Results 91 to 100 of about 333,629 (311)
Signal Processing Methods for Genomic Sequence Analysis [PDF]
, 2007 Signal processing is the art of representing, transforming, analyzing, and manipulating signals. It deals with a wide range of signals, from speech and audio signals to images and video signals, and many others.
Yoon, Byung-Jun
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
ShinyGPAS: interactive genomic prediction accuracy simulator based on deterministic formulas
Genetics Selection Evolution, 2017 Background Deterministic formulas for the accuracy of genomic predictions highlight the relationships among prediction accuracy and potential factors influencing prediction accuracy prior to performing computationally intensive cross-validation ...
Gota Morota
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Global sequence features based translation initiation site prediction in human genomic sequences
Heliyon, 2020 Gene prediction has been increasingly important in genome annotation due to advancements in sequencing technology. Genome annotation further helps in determining the structure and function of these genes.
Neelam Goel +2 more
doaj +1 more source
Genomic selection in dairy cattle
, 2011 The objectives of this Ph.D. thesis were (1) to optimise genomic selection in dairy cattle with respect to the accuracy of predicting total genetic merit and (2) to optimise a dairy cattle breeding program using genomic selection. The study was performed
de Roos, A.P.W., Roos, A.P.W., de
core
Controlling population structure in the genomic prediction of tropical maize hybrids
, 2018 In tropical maize breeding programs where more than two heterotic groups are crossed, factors such as population structure (PS) can influence the achievement of reliable estimates of genomic breeding values (GEBVs) for complex traits.
Jianming Yu +26 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source