Results 151 to 160 of about 3,983,457 (419)
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
Controlling the Overfitting of Heritability in Genomic Selection through Cross Validation. [PDF]
, 2017 In genomic selection (GS), all the markers across the entire genome are used to conduct marker-assisted selection such that each quantitative trait locus of complex trait is in linkage disequilibrium with at least one marker.
Jia, Zhenyu
core +2 more sources
Accuracy of genomic selection for grain yield and agronomic traits in soft red winter wheat
BMC Genetics, 2019 Genomic selection has the potential to increase genetic gains by using molecular markers as predictors of breeding values of individuals. This study evaluated the accuracy of predictions for grain yield, heading date, plant height, and yield components ...
Dennis N. Lozada +4 more
semanticscholar +1 more source
Ecological patterns of genome size variation and the origin of species in salamanders [PDF]
arXiv, 2015 Salamanders (urodela) have among the largest vertebrate genomes, ranging in size from 10 to over 80 pg. The urodela are divided into ten extant families each with a characteristic range in genome size. Although changes in genome size often occur randomly and in the absence of selection pressure, non-random patterns of genome size variation are evident ...
arxiv
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Reliability of genomic evaluation for egg quality traits in layers
BMC Genetics, 2020 Background Genomic evaluation, based on the use of thousands of genetic markers in addition to pedigree and phenotype information, has become the standard evaluation methodology in dairy cattle breeding programmes over the past several years. Despite the
David Picard Druet +6 more
doaj +1 more source
Accuracy of genomic selection in a rice synthetic population developed for recurrent selection. [PDF]
, 2013 Genomic selection is a promising breeding strategy for rapid improvement of complex traits. We investigated the accuracy of genomic estimate breeding values (GEBV) through cross validation in a synthetic population (SP) of broad genetic diversity ...
Ahmadi, Nourollah +5 more
core
MPAgenomics : An R package for multi-patients analysis of genomic markers [PDF]
, 2014 MPAgenomics, standing for multi-patients analysis (MPA) of genomic markers, is an R-package devoted to: (i) efficient segmentation, and (ii) genomic marker selection from multi-patient copy number and SNP data profiles. It provides wrappers from commonly
Blanck, Samuel +5 more
core +6 more sources
Early Selection Enabled by the Implementation of Genomic Selection in Coffea arabica Breeding
Frontiers in Plant Science, 2019 Genomic Selection (GS) has allowed the maximization of genetic gains per unit time in several annual and perennial plant species. However, no GS studies have addressed Coffea arabica, the most economically important species of the genus Coffea. Therefore,
Tiago Vieira Sousa +7 more
semanticscholar +1 more source
Genomic selection in livestock populations
Genetics Research, 2010 SummaryMost traits of economic importance in livestock are either quantitative or complex. Despite considerable efforts, there has been only limited success in identifying the polymorphisms that cause variation in these traits. Nevertheless, selection based on estimated breeding values (BVs), calculated from data on phenotypic performance and pedigree ...
Goddard, Michael E. +2 more
openaire +3 more sources