Results 41 to 50 of about 633,728 (345)

Epiviz Web Components: reusable and extensible component library to visualize functional genomic datasets [version 1; referees: 1 approved, 2 approved with reservations]

F1000Research, 2018
Interactive and integrative data visualization tools and libraries are integral to exploration and analysis of genomic data. Web based genome browsers allow integrative data exploration of a large number of data sets for a specific region in the genome ...
Jayaram Kancherla, Alexander Zhang, Brian Gottfried, Hector Corrada Bravo   +3 more
doaj   +1 more source

Genetic characterization of citrus rootstocks by using STMS markers : [P24] [PDF]

, 2008
STMS markers were used to characterize 41 Citrus rootstocks: A total of 10 Citrus-specific primers were tested, and 9 produced clear, reproducible and discrete bands.
Gonul, S., Incesu, M., Kacar, A.Yildiz, Kamiloglu, M.U., Ollitrault, Patrick, Tuzcu, O., Yesiloglu, Turgut, Yildirim, B.   +7 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Targeted sequencing library preparation by genomic DNA circularization

BMC Biotechnology, 2011
Background For next generation DNA sequencing, we have developed a rapid and simple approach for preparing DNA libraries of targeted DNA content. Current protocols for preparing DNA for next-generation targeted sequencing are labor-intensive, require ...
Myllykangas Samuel, Natsoulis Georges, Bell John M, Ji Hanlee P   +3 more
doaj   +1 more source

Cloning and characterisation of two subtilisin-like protease genes from Neotyphodium lolii : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Genetics at Massey University [PDF]

, 2000
PCR amplification of Neotyphodium lolii genomic DNA with degenerate primers detected two different sequences with homology to subtilisin-like proteases. These two PCR products were used to screen a N. lolii Lp19 genomic library.
McGill, Michelle Kay
core  

Joint assembly and genetic mapping of the Atlantic horseshoe crab genome reveals ancient whole genome duplication [PDF]

, 2013
Horseshoe crabs are marine arthropods with a fossil record extending back approximately 450 million years. They exhibit remarkable morphological stability over their long evolutionary history, retaining a number of ancestral arthropod traits, and are ...
Brockmann, H Jane, Havlak, Paul, Lv, Jie, Nossa, Carlos, Putnam, Nicholas H, Vincent, Kim, Yue, Jia-Xing   +6 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A highly redundant BAC library of Atlantic salmon (Salmo salar): an important tool for salmon projects

BMC Genomics, 2005
Background As farming of Atlantic salmon is growing as an aquaculture enterprise, the need to identify the genomic mechanisms for specific traits is becoming more important in breeding and management of the animal.
Koop Ben F, de Jong Pieter J, Osoegawa Kazutoyo, Frengen Eirik, Zhu Baoli, Thorsen Jim, Davidson William S, Høyheim Bjørn   +7 more
doaj   +1 more source

Phylogenetically diverse ureC genes and their expression suggest the urea utilization by bacterial symbionts in marine sponge Xestospongia testudinaria. [PDF]

PLoS ONE, 2013
Urea is one of the dominant organic nitrogenous compounds in the oligotrophic oceans. Compared to the knowledge of nitrogen transformation of nitrogen fixation, ammonia oxidization, nitrate and nitrite reduction mediated by sponge-associated microbes ...
Jing Su, Liling Jin, Qun Jiang, Wei Sun, Fengli Zhang, Zhiyong Li   +5 more
doaj   +1 more source

10x Genomics Library Construction v1 [PDF]

, 2020
10x Genomics Library Construction
Graham J Etherington, Darren Heavens, David Baker, Ashleigh Lister, Rose McNelly, Gonzalo Garcia, Bernardo Clavijo, Iain Macaulay, Wilfried Haerty, Federica Di Palma   +9 more
openaire   +1 more source