamics play critical roles in regulating DNA functions. Flexible chromatin structure and movements suggested that the genome is dynamically phase-separated to form A (active) and B (inactive) compartments in ...
Shin Fujishiro, Masaki Sasai
semanticscholar +1 more source
Inherent weak photon‐capturing ability is a long‐standing bottleneck for pristine phase change materials (PCMs) in photothermal conversion application.
Yan Gao+9 more
doaj +1 more source
Coronaviruses: genome structure, replication, and pathogenesis.
The recent emergence of a novel coronavirus (2019-nCoV), which caused an outbreak of unusual viral pneumonia in tens of people in Wuhan, a central city of China, restated the risk of coronaviruses posed to public health.
Yu Chen, Qianyun Liu, D. Guo
semanticscholar +1 more source
Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer
Muscle-invasive bladder cancers are characterized by their distinct expression of luminal and basal genes, which could be used to predict key clinical features such as disease progression and overall survival.
T. Iyyanki+20 more
semanticscholar +1 more source