Results 201 to 210 of about 188,588 (300)

Genome-wide association study (GWAS) approaches to sleep phenotypes [PDF]

, 2013
Patrick Sleiman, Michael March, Hakon Hakonarson   +2 more
openaire   +1 more source

Mediterranean Versus Western Diet Effects on Obesity Phenotypes and Adipose Tissue Transcriptional Profiles in Female Monkeys

Obesity, EarlyView.
ABSTRACT Objective Obesity, or excessive body fat, is a significant health risk factor. Western diets (WD) contribute to metabolic dysfunction and obesity, while Mediterranean diets (MD) improve metabolic health. This study examined the contrasting effects of WD versus MD on visceral and subcutaneous adipose tissues (VAT, SAT) using a randomized ...
Aya Jamal Abusheikha, Corbin S. C. Johnson, Noah Snyder‐Mackler, Kip D. Zimmerman, Brett M. Frye, Carol A. Shively, Thomas C. Register   +6 more
wiley   +1 more source

Translating Lung Function Genome-Wide Association Study (GWAS) Findings [PDF]

, 2016
A.K. Kheirallah, S. Miller, I.P. Hall, I. Sayers   +3 more
openaire   +1 more source

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

PM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang, Qing Kuang, Cheng Chen, Binru Wang, Wei Xiang, Xinming Li, Jianjiao Mou   +6 more
wiley   +1 more source

Resilience through diversity: The potential of modelling species and variety interactions to enhance resilience of production systems

PLANTS, PEOPLE, PLANET, EarlyView.
Agricultural production systems in the global North combine monocultures of specialised varieties and breeds with external interventions and inputs. Increasing the diversity of varieties, breeds and species may increase the system's resilience to external pressures through beneficial interactions.
Marinus J. M. Smulders, Gerbrich Bonekamp, Peter M. Bourke, Joukje Buiteveld, Janneke A. Dieleman, Anna Edlinger, Mark van Hoogdalem, Martina Huber, Jan ten Napel, Maarten van der Meer, Andries A. Temme, Pieter H. B. de Visser, Jorad de Vries, Sipke‐Joost Hiemstra   +13 more
wiley   +1 more source

Genome-wide Association Study (GWAS) for Mesocotyl Elongation in Rice (Oryza sativa L.) under Multiple Culture Conditions. [PDF]

Genes (Basel), 2019
Liu H, Zhan J, Li J, Lu X, Liu J, Wang Y, Zhao Q, Ye G.   +7 more
europepmc   +1 more source

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21 [PDF]

, 2018
Rubin, Joshua B.
core   +1 more source

Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Prostate cancer (PCa) is the most common malignant tumor in men, but the widely used prostate‐specific antigen (PSA) test has limited diagnostic accuracy. Research proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to
Jun Lu, Yan Lu, Takuro Kobayashi, Tsuyoshi Hachiya, Haruhiko Wakita, Yiming Jin, Yasunari Tanaka, Yoshihiro Ikehata, Masayoshi Nagata, Hisamitsu Ide, Shigeo Horie   +10 more
wiley   +1 more source

Conducting Genome-Wide Association Studies (GWAS): Epistasis Scenarios

, 2016
Philip Chester Cooley, Nathan Gaddis, Ralph E. Folsom, Diane Wagener   +3 more
openaire   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source