Results 171 to 180 of about 3,983,457 (419)

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Genomic Selection with Allele Dosage in Panicum maximum Jacq.

G3: Genes, Genomes, Genetics, 2019
Genomic selection is an efficient approach to get shorter breeding cycles in recurrent selection programs and greater genetic gains with selection of superior individuals.
Letícia A. de C. Lara, Mateus F. Santos, L. Jank, L. Chiari, M. D. M. Vilela, R. Amadeu, J. P. D. dos Santos, G. S. Pereira, Z. Zeng, A. Garcia   +9 more
semanticscholar   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Genomic selection needs to be carefully assessed to meet specific requirements in livestock breeding programs

Frontiers in Genetics, 2015
Genomic selection is a promising development in agriculture, aiming improved production by exploiting molecular genetic markers to design novel breeding programs and to develop new markers-based models for genetic evaluation.
Elisabeth eJonas, Dirk-Jan ede Koning
doaj   +1 more source

Genomic Selection—Considerations for Successful Implementation in Wheat Breeding Programs

Agronomy, 2019
In order to meet the goal of doubling wheat yield by 2050, breeders must work to improve breeding program efficiency while also implementing new and improved technologies in order to increase genetic gain. Genomic selection (GS) is an expansion of marker
D. Larkin, Dennis N. Lozada, R. E. Mason
semanticscholar   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

Pea genomic selection for Italian environments

BMC Genomics, 2019
A thorough verification of the ability of genomic selection (GS) to predict estimated breeding values for pea (Pisum sativum L.) grain yield is pending. Prediction for different environments (inter-environment prediction) has key importance when breeding
P. Annicchiarico, N. Nazzicari, L. Pecetti, M. Romani, L. Russi   +4 more
semanticscholar   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Genomic Selection in Animal Breeding [PDF]

BIO Web of Conferences
Genomic selection endeavors to determine the reproductive values and characteristics of offspring in a given population through the utilization of high-density genetic markers. In contemporary breeding methods, classical approaches involve extended labor-
Demircioglu Hasan Batuhan
doaj   +1 more source

Cassava yield traits predicted by genomic selection methods

PLoS ONE, 2019
Genomic selection (GS) has been used to optimize genetic gains when phenotypic selection is considered costly and difficult to measure. The objective of this work was to evaluate the efficiency and consistency of GS prediction for cassava yield traits ...
L. R. B. D. Andrade, M. B. Sousa, E. J. Oliveira, M. Resende, C. F. Azevedo   +4 more
semanticscholar   +1 more source