Results 41 to 50 of about 596,095 (346)
Mimotopes and Proteome Analyses Using Human Genomic and cDNA Epitope Phage Display [PDF]
, 2002 In the post-genomic era, validation of candidate gene targets frequently requires proteinbased strategies. Phage display is a powerful tool to define protein-protein interactions by generating peptide binders against target antigens.
Burge +29 more
core +3 more sources
Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries [PDF]
Scientific Reports, 2017 AbstractCRISPR-Cas9 technology has accelerated biological research becoming routine for many laboratories. It is rapidly replacing conventional gene editing techniques and has high utility for both genome-wide and gene-focussed applications. Here we present the first individually cloned CRISPR-Cas9 genome wide arrayed sgRNA libraries covering 17,166 ...
Metzakopian, Emmanouil +14 more
openaire +3 more sources
Fast genomic optical map assembly algorithm using binary representation [PDF]
arXiv, 2022 Reducing the cost of sequencing genomes provided by next-generation sequencing technologies has greatly increased the number of genomic projects. As a result, there is a growing need for better assembly and assembly validation methods. One promising idea is to use heterogeneous data in assembly projects. Optical Mapping (OM) is beneficial in validating
arxiv
The Parallelism Motifs of Genomic Data Analysis [PDF]
, 2020 Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these genomic data analysis problems require large scale computational platforms to meet both the memory and ...
arxiv +1 more source
10x Genomics Library Construction v1 [PDF]
, 2020 10x Genomics Library Construction
Graham J Etherington +9 more
openaire +1 more source
Construction and Characterization of Two Bacterial Artificial Chromosome Libraries of Grass Carp [PDF]
, 2010 Bacterial artificial chromosome (BAC) library is an important tool in genomic research. We constructed two libraries from the genomic DNA of grass carp (Ctenopharyngodon idellus) as a crucial part of the grass carp genome project.
Dong, Feng +8 more
core +1 more source
Preliminary Study of BAC Library Construction in Black Tiger Shrimp, Penaeus monodon
Walailak Journal of Science and Technology, 2011 Availability of shrimp genome information is necessary for shrimp genetic studies and large-insert DNA clones, bacterial artificial chromosome (BACs) serve as valuable tools for obtaining genomic sequences.
Suwit WUTHISUTHIMETHAVEE +3 more
doaj +1 more source
Collection of prokaryotic genome contents expectation rules from scientific literature [PDF]
arXiv, 2023 Shaped by natural selection and other evolutionary forces, an organism's evolutionary history is reflected through its genome sequence, content of functional elements and organization. Consequently, organisms connected through phylogeny, metabolic or morphological traits, geographical proximity, or habitat features are likely to exhibit similarities in
arxiv
Reducing assembly complexity of microbial genomes with single-molecule sequencing [PDF]
, 2013 Background: The short reads output by first- and second-generation DNA sequencing instruments cannot completely reconstruct microbial chromosomes. Therefore, most genomes have been left unfinished due to the significant resources required to manually close gaps in draft assemblies.
arxiv +1 more source
Genome Compression Against a Reference [PDF]
arXiv, 2020 Being able to store and transmit human genome sequences is an important part in genomic research and industrial applications. The complete human genome has 3.1 billion base pairs (haploid), and storing the entire genome naively takes about 3 GB, which is infeasible for large scale usage. However, human genomes are highly redundant.
arxiv