Results 151 to 160 of about 546,866 (293)

Integrating molecular markers into metabolicmodels improves genomic selection for Arabidopsis growth

, 2020
Hao Tong, Anika Küken, Zoran Nikoloski
openalex   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The role of selection in driving landscape genomic structure of the waterflea Daphnia magna

, 2012
Luisa Orsini, Joachim Mergeay, Joost Vanoverbeke, Luc De Meester   +3 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A low-coverage skim-sequencing and imputation pipeline for genomic selection. [PDF]

Plant Genome
Sthapit SR, Crain J, Larson S, Anderson JA, Bajgain P, DeHaan LR, Poland J.   +6 more
europepmc   +1 more source

Population structure correction for genomic selection through eigenvector covariates [PDF]

, 2017
Camila Ferreira Azevedo, Marcos Deon Vilela de Resende, Fabiano Ferreira da Silva, Moysés Nascimento, José Marcelo Soriano Viana, Mágno Sávio Ferreira Valente   +5 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Prediction of fruit texture with training population optimization for efficient genomic selection in apple [PDF]

, 2019
Morgane Roth, Mario Di Guardo, Walter Guerra, Hélène Muranty, Andrea Patocchi, Fabrizio Costa   +5 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The Establishment of a Sheep Embryo Genomic Selection System. [PDF]

Int J Mol Sci
Wang Y, Qin H, Li K, Hao J, Liu X, Chen D, Cheng L, He H, Wu R, Wu Y, Wang Y, Guo M, Li Q, An L, Tian J, Han H, Xi G.   +16 more
europepmc   +1 more source