Results 91 to 100 of about 1,050,824 (300)

Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli

open access: yesAdvanced Science, EarlyView.
Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma   +18 more
wiley   +1 more source

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng   +14 more
wiley   +1 more source

Utilizing co-abundances of antimicrobial resistance genes to identify potential co-selection in the resistome

open access: yesMicrobiology Spectrum
The rapid spread of antimicrobial resistance (AMR) is a threat to global health, and the nature of co-occurring antimicrobial resistance genes (ARGs) may cause collateral AMR effects once antimicrobial agents are used.
Hannah-Marie Martiny   +5 more
doaj   +1 more source

Clustering of lymphoid neoplasms by cell of origin, somatic mutation and drug usage profiles: a multi-trait genome-wide association study

open access: yesBlood Cancer Journal
Lymphoid neoplasms (LNs) are heterogeneous malignancies arising from lymphoid cells, displaying diverse clinical and molecular features. Although LNs are collectively frequent, individual subtypes are rare, posing challenges for genetic association ...
Murat Güler, Federico Canzian
doaj   +1 more source

Whole genome sequencing to study SARS-CoV-2 transmission between university students and the surrounding community in Pittsburgh, Pennsylvania, 2020–2021

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
SARS-CoV-2 transmission was investigated between university students and the surrounding community using whole genome sequencing. Fourteen putative transmission clusters were identified. Proximity assessed using ZIP codes showed clustered cases were more
Vatsala Rangachar Srinivasa   +12 more
doaj   +1 more source

dBBQs: dataBase of Bacterial Quality scores

open access: yesBMC Bioinformatics, 2017
Background It is well-known that genome sequencing technologies are becoming significantly cheaper and faster. As a result of this, the exponential growth in sequencing data in public databases allows us to explore ever growing large collections of ...
Visanu Wanchai   +3 more
doaj   +1 more source

Public Health Applications of Genomic Epidemiology during the COVID-19 Pandemic [PDF]

open access: yes, 2022
The COVID-19 pandemic has brought the power of genomic epidemiology to the forefront. Harnessing the information stored in genomic sequences supplemented with traditional epidemiological data important questions about the drivers of transmission can be ...
Abdulnoor, Mariana
core  

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

open access: yesAdvanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu   +15 more
wiley   +1 more source

Tanzanian goat gut microbiomes adapt to roadside pollutants and environmental stressors

open access: yesMicrobiology Spectrum
The impact of environmental pollution reaching and affecting the gut microbiome is rising. Pollution from vehicle emissions can release compounds harmful to both animal and environmental health, and their effect on the host microbiome is yet to be ...
Emilie Egholm Bruun Jensen   +5 more
doaj   +1 more source

Canine Distemper Virus: Origins, Mutations, Diagnosis, and Epidemiology in Mexico

open access: yes
This review provides an overview of the canine distemper virus (CDV), a highly infectious pathogen causing severe disease in domestic dogs and wildlife. It shares genetic similarities with the human measles virus (HMV) in humans and the rinderpest virus (
Jaime R. Adame-Gallegos   +9 more
core   +1 more source

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