Results 141 to 150 of about 1,478,279 (326)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

The \u3cem\u3eChlamydomonas\u3c/em\u3e Genome Reveals the Evolution of Key Animal and Plant Functions [PDF]

, 2007
Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic ...
Abby Ngau, Wing Chi, Allmer, Jens, Balk, Janneke, Ball, Steven, Bisova, Katerina, Bowler, Chris, Brokstein, Peter, Cardol, Pierre, Cerutti, Heriberto, Chanfreau, Guillaume, Chen, Chong-Jian, Chen, Chun-Long, Cognat, Valerie, Croft, Martin T., Dent, Rachel, Dieckmann, Carol L., Dubchak, Inna, Dutcher, Susan, Elias, Mark, Fernández, Emilio, Ferris, Patrick, Fritz-Laylin, Lillian K., Fukuzawa, Hideya, Gendler, Karla, Gladyshev, Vadim N., González-Ballester, David, González-Halphen, Diego, Goodstein, David, Green, Pamela, Grigoriev, Igor V., Grimwood, Jane, Grossman, Arthur R., Hallmann, Armin, Hanikenne, Marc, Harris, Elizabeth H., Hauser, Charles, Hippler, Michael, Hornick, Leila, Huang, Y. Wayne, Inwood, William, Jabbari, Kamel, Jhaveri, Jinal, Jorgensen, Richard, Kalanon, Ming, Kapitonov, Vladimir V., Karpowicz, Steven J., Kuras, Richard, Lamb, Mary Rose, Ledford, Heidi, Lefebvre, Paul A., Lemaire, Stéphane D., Lindquist, Erika, Lobanov, Alexey V., Lohr, Martin, Long, Joanne C., Lucas, Susan M., Luo, Yigong, Manuell, Andrea, Marshall, Wallace F., Martinez, Diego, Maréchal-Drouard, Laurence, Mayfield, Stephen, Meier, Iris, Merchant, Sabeeha S., Mets, Laurens, Minagawa, Jun, Mittag, Maria, Mittelmeier, Telsa, Moroney, James V., Moseley, Jeffrey, Mueller-Roeber, Bernd, Napoli, Carolyn, Nedelcu, Aurora M., Nelson, David R., Niyogi, Krishna, Novoselov, Sergey V., Otillar, Bobby, Page, M. Dudley, Pan, Junmin, Paulsen, Ian T., Pazour, Greg, Poliakov, Alexander, Pootakham, Wirulda, Porter, Aaron, Prochnik, Simon E., Purton, Saul, Qu, Liang-Hu, Rajamani, Sathish, Ral, Jean-Philippe, Ren, Qinghu, Riaño-Pachón, Diego Mauricio, Riekhof, Wayne, Roje, Sanja, Rokhsar, Daniel S., Rose, Annkatrin, Rymarquis, Linda, Salamov, Asaf, Sanderfoot, Anton A., Sayre, Richard T., Schmutz, Jeremy, Schroda, Michael, Shapiro, Harris, Spalding, Martin H., Stahlberg, Eric, Stern, David, Szajkowski, Lukasz, Terauchi, Aimee M., Terry, Astrid, Umen, James, Vallon, Olivier, Werner, Gregory, Willows, Robert, Wilson, Nedra, Witman, George B., Yang, Pinfen, Zhou, Kemin, Zimmer, Sara Lana   +116 more
core   +1 more source

Structural genomics [PDF]

Current Biology, 1999
openaire   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The complete chloroplast genome sequence of Ampelopsis delavayana Planchon. ex Franch 1886 (Vitaceae)

Mitochondrial DNA. Part B. Resources
Ampelopsis delavayana Planchon. ex Franch 1886 is a plant with significant pharmacological effects and ornamental importance. This research unveiled the complete chloroplast (cp) genome sequence of A. delavayana.
Qun Hu, Yongjian Luo, Qing Li, Zhijun Deng, Jun Liu   +4 more
doaj   +1 more source

Epigenomics and the structure of the living genome [PDF]

, 2015
Nir Friedman, Oliver J. Rando
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Modified pegRNAs mitigate scaffold-derived prime editing by-products

Nature Communications
Prime editors (PEs) employ reverse transcriptase (RT) to install genomic edits using a template within the prime editing guide RNA (pegRNA). RT creates a 3’ genomic flap containing the intended edit. However, reverse transcription can continue beyond the
Panagiotis Antoniou, Louis Dacquay, Hanna Mårtensson, Katja Madeyski-Bengtson, Anna-Lena Loyd, Anna Shiriaeva, Euan Gordon, Salman Mustfa, George Thom, Pei-Pei Hsieh, Saša Šviković, Mike Firth, Nina Akrap, Marcello Maresca, Martin Peterka   +14 more
doaj   +1 more source