Results 231 to 240 of about 546,866 (293)

Evidence of early genomic selection in Holstein Friesian across African and European ecosystems. [PDF]

BMC Genomics
Gao J, Gonzalez-Prendes R, Liu Y, Kantanen J, Ginja C, Ghanem N, Kugonza DR, Makgahlela M, Bovenhuis H, Groenen MAM, Crooijmans RPMA.   +10 more
europepmc   +1 more source

Use of simulation to optimize a sweet corn breeding program: implementing genomic selection and doubled haploid technology [PDF]

Marco Antônio Peixoto, Igor Ferreira Coelho, Kristen A. Leach, Thomas Lübberstedt, Leonardo Lopes Bhering, Márcio F. R. Resende   +5 more
openalex   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Deep learning empowers genomic selection of pest-resistant grapevine. [PDF]

Hortic Res
Gan Y, Liu Z, Zhang F, Xu Q, Wang X, Xue H, Su X, Ma W, Long Q, Ma A, Huang G, Liu W, Xu X, Sun L, Zhang Y, Liu Y, Fang X, Li C, Yang X, Wei P, Fan X, Zhang C, Zhang P, Liu C, Zhou L, Zhang Z, Wang Y, Liu Z, Zhou Y.   +28 more
europepmc   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Leveraging GWAS-Identified Markers in Combination with Bayesian and Machine Learning Models to Improve Genomic Selection in Soybean. [PDF]

Int J Mol Sci
Xue Y, Tang X, Zhu X, Zhang R, Yao Y, Cao D, He W, Liu Q, Luan X, Shu Y, Liu X.   +10 more
europepmc   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

A Framework Integrating GWAS and Genomic Selection to Enhance Prediction Accuracy of Economical Traits in Common Carp. [PDF]

Int J Mol Sci
Sun Z, Fu Y, Zhu X, Zhang R, Shu Y, Zheng X, Hu G.   +6 more
europepmc   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source