Results 171 to 180 of about 4,045,535 (372)
Genomic selection in oil palm (Elaeis guineensis Jacq.) [PDF]
, 2014 Genomic selection (GS) can increase the genetic gain in plants. In perennial crops, this can be achieved via shortened breeding cycles and increased selection intensity. Our objective was to obtain the first empirical estimate of GS accuracy in oil palm (
Bouvet, Jean-Marc +11 more
core
Accuracy of genomic selection for grain yield and agronomic traits in soft red winter wheat
BMC Genetics, 2019 Genomic selection has the potential to increase genetic gains by using molecular markers as predictors of breeding values of individuals. This study evaluated the accuracy of predictions for grain yield, heading date, plant height, and yield components ...
Dennis N. Lozada +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Genomic Selection with Allele Dosage in Panicum maximum Jacq.
G3: Genes, Genomes, Genetics, 2019 Genomic selection is an efficient approach to get shorter breeding cycles in recurrent selection programs and greater genetic gains with selection of superior individuals.
Letícia A. de C. Lara +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Controlling the Overfitting of Heritability in Genomic Selection through Cross Validation [PDF]
, 2017 Zhenyu Jia
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Prediction of fruit texture with training population optimization for efficient genomic selection in apple [PDF]
, 2019 Morgane Roth +5 more
openalex +1 more source