Results 281 to 290 of about 2,173,654 (348)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

A spectral component approach leveraging identity-by-descent graphs to address recent population structure in genomic analysis. [PDF]

Genome Res
Shemirani R, Belbin GM, Cullina S, Caggiano C, Gignoux CR, Zaitlen N, Kenny EE.   +6 more
europepmc   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Genomic analysis of Acinetobacter baumannii DUEMBL6 reveals diesel bioremediation potential and biosafety concerns. [PDF]

PLoS One
Uddin N, Prova MI, Billaha M, Anik TA, Uzzaman R, Haider N, Islam F, Akhter H, Begum A.   +8 more
europepmc   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Isolation and genomic analysis of secondary metabolism in cave Actinomycetota from biofilms and <i>Ceuthophilus</i>. [PDF]

MicroPubl Biol
Bachmann IO, Bachmann BO.
europepmc   +1 more source

Genomic analysis of the inbreeding load for body weight, carcass and reproductive traits in the Rubia Gallega beef cattle population. [PDF]

Genet Sel Evol
Hervás-Rivero C, López-Carbonell D, Sánchez-Díaz M, Varona L.   +3 more
europepmc   +1 more source

First genomic analysis of a strain of Ralstonia pseudosolanacearum isolated from Mayotte island. [PDF]

BMC Genom Data
Caly-Simbou E, Nomenjanahary MV, Javegny S, Boyer C, Chéron JJ, Ramin-Mangata S, Poussier S, Pecrix Y.   +7 more
europepmc   +1 more source

Editorial: Expert opinions in genomic analysis. [PDF]

Front Bioinform
Setubal JC, Paccanaro A.
europepmc   +1 more source

Integrated genomic analysis and CRISPRi implicates <i>EGFR</i> in Alzheimer's disease risk. [PDF]

NPJ Dement
Leung YY, Kuksa PP, Carter L, Cifello J, Greenfest-Allen E, Valladares O, Boateng L, Laub S, Tulina N, Moura S, Ramirez A, Celis K, Jin F, Feng R, Wang G, De Jager P, Vance JM, Wang L, Grant SFA, Schellenberg GD, Chesi A, Wang LS.   +21 more
europepmc   +1 more source