Results 1 to 10 of about 2,587,498 (385)
SSW Library: An SIMD Smith-Waterman C/C++ Library for Use in Genomic Applications [PDF]
Summary: The Smith Waterman (SW) algorithm, which produces the optimal pairwise alignment between two sequences, is frequently used as a key component of fast heuristic read mapping and variation detection tools, but current implementations are either ...
Garrison, Erik+3 more
core +6 more sources
Libraries for genomic SELEX [PDF]
An increasing number of proteins are being identified that regulate gene expression by binding specific nucleic acidsin vivo. A method termed genomic SELEX facilitates the rapid identification of networks of protein-nucleic acid interactions by identifying within the genomic sequences of an organism the highest affinity sites for any protein of the ...
David Brown+3 more
openaire +4 more sources
Library on a slide for bacterial comparative genomics [PDF]
We describe a novel application of microarray technology for comparative genomics of bacteria in which libraries of entire genomes rather than the sequence of a single genome or sets of genes are arrayed on the slide and then probed for the presence or absence of specific genes and/or gene alleles.We first adopted a 96-well high throughput working ...
Zhang, Lixin+5 more
openaire +7 more sources
Preparation of Genomic Overexpression Library [PDF]
This protocol is used to identify/select for Escherichia coli genes that, when overexpressed in Vibrio cholerae Hsp33 (hslO gene) deletion mutant, protect against oxidative heat stress and, by extension, against HOCl-mediated protein damage. In the referenced publication, I found that V.
Wei-Yun Wholey
openaire +3 more sources
Wolbachia and DNA barcoding insects: patterns, potential and problems [PDF]
Wolbachia is a genus of bacterial endosymbionts that impacts the breeding systems of their hosts. Wolbachia can confuse the patterns of mitochondrial variation, including DNA barcodes, because it influences the pathways through which mitochondria are ...
BC Schmidt+75 more
core +15 more sources
The Enhanced Microbial Genomes Library [PDF]
Since the obtention of the complete sequence of Haemophilus influenzae Rd in 1995, the number of bacterial genomes entirely sequenced has regularly increased. A problem is that the quality of the annotations of these very large sequences is usually lower than those of the shorter entries encountered in the repository collections.
Perrière, G.+2 more
openaire +6 more sources
The Sleipnir library for computational functional genomics [PDF]
Abstract Motivation: Biological data generation has accelerated to the point where hundreds or thousands of whole-genome datasets of various types are available for many model organisms. This wealth of data can lead to valuable biological insights when analyzed in an integrated manner, but the computational challenge of managing such ...
Maria Chikina+3 more
openaire +3 more sources
Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II) [PDF]
A complete cDNA encoding the acrosin-trypsin inhibitor, HUSI-II, was used as a probe to isolate genomic clones from a human placenta library. Three clones which cover the entire HUSI-II gene were isolated and characterized.
Abelson+28 more
core +1 more source
Test: Construction of genomic libraries [PDF]
AbstractTerms to be familiar with before you start to solve the test: genomic library, gel filtration, restriction endonuclease, plasmid, sticky ends, blunt ends, ligation, recombinant DNA, bacterium transformation, denaturation and renaturation of DNA, satellite DNA, telomere, centromere, unique and repetitive sequences.
openaire +3 more sources
Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen [PDF]
Xenograft rejection of pigs organs with an engineered mutation in the GGTA-1 gene (GTKO) remains a predominantly antibody mediated process which is directed to a variety of non-Gal protein and carbohydrate antigens.
Byrne, GW+4 more
core +2 more sources