Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser +6 more
wiley +1 more source
Genome-wide association study (GWAS) and transcriptome analysis reveal new candidate genes for leaf size in alfalfa. [PDF]
Zhang Y +9 more
europepmc +1 more source
Identification of Gene Associated with Sweetness in Corn (Zea mays L.) by Genome-Wide Association Study (GWAS) and Development of a Functional SNP Marker for Predicting Sweet Corn. [PDF]
Ruanjaichon V +11 more
europepmc +1 more source
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) and language/reading difficulties frequently co‐occur. The extent of shared genetic architecture remains incompletely defined. We investigated genome‐wide overlap between ADHD and four core skills: word reading, nonword reading, spelling, and phoneme awareness.
Jinzhu Zhao +5 more
wiley +1 more source
Genome-wide association study (GWAS) identifies genetic loci controlling Distinctness, Uniformity, and Stability (DUS) traits in wheat. [PDF]
Zanella CM +11 more
europepmc +1 more source
Abstract Background Neurodevelopmental conditions often emerge early in life and have substantial genetic influences. There are significant genetic correlations between neurodevelopmental conditions, such as between autism spectrum disorder (Autism) and attention deficit‐hyperactivity disorder (ADHD), and they are listed together in diagnostic manuals.
Morgan James Morgan +3 more
wiley +1 more source
Genome-Wide Association Study (GWAS) for Linear Body Measurements of Sussex Cattle (Bos taurus) at Weaning and Yearling Age in South Africa. [PDF]
Bila L +4 more
europepmc +1 more source
Genome-Wide Association Study (GWAS) to Identify Salt-Tolerance QTLs Carrying Novel Candidate Genes in Rice During Early Vegetative Stage. [PDF]
Nayyeripasand L +3 more
europepmc +1 more source
Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang +3 more
wiley +1 more source
Integrating Genome-Wide Association Study (GWAS) and Marker-Assisted Selection for Enhanced Predictive Performance of Soybean Cold Tolerance. [PDF]
Xue Y +10 more
europepmc +1 more source

