Results 271 to 280 of about 1,478,279 (326)

Imputation of 3D genome structure by genetic-epigenetic interaction modeling in mice. [PDF]

Elife
Kuffler L, Skelly DA, Czechanski A, Fortin HJ, Munger SC, Baker CL, Reinholdt LG, Carter GW.   +7 more
europepmc   +1 more source

Genome-wide identification and comprehensive characterization of the ADF gene family in Triticum monococcum L. subsp. aegilopoides with insights into structure, evolution and cold stress response [PDF]

Xin Liu, Minghu Zhang, Jian Su, Lei Wu, Mang Shen, Qi Wang, Yamei Zhuang, Lianquan Zhang, Haosheng Li, Gang Chen   +9 more
openalex   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Analysis of chloroplast genome structure and phylogeny of the traditional medicinal of Ardisia crispa (Myrsinaceae). [PDF]

Sci Rep
Ye J, Luo Q, Lang Y, Ding N, Jian YQ, Wu ZK, Wei SH, Yan FL.   +7 more
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

CTCF and cohesin cooperate to organize the 3D structure of the mammalian genome

, 2014
Laura Baranello, Fedor Kouzine, David Levens   +2 more
openalex   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Whole-genome sequencing revealed the population structure of Fujian chicken breeds [PDF]

Zhiming Zhu, Linli Zhang, Qingwu Xin, Li Li, Zhongwei Miao, Huang Qinlou, N. Zheng   +6 more
openalex   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Single-cell 3D genome structure reveals distinct human pluripotent states. [PDF]

Genome Biol
Li N, Jin K, Liu B, Yang M, Shi P, Heng D, Wang J, Liu L.   +7 more
europepmc   +1 more source