Results 51 to 60 of about 23,710,291 (301)

Deoxynivalenol Modulates the Viability, ROS Production and Apoptosis in Prostate Cancer Cells

Toxins, 2019
Deoxynivalenol (DON), known as vomitoxin, a type B trichothecene, is produced by Fusarium. DON frequently contaminates cereal grains such as wheat, maize, oats, barley, rye, and rice.
Dominika Ewa Habrowska-Górczyńska, Karolina Kowalska, Kinga Anna Urbanek, Kamila Domińska, Agata Sakowicz, Agnieszka Wanda Piastowska-Ciesielska   +5 more
doaj   +1 more source

Somatic alterations and mutational burden are potential predictive factors for metachronous development of early gastric cancer

Scientific Reports, 2020
The risk of developing metachronous gastric cancer (MGC) following curative endoscopic submucosal dissection (ESD) of early gastric cancer (EGC) remains even after eradicating Helicobacter pylori (HP) successfully.
Kazuhiro Sakuta, Yu Sasaki, Yasuhiko Abe, Hidenori Sato, Masakuni Shoji, Takao Yaoita, Makoto Yagi, Naoko Mizumoto, Yusuke Onozato, Takashi Kon, Ayumi Koseki, Sonoko Sato, Ryoko Murakami, Yuki Miyano, Yoshiyuki Ueno   +14 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genomic selection in dairy cattle [PDF]

, 2011
The objectives of this Ph.D. thesis were (1) to optimise genomic selection in dairy cattle with respect to the accuracy of predicting total genetic merit and (2) to optimise a dairy cattle breeding program using genomic selection. The study was performed
de Roos, A.P.W., Roos, A.P.W., de
core  

Author Correction: A B-ARR-mediated cytokinin transcriptional network directs hormone cross-regulation and shoot development

Nature Communications, 2018
The original version of this Article contained an error in Fig. 3. Panel b was inadvertently duplicated and the correct panel c was originally omitted. This error has been corrected in both the PDF and HTML versions of the Article.
Mingtang Xie, Hongyu Chen, Ling Huang, Ryan C. O’Neil, Maxim N. Shokhirev, Joseph R. Ecker   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A comon genomic framework for a diverse assembly of plasmids in the symbiotic nitrogen fixing bacteria [PDF]

, 2008
This work centres on the genomic comparisons of two closely-related nitrogen-fixing symbiotic bacteria, Rhizobium leguminosarum biovar viciae 3841 and Rhizobium etli CFN42.
Davila, Guillermo, Andrew W B Johnston, Lisa C Crossman, José L. Acosta, Luis Lozano, Castillo-Ramirez, Santiago, J Allan Downie, Meakin, Georgina, Andrew W. B. Johnston, McAnnula, Craig, Zara F Ghazoui, Georgios S. Vernikos, Hernandez-Gonzalez, Ismael, Johnston, Andrew W. B., Vernikos, Georgios S, Alan W. Walker, Young, J Peter W, Santiago Castillo-Ramírez, Crossman, Lisa C., Gonzalez, Victor, Hynes, Michael F., Downie, J. Allan, J. Peter W. Young, Hynes, Michael F, Víctor González, Johnston, Andrew W B, Lisa C. Crossman, J Peter W Young, Walker, Alan W, J. Allan Downie, David Romero, Craig McAnnula, Crossman, Lisa C, Downie, J Allan, Vernikos, Georgios S., Walker, Alan W., José L Acosta, Ismael Hernández-González, Julian Parkhill, Michael F. Hynes, Alan W Walker, Romero, David, Ghazoui, Zara F., Acosta, José L, Georgios S Vernikos, Michael F Hynes, Acosta, Jose L., Parkhill, Julian, Zara F. Ghazoui, Young, J. Peter W., Ghazoui, Zara F, Guillermo Dávila, Lozano, Luis, Georgina Meakin   +53 more
core   +2 more sources

Deep single-cell decoding of human pancreatic islets reveals T2D β-cell gene expression defects

The EMBO Journal
Pancreatic islets maintain glucose homeostasis through coordinated action of endocrine and affiliate cell types and are central to type 2 diabetes (T2D) genetics and pathophysiology.
Khushdeep Bandesh, Efthymios Motakis, Siddhi Nargund, Romy Kursawe, Vijay Selvam, Ansarullah, Redwan M Bhuiyan, Giray Naim Eryilmaz, Amelia M Willett, Jacqueline K White, Sai Nivedita Krishnan, Cassandra N Spracklen, Duygu Ucar, Michael L Stitzel   +13 more
doaj   +1 more source

Epigenetic silencing of a multifunctional plant stress regulator

eLife, 2019
The central regulator of the ethylene (ET) signaling pathway, which controls a plethora of developmental programs and responses to environmental cues in plants, is ETHYLENE-INSENSITIVE2 (EIN2).
Mark Zander, Björn C Willige, Yupeng He, Thu A Nguyen, Amber E Langford, Ramlah Nehring, Elizabeth Howell, Robert McGrath, Anna Bartlett, Rosa Castanon, Joseph R Nery, Huaming Chen, Zhuzhu Zhang, Florian Jupe, Anna Stepanova, Robert J Schmitz, Mathew G Lewsey, Joanne Chory, Joseph R Ecker   +18 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source