Results 11 to 20 of about 633,728 (345)
SSW library: an SIMD Smith-Waterman C/C++ library for use in genomic applications. [PDF]
PLoS ONE, 2013 The Smith-Waterman algorithm, which produces the optimal pairwise alignment between two sequences, is frequently used as a key component of fast heuristic read mapping and variation detection tools for next-generation sequencing data. Though various fast
Mengyao Zhao +3 more
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Wolbachia and DNA barcoding insects: patterns, potential and problems [PDF]
, 2012 Wolbachia is a genus of bacterial endosymbionts that impacts the breeding systems of their hosts. Wolbachia can confuse the patterns of mitochondrial variation, including DNA barcodes, because it influences the pathways through which mitochondria are ...
BC Schmidt +75 more
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Efficient Generation of Genome-wide Libraries for Protein–ligand Screens Using Gibson Assembly
Bio-Protocol, 2022 Genome-wide screens using yeast or phage displays are powerful tools for identifying protein–ligand interactions, including drug or vaccine targets, ligand receptors, or protein–protein interactions.
Tamara Sternlieb +3 more
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Implementation Science, 2021 Background Numerous implementation strategies to improve utilization of statins in patients with hypercholesterolemia have been utilized, with varying degrees of success.
Laney K. Jones +13 more
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The Enhanced Microbial Genomes Library [PDF]
Nucleic Acids Research, 1999 Since the obtention of the complete sequence of Haemophilus influenzae Rd in 1995, the number of bacterial genomes entirely sequenced has regularly increased. A problem is that the quality of the annotations of these very large sequences is usually lower than those of the shorter entries encountered in the repository collections.
Perrière, G. +2 more
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Large Insert Environmental Genomic Library Production [PDF]
Journal of Visualized Experiments, 2009 The vast majority of microbes in nature currently remain inaccessible to traditional cultivation methods. Over the past decade, culture-independent environmental genomic (i.e. metagenomic) approaches have emerged, enabling researchers to bridge this cultivation gap by capturing the genetic content of indigenous microbial communities directly from the ...
Marcus, Taupp +4 more
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Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II) [PDF]
, 1993 A complete cDNA encoding the acrosin-trypsin inhibitor, HUSI-II, was used as a probe to isolate genomic clones from a human placenta library. Three clones which cover the entire HUSI-II gene were isolated and characterized.
Abelson +28 more
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Molecular Plant-Microbe Interactions, 2000 A resistance (R) gene-rich 2S chromosomal segment from Triticum ventricosum contains a cereal cyst nematode (CCN; Heterodera avenae) R gene locus CreX and a closely linked group of genes (Sr38, Yr17, and Lr37) that confer resistance to stem rust ...
S. Seah +4 more
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Optimization of high molecular weight DNA extraction methods in shrimp for a long-read sequencing platform [PDF]
PeerJ, 2020 Marine organisms are important to global food security as they are the largest source of animal proteins feeding mankind. Genomics-assisted aquaculture can increase yield while preserving the environment to ensure sufficient and sustainable production ...
Pacharaporn Angthong +11 more
doaj +2 more sources
Whole-Genome Sequencing: Manual Library Preparation [PDF]
Cold Spring Harbor Protocols, 2016 This protocol describes a manual approach for the preparation of genomic DNA libraries suitable for Illumina sequencing. Genomic DNA fragments produced by shearing by sonication are ligated to adaptors and amplified by polymerase chain reaction (PCR). The amplified DNA, separated by size and gel-purified, is suitable for use as template in whole-genome
Elaine, Mardis, W Richard, McCombie
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