Results 191 to 200 of about 546,866 (293)

Signatures of selection analyses reveal genomic differences among three heavy pig breeds that constitute the genetic backbone of a dry-cured ham production system

Francesca Bertolini, G. Schiavo, Samuele Bovo, Anisa Ribani, Stefania Dall’Olio, Paolo Zambonelli, M. Gallo, L. Fontanesi   +7 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Genomic selection and reproducibility: are complex models distracting us from true scientific validity in the presence of genotype-by-environment interaction? [PDF]

G3 (Bethesda)
Howard R, Lipka AE.
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Assessment of the potential for genomic selection to improve resistance to fusarium stalk rot in maize. [PDF]

Front Plant Sci
Lohithaswa HC, Showkath Babu BM, Sowmya MS, Banakar SK, Mallikarjuna N, Jadesha G, Mallikarjuna MG, Balasundara DC, Anand P.   +8 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Genomic selection of maize test-cross hybrids leveraged by marker sampling. [PDF]

Plant Genome
Bernardeli A, Guilhen JHS, Oliveira ICM, Guimarães LJM, Borém A, Jarquin D, Pastina MM.   +6 more
europepmc   +1 more source

Comparison of selection methods of regression variables applied to genomic data and NIR spectroscopy

, 2018
Roberta de Amorim Ferreira
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Genomic Selection for Economic Traits in Inner Mongolia Cashmere Goats by Integrating GWAS Prior Information. [PDF]

Vet Sci
Xi H, Xu Q, Yao H, Shen Z, Zhou B, Lv Q, Li J, Wang R, Zhang Y, Su R, Wang Z.   +10 more
europepmc   +1 more source