Results 181 to 190 of about 1,478,279 (326)

Conservation of bilaterian genome structure is the exception, not the rule. [PDF]

Genome Biol
Lewin TD, Liao IJ, Luo YJ.
europepmc   +1 more source

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

A diverse satellite DNA repertoire in <i>Limnoperna fortunei</i>: insights into genome structure and chromosomal organization. [PDF]

Front Mol Biosci
Castro JP, Degrandi TM, Leal AO, Ferreira Júnior AL, de Almeida MC, Artoni RF.   +5 more
europepmc   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Meiotic cohesin RAD21L shapes 3D genome structure and transcription in the male germline. [PDF]

Sci Adv
Marín-Gual L, Vara C, Sainz-Urruela R, Cuartero Y, Álvarez-González L, Felipe-Medina N, Garcia F, Llano E, Marti-Renom MA, Pendás AM, Ruiz-Herrera A.   +10 more
europepmc   +1 more source

Genome‐wide SNP assessment of contemporary European red deer genetic structure highlights the distinction of peripheral populations and the main admixture zones in Europe [PDF]

Juan Carranza, Javier Pérez‐González, Gabriel Anaya, Menno de Jong, Camilla Broggini, Frank E. Zachos, Allan D. McDevitt, Magdalena Niedziałkowska, Maciej Sykut, Sándor Csányi, Norber Bleier, Lázló Csirke, Knut H. Røed, Christine Saint‐Andrieux, Aurélie Barboiron, Araceli Gort‐Esteve, Jordi Ruiz‐Olmo, José Manuel Seoane, José A. Godoy, Paweł Mackiewicz, Eva de la Peña, Giovanni Vedel, S. Eryn McFarlane, Josephine M. Pemberton, A. Membrillo   +24 more
openalex   +1 more source

Inhibition of Chikungunya virus genome replication by targeting essential RNA structures within the virus genome

, 2023
Oliver Prosser, Nicola J. Stonehouse, Andrew Tuplin   +2 more
openalex   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Complete chloroplast genome sequence of Pachystachys lutea Nees: genome structure, adaptive evolution, and phylogenetic relationships. [PDF]

BMC Genom Data
Du C, Dong Y, Gao H, Fang T, Yue J, Zhang Y.   +5 more
europepmc   +1 more source

Detecting Heterogeneity in Population Structure Across the Genome in Admixed Populations [PDF]

, 2016
Caitlin McHugh, Lisa Brown, Timothy A. Thornton   +2 more
openalex   +1 more source