Results 101 to 110 of about 2,956,729 (308)

Exploratory Genomic Marker Analysis of Virulence Patterns in Listeria monocytogenes Human and Food Isolates

Foods
Listeria monocytogenes causes listeriosis, a severe foodborne disease with high mortality. Contamination with it poses significant risks to food safety and public health.
Valeria Russini, Maria Laura De Marchis, Cinzia Sampieri, Cinzia Onorati, Piero Zucchitta, Paola De Santis, Bianca Maria Varcasia, Laura De Santis, Alexandra Chiaverini, Antonietta Gattuso, Annarita Vestri, Laura Gasperetti, Roberto Condoleo, Luigi Palla, Teresa Bossù   +14 more
doaj   +1 more source

Genome-Wide Identification of Seven Polyamine Oxidase Genes in Camellia sinensis (L.) and Their Expression Patterns Under Various Abiotic Stresses

Frontiers in Plant Science, 2020
Polyamines (PAs) in plant play a critical role in growth and development and in response to environmental stress. Polyamine oxidase (PAO) is a flavin adenine dinucleotide dependent enzyme that plays a major role in PA catabolism.
Mengshuang Li, Jing Lu, Mingmin Tao, Mengru Li, Hua Yang, En-hua Xia, Qi Chen, Qi Chen, Xiaochun Wan   +8 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences [PDF]

, 2004
Krüger J, Sczyrba A, Kurtz S, Giegerich R. e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH.
Krüger, Jan, Sczyrba, Alexander ; https://orcid.org/, Giegerich, Robert, Kurtz, Stefan   +3 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Genomic Characterization of Campylobacter jejuni strain M1 [PDF]

, 2010
Campylobacter jejuni strain M1 (laboratory designation 99/308) is a rarely documented case of direct transmission of C. jejuni from chicken to a person, resulting in enteritis. We have sequenced the genome of C.
Toszeghy, Monique, Wassenaar, TM, Javed Muhammad A., Trudy M Wassenaar, Muhammad A. Javed, Ridley, A, Toszeghy Monique, Trudy M. Wassenaar, Wassenaar, Gertrude Maria, Manning, Georgia, Carsten Friis, Newell, Diane G., Ussery, David, Snipen, L, Hallin, PF, Javed, Muhammad A., Newell, DG, Monique Toszeghy, Peter F Hallin, Snipen Lars, Hallin Peter F., David W. Ussery, Manning, G, Toszeghy, M, Ussery, DW, Georgina Manning, Friis Carsten, Lagesen, K, Friis, C, Ussery David W., Muhammad A Javed, Javed, MA, Newell Diane G., Friis, Carsten, Lagesen Karin, Diane G Newell, Lars Snipen, Peter F. Hallin, Anne Ridley, Lagesen, Karin, Ridley, Anne, Manning Georgina, David W Ussery, Diane G. Newell, Hallin, Peter Fischer, Wassenaar Trudy M., Snipen, Lars, Karin Lagesen, Ridley Anne   +48 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Comparison of analyses of the QTLMAS XIV common dataset. I: genomic selection [PDF]

, 2011
Background - For the XIV QTLMAS workshop, a dataset for traits with complex genetic architecture has been simulated and released for analyses by participants. One of the tasks was to estimate direct genomic values for individuals without phenotypes.
Tomasz Strabel, Pszczola, M.J., Sebastian Mucha, Mucha, S., Marcin Pszczola, Strabel, T., Wolc, A., Szydlowski, M., Anna Wolc, Maciej Szydlowski   +9 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source