Results 221 to 230 of about 3,983,457 (419)

Estimation of DNA Sequence Context-dependent Mutation Rates Using Primate Genomic Sequences: Application to Estimation of Selection Bias in Protein (Human TP53) Evolution [PDF]

, 2007
Wei Zhang
openalex   +2 more sources

Genomic breeding value prediction: methods and procedures*

Animal, 2010
Animal breeding faces one of the most significant changes of the past decades – the implementation of genomic selection. Genomic selection uses dense marker maps to predict the breeding value of animals with reported accuracies that are up to 0.31 higher
M.P.L. Calus
doaj  

SK18 diphasmid for constructing genomic libraries with blue/white selection, multiple cloning sites, and with the M13 and λ ori

, 1989
Eugene R. Zabarovsky, O. V. Turina, М. К. Нурбеков, Lev L. Kisselev   +3 more
openalex   +2 more sources

Using genomic DNA-based probe-selection to improve the sensitivity of high-density oligonucleotide arrays when applied to heterologous species [PDF]

, 2005
John P. Hammond, Martin R. Broadley, David J Craigon, Janet Higgins, Zoe F Emmerson, Henrik J Townsend, Philip J. White, Sean May   +7 more
openalex   +1 more source

Bias due to genomic selection [PDF]

, 2009
absent
Patry, Clotilde, Ducrocq, Vincent
openaire   +3 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Direct selection: a method for the isolation of cDNAs encoded by large genomic regions.

, 1991
Michael Lovett, Juha Kere, L.M. Hinton
openalex   +1 more source

Differential selection and mutation between dsDNA and ssDNA phages shape the evolution of their genomic AT percentage. [PDF]

, 2005
Xuhua Xia, Kwok‐Yung Yuen
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

A role for genomic instability in the development of, and selection for, radioresistant cell variants

, 2000
W.F. Morgan, James Corcoran, Charles L. Limoli, R. Jordan, Joseph Schwartz   +4 more
openalex   +1 more source