Results 111 to 120 of about 1,403,931 (355)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2019 Syzygium forrestii Merr. et Perry is an evergreen broad-leaved tree, 8–15 metres tall. It is mainly distributed in the Southwest of China (Nu river valley to Xishuangbanna area), growing from 800 to 2400 metres above sea level.
Xiao-Feng Zhang +5 more
doaj +1 more source
Mitochondrial DNA. Part B. Resources, 2020 The complete mitochondrial genome DNA sequence of Lepidotrigla kanagashira was 16,504 bp in length. It consists of 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes and one control region.
Wei Wang +7 more
doaj +1 more source
Comparison of hom(oe)ologous chromosome segments in the highly polyploid interspecific genome of sugarcane [PDF]
, 2013 Modern sugarcane cultivars (Saccharum spp.) present one of the most complex crop genome studied to date, mainly due to a very high degree of polyploidy (2n = 12x = 120), and an interspecific origin from two autopolyploid species, namely S.
Charron, Carine +5 more
core
Comparative Modeling in Structural Genomics [PDF]
Structure, 2008 The genome sequencing revolution has resulted in a dramatic increase in the demand for structural information, a demand that traditional structural biology is totally unable to meet. The chance that a sequenced protein domain will have an experimental structure is already near 0.1% and that ratio is falling fast.
openaire +3 more sources
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2020 Flueggea virosa is a tropical plant of the Phyllanthaceae family, which has high medicinal value. Here, we report and characterize the complete plastome of F. virosa.
Hong-Tao Wang +3 more
doaj +1 more source
DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. [PDF]
, 2019 Assembly of Kaposi's sarcoma-associated herpesvirus (KSHV) begins at a bacteriophage-like portal complex that nucleates formation of an icosahedral capsid with capsid-associated tegument complexes (CATCs) and facilitates translocation of an ∼150-kb dsDNA
Bi, Guo-Qiang +6 more
core
Global divergence of microbial genome sequences mediated by propagating fronts
, 2005 We model the competition between recombination and point mutation in microbial genomes, and present evidence for two distinct phases, one uniform, the other genetically diverse.
Berg +23 more
core +2 more sources