Results 191 to 200 of about 3,983,457 (419)

Turning science on robust cattle into improved genetic selection decisions

open access: yesAnimal, 2012
More robust cattle have the potential to increase farm profitability, improve animal welfare, reduce the contribution of ruminant livestock to greenhouse gas emissions and decrease the risk of food shortages in the face of increased variability in the ...
P.R. Amer
doaj  

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

How to infer relative fitness from a sample of genomic sequences

open access: yes, 2013
Mounting evidence suggests that natural populations can harbor extensive fitness diversity with numerous genomic loci under selection. It is also known that genealogical trees for populations under selection are quantifiably different from those expected
Dayarian, Adel, Shraiman, Boris I
core   +1 more source

Genomic selection: A breakthrough technology in rice breeding

open access: yesCrop Journal, 2021
Yang Xu   +10 more
semanticscholar   +1 more source

Prospects and Challenges of Applied Genomic Selection—A New Paradigm in Breeding for Grain Yield in Bread Wheat

open access: yesThe Plant Genome, 2018
Genomic prediction of grain yield across nurseries or years is challenging, because of genotype × environment interactions. Prediction accuracies can be improved by having at least one full‐sib in the training population.
Philomin Juliana   +10 more
semanticscholar   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

Genomic prediction of traits related to canine hip dysplasia

open access: yesFrontiers in Genetics, 2015
Increased concern for the welfare of pedigree dogs has led to development of selection programs against inherited diseases. An example is canine hip dysplasia (CHD), which has a moderate heritability and a high prevalence in some large-sized breeds.
Enrique eSanchez-Molano   +5 more
doaj   +1 more source

Genome-wide profiling of human cap-independent translation-enhancing elements. [PDF]

open access: yes, 2013
We report an in vitro selection strategy to identify RNA sequences that mediate cap-independent initiation of translation. This method entails mRNA display of trillions of genomic fragments, selection for initiation of translation and high-throughput ...
Briones, Natalia   +10 more
core  

SWEEPFINDER2: Increased sensitivity, robustness, and flexibility

open access: yes, 2015
SweepFinder is a popular program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the ...
DeGiorgio, Michael   +4 more
core   +1 more source

Genomic selection on breeding time in a wild bird population

open access: yesEvolution Letters, 2019
Artificial selection experiments are a powerful tool in evolutionary biology. Selecting individuals based on multimarker genotypes (genomic selection) has several advantages over phenotype‐based selection but has, so far, seen very limited use outside ...
P. Gienapp   +3 more
semanticscholar   +1 more source

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