Results 161 to 170 of about 546,866 (293)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

GS4PB: An R Shiny application to facilitate a genomic selection pipeline for plant breeding. [PDF]

Plant Genome
Ramasubramanian V, Wartha CA, Singh L, Vitale P, Ru S, Bhusal SJ, Lorenz AJ.   +6 more
europepmc   +1 more source

Genomic optimum contribution selection and mate allocation using JuMP [PDF]

Patrik Waldmann
openalex   +1 more source

Statistical considerations for genomic selection [PDF]

, 2017
Huimin Kang, Lei Zhou, Jianfeng Liu
openalex   +1 more source

HaploBlocks: Efficient Detection of Positive Selection in Large Population Genomic Datasets

, 2023
Benedikt Kirsch-Gerweck, Leonard Bohnenkämper, Michel T Henrichs, Jarno Alanko, Hideo Bannai, Bastien Cazaux, Pierre Peterlongo, Joachim Bürger, Jens Stoye, Yoan Diekmann   +9 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Normalized cumulative gain as an alternative evaluation measure for genomic selection models. [PDF]

Genet Sel Evol
Heinrich F, Lange TM, Ramzan F, Gültas M, Schmitt AO.   +4 more
europepmc   +1 more source

Comparative population genomics reveals genetic divergence and selection in lotus, Nelumbo nucifera [PDF]

, 2020
Ye Li, Fenglin Zhu, Xingwen Zheng, Manli Hu, Chen Dong, Ying Diao, Youwei Wang, Keqiang Xie, Zhongli Hu   +8 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Genomic prediction for Nordic Red Cattle using one-step and selection index blending [PDF]

, 2012
Gloria H. Su, Per Madsen, U. Nielsen, Esa Mäntysaari, Gert Pedersen Aamand, Ole Fredslund Christensen, Mogens Sandø Lund   +6 more
openalex   +1 more source