Results 31 to 40 of about 23,710,291 (301)

The molecular signaling of exercise and obesity in the microbiota-gut-brain axis

Frontiers in Endocrinology, 2022
Obesity is one of the major pandemics of the 21st century. Due to its multifactorial etiology, its treatment requires several actions, including dietary intervention and physical exercise.
Filipe M. Ribeiro, Filipe M. Ribeiro, Filipe M. Ribeiro, Maycon A. Silva, Victória Lyssa, Gabriel Marques, Henny K. Lima, Octavio L. Franco, Octavio L. Franco, Octavio L. Franco, Bernardo Petriz, Bernardo Petriz, Bernardo Petriz   +12 more
doaj   +1 more source

e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences [PDF]

, 2004
Krüger J, Sczyrba A, Kurtz S, Giegerich R. e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH.
Krüger, Jan, Sczyrba, Alexander ; https://orcid.org/, Giegerich, Robert, Kurtz, Stefan   +3 more
core   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

Genomic variations define divergence of water/wildlife-associated Campylobacter jejuni niche specialists from common clonal complexes [PDF]

, 2011
Although the major food-borne pathogen Campylobacter jejuni has been isolated from diverse animal, human and environmental sources, our knowledge of genomic diversity in C.
French, Nigel P., Hinds, Jason, Hall, N, Hepworth, Philip J., Gould, Katherine A., Gould, Katherine A, Adam A. Witney, Ashelford, Kevin E., Birtles, Richard J, Philip J. Hepworth, Kevin E. Ashelford, Nicola J. Williams, Winstanley, Craig, Howard Leatherbarrow, Wren, BW, Witney, AA, Birtles, Richard J., Neil Hall, French, Nigel P, Katherine A. Gould, Witney, Adam A., Hinds, J, Williams, Nicola J., Jason Hinds, Nigel P. French, Winstanley, C, Leatherbarrow, Howard, Paul Wigley, Williams, Nicola J, Birtles, RJ, Wren, Brendan W, Craig Winstanley, Mendonca, C, Mendonca, Chriselle, Hepworth, Philip J, Gould, KA, Wigley, Paul, Brendan W. Wren, Wren, Brendan W., Nick Dorrell, French, NP, Wigley, P, Hepworth, PJ, Leatherbarrow, H, Williams, NJ, Witney, Adam A, Dorrell, Nick, Chriselle Mendonca, Hall, Neil, Dorrell, N, Ashelford, KE, Ashelford, Kevin E, Richard J. Birtles   +52 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Comparison of analyses of the QTLMAS XIV common dataset. I: genomic selection [PDF]

, 2011
Background - For the XIV QTLMAS workshop, a dataset for traits with complex genetic architecture has been simulated and released for analyses by participants. One of the tasks was to estimate direct genomic values for individuals without phenotypes.
Tomasz Strabel, Pszczola, M.J., Sebastian Mucha, Mucha, S., Marcin Pszczola, Strabel, T., Wolc, A., Szydlowski, M., Anna Wolc, Maciej Szydlowski   +9 more
core   +1 more source

FOXO3a/PI3K/Akt pathway participates in the ROS- induced apoptosis triggered by α-ZEL and β-ZEL

Scientific Reports
Zearalenone (ZEN), an estrogenic mycotoxin, is one of the most common food and feed contaminants. Also, its metabolites α-zearalenol (α-ZEL) and β-zearalenol (β-ZEL) are considered to induce oxidative stress, however its effect in prostate cells is not ...
Dominika Ewa Habrowska-Górczyńska, Marta Justyna Kozieł, Kinga Anna Urbanek, Karolina Kowalska, Agnieszka Wanda Piastowska-Ciesielska   +4 more
doaj   +1 more source

Salmonella pathogenicity Island 1 undergoes decay in serovars adapted to swine and poultry

Microbiology Spectrum
Human salmonellosis is a high-priority foodborne disease worldwide. The main reservoir of Salmonella is livestock, mainly swine and poultry that are infected both by generalist serovars and serovars adapted to them.
Martina Tambassi, Melissa Berni, Chiara Bracchi, Ilaria Menozzi, Alessandra Dodi, Laura Mazzera, Marina Morganti, Erika Scaltriti, Stefano Pongolini   +8 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

AOH induces oxidative stress and DNA damage in ovarian cancer cells via modulation of GPER1 and HIF1α/PI3K/CLDNs signaling pathway

Scientific Reports
Claudins (CLDNs) are small proteins that form tight junctions (TJs) in cells and play a key role in various biological processes in cells. Previous results have shown that CLDNs expression can be regulated by hormones and, therefore, can also be ...
Marta Justyna Kozieł-Leszczyńska, Dominika Ewa Habrowska-Górczyńska, Kacper Piotr Leszczyński, Kinga Anna Urbanek, Agnieszka Wanda Piastowska-Ciesielska, Karolina Kowalska   +5 more
doaj   +1 more source