Genomic Analysis in the Age of Human Genome Sequencing [PDF]
Affordable genome sequencing technologies promise to revolutionize the field of human genetics by enabling comprehensive studies that interrogate all classes of genome variation, genome-wide, across the entire allele frequency spectrum. Ongoing projects worldwide are sequencing many thousands-and soon millions-of human genomes as part of various gene ...
Tuuli, Lappalainen +3 more
openaire +2 more sources
Genomic distance under gene substitutions [PDF]
Dias Vieira Braga M, Machado R, Ribeiro LC, Stoye J. Genomic distance under gene substitutions. BMC Bioinformatics. 2011;12(Suppl 9: Proc. of RECOMB-CG 2011): S8.Background: The distance between two genomes is often computed by comparing only the common
Stoye Jens +11 more
core +1 more source
Genomic Analysis of Clinical Multidrug Resistant E. coli in Nigerian Hospitals
Escherichia coli is an emerging nosocomial pathogen causing problems in health care settings. The management of human infections caused by multidrug resistant (MDR) E. coli poses substantial clinical challenges in hospitals.
Asuquo, B.S. +7 more
core +4 more sources
Gene expression is controlled at the transcriptional and post-transcriptional levels. The TACC2 gene was known to be associated with tumors but the control of its expression is unclear. We have reported that activity of the intronic promoter p10 of TACC2
Yosuke Ito +7 more
doaj +1 more source
Meeting report : 1st international functional metagenomics workshop May 7–8, 2012, St. Jacobs, Ontario, Canada [PDF]
This report summarizes the events of the 1st International Functional Metagenomics Workshop. The workshop was held on May 7 and 8 in St. Jacobs, Ontario, Canada and was focused on building a core international functional metagenomics community, exploring
David R. Rose +65 more
core +1 more source
Antimicrobial Peptides and Nanotechnology, Recent Advances and Challenges
Antimicrobial peptides are sequences of amino acids, which present activity against microorganisms. These peptides were discovered over 70 years ago, and are abundant in nature from soil bacteria, insects, amphibians to mammals and plants.
Lubhandwa S. Biswaro +7 more
doaj +1 more source
Robust single-cell DNA methylome profiling with snmC-seq2
Single-cell DNA methylome profiling allows the study of epigenomic heterogeneity in tissues but has been impeded by library quality. Here the authors demonstrate snmC-seq2 which improves mapping, throughput and library complexity.
Chongyuan Luo +17 more
doaj +1 more source
Sequencing data: A genomic network to monitor Earth
We propose that a network of genomic observatories should be established to take the planet's 'biological pulse'. We invite participants to assist in the shaping of this network (see genomicobservatories.org).
Field, D. +10 more
core +1 more source
Large-scale genetic variation of the symbiosis-required megaplasmid pSymA revealed by comparative genomic analysis of Sinorhizobium meliloti natural strains [PDF]
Giuntini E, Mengoni A, De Filippo C, et al. Large-scale genetic variation of the symbiosis-required megaplasmid pSymA revealed by comparative genomic analysis of Sinorhizobium meliloti natural strains. BMC Genomics.
Christian R Landry +23 more
core +1 more source
Imputation of genotypes from low- to high-density genotyping platforms and implications for genomic selection [PDF]
peer-reviewedThe objective of this study was to quantify the accuracy achievable from imputing genotypes from a commercially available low-density marker panel (2730 single nucleotide polymorphisms (SNPs) following edits) to a commercially available ...
J.F. Kearney +3 more
core +1 more source

