Results 121 to 130 of about 26,875,751 (309)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Bioinformatics Analysis of Whole Genome Sequencing Data to Estimation of Genomic Inbreeding Coefficient and Identification of Runs of Homozygosity Islands in Pekin Duck [PDF]

open access: yesپژوهشهای علوم دامی ایران
Introduction: Ducks are more resilient to unfavorable environmental conditions than other poultry, making them less susceptible to disease. They are easy to raise and exhibit rapid growth.
Hossein Mohammadi   +1 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Genomic data

open access: yes
Genomic data used for the study: Host-restrict Salmonella transition to endemicity is accompanied by localized resistome adaptationEnteritidis.zip: Genomic data from five strains of Salmonella Enteritidis (n=5).Gallinarum.zip: Genomic data from 535 strains of Salmonella Gallinarum.
openaire   +2 more sources

Genomic data

open access: yes, 2019
VCFfile containing information about common bottlenose dolphins and worksheets containing information on the biopsies collected and information abou stable isotopes of carbon and ...
openaire   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Genomic Bayesian prediction model for count data with Genotype × environment interaction

open access: yes, 2015
Genomic tools allow the study of the whole genome and are facilitating the study of genotype-environment combinations and their relationship with the phenotype.
He, Xinyao   +7 more
core   +1 more source

Data mining parasite genomes

open access: yesParasitology, 2004
The term ‘data mining’ can be used to describe any process where useful information is extracted from data with a large background of ‘noise’. In the context of a genome project, several stages involve data mining. Amongst the sequence data, ‘signals’ need to be detected that indicate the presence of interesting features.
openaire   +2 more sources

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

PLORC: A Pipelined Lossless Reference-Free Compression Architecture for FASTQ Files

open access: yesApplied Sciences
The rapid growth of genomic sequence datasets in a FASTQ format calls for efficient storage and transmission solutions. Compression–decompression algorithms for streaming applications offer a promising potential to address these challenges. In this paper,
Haori Zheng   +3 more
doaj   +1 more source

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