Results 51 to 60 of about 48,815 (295)

Estimating quantitative genetic parameters in wild populations:A comparison of pedigree and genomic approaches [PDF]

, 2014
The estimation of quantitative genetic parameters in wild populations is generally limited by the accuracy and completeness of the available pedigree information. Using relatedness at genome-wide markers can potentially remove this limitation and lead to
Pemberton, Josephine M, Ellis, Philip A., Pemberton, Josephine M., Bérénos, Camillo, Ellis, Philip A, Pilkington, Jill G., Pilkington, Jill G   +6 more
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Genomic prediction when some animals are not genotyped

Genetics Selection Evolution, 2010
Background The use of genomic selection in breeding programs may increase the rate of genetic improvement, reduce the generation time, and provide higher accuracy of estimated breeding values (EBVs).
Lund Mogens S, Christensen Ole F
doaj   +1 more source

Effects of the number of markers per haplotype and clustering of haplotypes on the accuracy of QTL mapping and prediction of genomic breeding values

, 2009
The aim of this paper was to compare the effect of haplotype definition on the precision of QTL-mapping and on the accuracy of predicted genomic breeding values.
Veerkamp Roel F, Theo HE Meuwissen, Egbert F Knol, Addie LJ Vereijken, Calus Mario PL, Vereijken Addie LJ, Knol, E.F., Schrooten, C., Windig, J.J., Meuwissen Theo HE, Knol Egbert F, Calus, M.P.L., Vereijken, A.L.J., Roel F Veerkamp, Jack J Windig, Windig Jack J, Veerkamp, R.F., Chris Schrooten, Schrooten Chris, Meuwissen, T.H.E., Mario PL Calus   +20 more
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The genome-wide analysis identified significant genomic loci explaining genetic variance for body conformation in Hanwoo (Korean cattle) cows

Journal of Applied Animal Research
Genomic data and objective traits (body conformation, growth and carcass features) could increase efficiency in cow selection. GWAS on carcass traits of Hanwoo cattle have been published; however, only a few studies are about body conformation traits ...
Heegun Lee, Dongjae Lee, Ji Min Kang, Seungwon Oh, Hyemi Do, Doo Ho Lee, Yeoungkuk Kim, Sung Jin Kim, Jihyun Son, Seung Hwan Lee, Duhak Yoon, Yangmo Koo   +11 more
doaj   +1 more source

Sensitivity of methods for estimating breeding values using genetic markers to the number of QTL and distribution of QTL variance

, 2010
The objective of this simulation study was to compare the effect of the number of QTL and distribution of QTL variance on the accuracy of breeding values estimated with genomewide markers (MEBV).
Bovenhuis, H., Bastiaansen John WM, Bovenhuis Henk, van Arendonk Johan AM, Calus Mario PL, John W. M. Bastiaansen, Mario P. L. Calus, Coster, A., Albart Coster, Henk Bovenhuis, Bastiaansen, J.W.M., Calus, M.P.L., Johan A. M. van Arendonk, Arendonk, J.A.M., van, van Arendonk, J.A.M., Coster Albart   +15 more
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Inclusion of genomic information in estimation of genetic parameters for body weights and visual scores in Nelore cattle

Revista Brasileira de Zootecnia, 2021
The aim of this study was to evaluate genomic information inclusion in genetic parameter estimation of standardized body weight at birth and at 240, 365, and 450 days of age, and visual scores for body structure, precocity, and body muscularity, measured
Rafael Nakamura Watanabe, Guilherme Batista do Nascimento, Priscila Arrigucci Bernardes, Rebeka Magalhães da Costa, Raysildo Barbosa Lôbo, Fernando Baldi, Danísio Prado Munari   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Identification of superior parental lines for biparental crossing via genomic prediction.

PLoS ONE, 2020
A parental selection approach based on genomic prediction has been developed to help plant breeders identify a set of superior parental lines from a candidate population before conducting field trials.
Ping-Yuan Chung, Chen-Tuo Liao
doaj   +1 more source

Breeding for sustainable milk production [PDF]

, 2013
The overall aim of the research reported in this thesis was to investigate ways to mitigate deterioration in functional traits and reduce the environmental impact of milk production.
Hansen Axelsson, Helen
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